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Loryna for Premenstrual Dysphoric Disorder User Reviews

Rating: 4.7

Loryna has an average rating of 4.7 out of 10 from a total of 17 reviews for the treatment of premenstrual dysphoric disorder. 41% of reviewers reported a positive experience, while 53% reported a negative experience.

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Reviews for Loryna

Commonly mentioned side effects
  • adh...
  • Taken for 1 to 6 months
  • March 19, 2023

"Okay, so I’m here for all the people who are terrified and see all these bad reviews. Keep in mind, people are more likely to share bad experiences, so just remember there are good ones too! I used to take Gianvi, and then it sadly was discontinued. CVS started giving me Nikki. It was awful. So the pharmacist looked up other generics of Yaz, and he ordered me Loryna. I figured I’d give it a go. It helps me a lot, I used to have awful cramps, nausea, and migraines before my period. I also would have awful mood swings and would lash out at my husband. I haven’t had that at all with Loryna! I also skip the placebos because my periods are so rough, and that makes my life so much easier. If you’re scared and see all these reviews, just remember, everyone’s different! Give it a try, and if it doesn’t work, it’ll be okay! Just let your ob-gyn or pharmacist know."

10 / 10
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13 Report
  • Mat...
  • Taken for less than 1 month
  • March 19, 2022

"I'm on day 5 of Loryna, and I am so suicidal I considered going to the hospital. I was trying it for PMDD, I did have success before on Lo Loestrin FE, but I was having side effects of melasma and low libido, so I wanted to try something else. This is awful. I've also had nightmares and nausea since starting it."

1 / 10
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7 Report
  • Loz...
  • January 27, 2020

"Loryna has helped my PMDD somewhat. I also have cut meat mostly and am very active and limit drinking. My issues with this are breast pain, constant bloat. I thought I had a sensitive gut before, but have issues where my pants sometimes don’t fit by the evening. I drink tons of water and limit inflammatory foods, but it still doesn’t help. I bleed randomly. Right now, I have 5 pills left before the white pills and am bleeding. I spotted for a week before that. This happens without rhyme or reason. My skin looks good, but to be honest, I take good care of it. I am sure it’s contributing, but habits are too. The headaches I get on this medication are terrifying and sometimes last three days. I felt so validated finding this forum because I thought something was really wrong. My libido is significantly lower, and it’s difficult to achieve arousal. I never had an issue with that before. The worst: my blood pressure is now elevated. I just asked my doctor about an alternate treatment."

2 / 10
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10 Report
  • lif...
  • Taken for less than 1 month
  • July 16, 2017

"I tried to take Beyaz again, which was the only birth control I liked ever. My insurance refuses to cover it, so I figured a Yaz generic would be similar enough. I firmly believe what's in this generic is not at all the same as the original. How could the same exact medicine affect me so negatively? I took this for two weeks and felt like I was physically having a panic attack all the time. I got this to help me during my hardest time of the period (right before I get it) and spent these past two weeks losing my mind. I do not even believe the positive reviews on this site are legitimate. I was tired, hungry, nauseous, and unable to do my daily tasks. No sex drive. I tried taking it at night to combat these negative things. No escape. Don't take it."

1 / 10
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14 Report
  • Irr...
  • Taken for less than 1 month
  • September 13, 2017

"I recently started taking birth control for my PMDD, and this is my second pack (Gianvi with my 1st, Loryna for the 2nd). I'm also diagnosed with GAD (Generalized Anxiety Disorder) with panic disorder and depressive symptoms. When I was taking Gianvi, I had no anxiety or mood swings, a short period that lasted 4 days (it used to be 7-9), and my relationship with people, especially my boyfriend, was stable. It's only been my third week of using Loryna, and my anxiety and depression are back. I break out easily, I've been feeling this terrible ache in my lower abdomen, and I've been constantly arguing with my boyfriend. I'm definitely calling my doctor to change prescriptions!!!"

1 / 10
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11 Report

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  • Cor...
  • Taken for 1 to 6 months
  • August 4, 2024

"I was prescribed this for my severe premenstrual dysphoric disorder. I would feel unlike myself for a majority of the month, feeling normal only after I finished my period. Severe depression, mood swings, painful periods, if you know, you know. The first week on Loryna was tough. Stomach aches, nausea, weakness. Switched to taking it at 7 PM instead of 10 AM, made a HUGE difference. After about a month, side effects as a whole subsided. I no longer felt my terrible mood swings, no more tender and painful breasts and periods, no more awful body aches, no more irritation and frustration, depression, anxiety! Life changer! I hit my highest in weight at 240 lb. On the pill, since I wasn't stressing anymore and depressed, I made great progress on my weight loss! Lost 20 lbs in 3 months and still counting! I no longer have my awful bouts of sadness, I get a little moody before my period, but it's only a couple of days and it's not severe! So happy with this!"

10 / 10
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  • BWa...
  • September 5, 2016

"I started Loryna for PMDD. Started on a Sunday. By Tuesday, I had 3 enormous, painful zits. By Thursday, I was in severe abdominal cramping pain. Similar to period/early labor pains. By Saturday, they landed me in the ER. Every lab test and ultrasound/X-ray was normal, so the only diagnosis that made sense was the pill. I'm currently on day 9 of my period, which would normally only last 5-6 days. Needless to say, it's in the trash now."

