Doxepin for Anxiety User Reviews

• Nev...
• June 13, 2021

"I have suffered from anxiety, depression, eating disorders, sleep issues since my teens. I began doxepin in combination with hydroxyzine, and I have experienced life-changing results. I used to sleep 12 hours and would still be exhausted. My cognitive function is amazing. I no longer feel sick all the time, I wake up completely alert instead of groggy and in physical pain. The hydroxyzine has been very effective when I begin to notice myself getting overstimulated during the day. My anxiety essentially turns down to normal, which has been a game-changer for me. Fears that had been extremely taxing on me mentally and physically due to excessive anxiety and irregular sleep and eating are easy now. I used to crumble under pressure, procrastinate everything rather than just doing it... I am frankly blown away by the results. I feel normal for the first time in my life."

• Pmi...
• April 23, 2021

"I’m taking 10mg doxepin in the evening. This is an older medicine that came out in 1969. This means that it has been around a long time and so what side effects there are are largely known by now. I opted for the 10mg since 3mg & 6mg (for insomnia) are expensive. I have suffered with anxiety & insomnia for a few years now. The higher mg’s (150mg-300mg) target areas of the brain affected by depression and anxiety (per MD). The 10mg has helped both with my insomnia & anxiety. I have taken many different medicines to deal with my anxiety. I was having insomnia with Celexa & had to take Xanax to deal with it, it worked aside from insomnia. I have struggled for a long time to find something that actually works & I am grateful that I am able to sleep & be free of anxiety! I read the reviews on doxepin prior to taking it & saw several that said it caused them to gain weight. This has not been my experience. I’ve had no side effects &, best of all, I’ve gotten my life back."

• Mar...
• Taken for 1 to 6 months
• April 27, 2018

"I’ve been struggling with PTSD for well over 10 years. Incapacitating anxiety, insomnia, depression. I could no longer function at all. I’ve tried everything! Nothing worked unless it made it worse and gave me extremely bad side effects. It was so excruciating that I really wanted to throw in the towel. I started Doxepin about 6 or weeks ago. Then suddenly the intensity of my disorder severely decreased. Almost overnight and has continued to without any dips in its time. I’m absolutely stunned! I’m still on the low starting dose too. I’m overjoyed by relief. I’ve become myself again. I can actively participate in daily activities like showering, leaving my house, answering the phone, basic things that people take for granted. Before, I was totally immobilized. I hope this continues"

• Ang...
• January 8, 2021

"I was on doxepin a while ago but weaned myself off it, thinking my anxiety wasn't that bad and I could try mindfulness/natural herbs. Well, that wasn't a good idea. Ended up in the hospital with heat arrhythmia and terrible anxiety/no sleep. I didn't realize how well this medication works while on it. After 2 days back on it, I'm sleeping and my heart has gone back to normal. I'm on 75mg and will be for life. I have had no unpleasant side effects apart from going off it. Saved my life really. 10/10"

• Mar...
• Taken for 10 years or more
• October 16, 2020

"After most of my life, at least 40 years. I have been on tricyclic antidepressants. It took a long time to get diagnosed. I see my condition as generalized anxiety, as I had no real classic signs of depression. Ten years ago, I ended up in the hospital, and they gave me antipsychotic medications, Seroquel, nothing worked. After giving me Xanax, which, within an hour, I was back to myself, they discharged me on Xanax. I saw my psychiatrist of 20 years, and he prescribed Doxepin, and within 4 weeks, I came literally out of a nightmare. I still have 2 hours to come around in the morning, but it sure is better than the extreme anxiety and worry I was experiencing. So I don't want to upset the apple cart, as I have, so I continue to keep up my regime, and I'm quite pleased with having a life without extreme anxiety, panic disorder, which is my exact diagnosis."

• Got...
• Taken for 6 months to 1 year
• March 20, 2016

"I was experiencing very bad anxiety and was having panic attacks nearly every day. I also had issues sleeping, I couldn't sleep more than 2 hours at a time. My doctor put me on 75mg once daily at bedtime. I feel like my old self. I am sleeping very well at night, and I haven't had a panic attack in 8 months. Doxepin gave me my life back."

• DKT...
• May 17, 2015

"Been on many SSRIs, a few SNRIs, and some of the TCAs. I took Tofranil (imipramine) for about 6 months on a starting dose of 25 mg and eventually increased slowly to 125 mg. Over the course of those 6 months, my anxiety was under control for the most part, but I developed myoclonus and had to stop taking the drug. I switched to Sinequan (doxepin) 25 mg, increased to 75 mg, divided into 25 mg three times a day and have done well, without any side effects besides mild fatigue. No bad thoughts, lingering anxiety or panic attacks. Very successful drug (doxepin) for me so far. Been about 3 months now."

• Ano...
• Taken for less than 1 month
• November 2, 2019

"I've been on doxepin 10 mg for insomnia and anxiety attacks. In only three days, it has changed my quality of life for the better. I take it at 9 PM, and I’m asleep by 10:30 or 11 PM at the latest. I sleep all night. I do feel a little groggy in the morning, but it goes away after an hour of moving around. It keeps me centered and functional throughout the day. No anxiety or panic. It has relieved my palpitations too. A bit of dry mouth, but my pharmacist suggested I drink water or suck on ice cubes. It relieves the dry mouth. I was put on sertraline 50 mg and buspirone before this, and that combo totally messed me up. They caused me mild serotonin syndrome (rapid heart rate and high blood pressure). I’m so glad my doctor put me on doxepin. It has helped so much! I will not touch sertraline or buspirone ever again."

• fay...
• November 20, 2015

Doxepin "If you're not able to take or no longer able to take SSRIs, SNRIs, and Benzos, this is a drug to consider. I've taken it off and on for decades. It helps tremendously in maintaining normalcy and is excellent for someone deprived of sleep. Takes time, but once adjusted, it will become less of a problem. Although it will continue to help for a good night's sleep. It's best to take this medication later in the afternoon until you do adjust. God bless."

• Anonymous
• Taken for less than 1 month
• January 25, 2017

"