1 / 10
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  • Bri...
  • Taken for 1 to 6 months
  • July 1, 2023

"I took the Loryna birth control for approximately 3 months. I stopped taking it because of my insurance being terminated due to job loss. Here's my 3-month journey with Loryna birth control pill: On the first month taking this medication, I experienced a very, very painful, clotty, and heavy, long-lasting period. It lasted 2 days longer than my usual flow, totally 7 days (I normally bled for 5). During this time frame, I experienced severe PMDD symptoms. Despite that, I still continue to keep taking it. On my second month experience, it was a whole lot simpler and my period was regular again. Also, my PMDD symptoms were not as severe. I still had some sorrow and weeping, but no anger or fear. By the third month, I realized I wasn't suffering from proctalgia fugax symptoms at all (most likely due to the birth control preventing ovulation). It's been almost a month now of being birth control-free and I really don't miss ovulating. I never experience any prolonged bleeding. I rate this as 8."

8 / 10
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  • Zan...
  • Taken for less than 1 month
  • July 23, 2018

"Just got on this pill, most people said they felt super sick almost immediately (I’ve felt sick right away on other BCs) and I’m fine. Appetite is the same, slight headache the first night but nothing I couldn’t deal with. I’m hoping this pill works for me, but I have good feelings about it. Will update later."

8 / 10
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  • Mel...
  • August 12, 2021

"I was prescribed this medication for severe PMDD and severe dysmenorrhea. I have only been on this medication for 2 weeks so far, and I have not had any noticeable (I also take citalopram 10-20 mg QD) side effects either other than a bit more frequent urination. I have naturally clear skin, but it seems to almost have a glow to it now, though honestly. I did have about 4 days of mild spotting/bleeding initially, but no cramping really, and that has stopped. I have mood swings, but I have those off of the birth control, so they haven't gotten any worse or better. I tried to stop the citalopram to see what Loryna would do on its own, and I had HORRIBLE withdrawal side effects. I don't advise anybody to cold turkey stop that medication while also on a hormonal birth control or period. I rated Loryna an 8 because I don't know how I will feel 2 more months down the road. I have a history of truly bad mental health side effects from hormonal birth control. Will update then."

8 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • December 9, 2021

"Was given this in addition to Celexa to help with PMDD and general anxiety disorder. Was taking Jolessa for the past year, and it made my anxiety/PMDD extremely worse. On the second month of Loryna, and I am absolutely in love with this pill. In combo with my anxiety meds, it has taken away all bloat, my weight has started to decrease (gained 20 pounds on Jolessa), and my energy has returned. First period on Loryna was only 2 1/2 days with zero cramping. No acne. My anxiety and PMDD are still there, but instead of 2 weeks of nightmare, I had maybe 2 really bad days."

10 / 10
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  • cic...
  • Taken for 1 to 6 months
  • April 21, 2021

"I started Loryna when I was bleeding extremely heavily for about 4 months. The minute I started it, the bleeding stopped, and I was happy, of course, but a couple of days in, I was feeling depressed and easily agitated off and on. I stopped taking it after 3 months and felt back to my normal self again. Now I started taking it again because I still had refills, and the bleeding started up again. This time, I feel much worse than I did before. Depressed and agitated ALL THE TIME! I also cry for nothing! This has been a really horrible experience."

4 / 10
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  • Mom...
  • Taken for 1 to 6 months
  • February 22, 2018

"After two months, my daughter is having a severe adverse reaction. She has had a CT, MRI, and is now being treated by a cardiologist for long-term monitoring due to her risk of blood clotting and heart/stroke-related symptoms. This is a very dangerous drug - and for what? Acne and PMDD? Please research before taking. Stop immediately with ANY adverse side effects."

1 / 10
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  • meo...
  • Taken for 1 to 6 months
  • January 20, 2025

"My PMDD was so severe I had to make a 'rule' that I couldn't end my life during PMS. This genuinely saved my life. My biggest regret in life was being too ashamed to ask for birth control because I was 13. I was on Seasonale, and taking it every day ended up with me bleeding for weeks. I didn't know what to do about it, so I just switched to the Depo shot. This made my appetite uncontrollable, and I developed binge eating disorder or bulimia. But since switching to Yaz/Loryna, I am able to be off my ADHD medication and not binge eat. I am so glad to be off Depo Provera, and aside from having horrible cramping when I attempted to do the placebo days or forgot a pill (these happened 2 days in a row, so it could've been a bowel problem), I have had no issues."

10 / 10
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  • Dev...
  • Taken for 1 to 6 months
  • August 16, 2021

"I've been taking this for over a month, and I feel miserable. I will say it has helped with my acne, and it helped during that two-week period before my cycle where my PMDD really kicked in, but now starting this second pack of pills, I feel like a worthless monster. All I want to do is lay around, my house is a disaster. I don’t want to spend time with my family, and my sex drive is a -10. I have generalized anxiety and depression, which I take medication for, and I’ve never felt lower in my life than when I started taking this. It helps the PMDD and acne, but it is not worth losing all my joy."

3 / 10
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  • Mel...
  • Taken for 1 to 6 months
  • August 26, 2021

"I was prescribed this for my severe PMDD. Initially, I had several days of breakthrough bleeding, once that stopped, my skin slowly started becoming terrible. My once perfectly clear skin now has blackheads all over my chin, my pores were starting to look bigger and just greasy, and now my chin has zits all over it, some under the skin. My forehead started breaking out too. I also developed restless leg syndrome, my stomach bloat is insane, and the closer I got to the placebo pills, I felt constantly angry and ready to snap on everybody. It was starting to severely affect my moods and relationship. I also would feel very nauseated and just ill if I waited too long between meals, almost like when I was pregnant. I stopped after the first pack, and it's now in the garbage. Would not recommend to anybody. It was free under my insurance, literally the only positive."

1 / 10
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  • Lor...
  • Taken for 1 to 6 months
  • May 15, 2023

"My daughter has been on this for almost three months. Her mood swings are so out of control. Her period is out of sync. She has migraines and stomach issues constantly. Overall, she is miserable. Definitely getting off of this for sure. Going to see the OBGYN soon."

1 / 10
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Learn more about Premenstrual Dysphoric Disorder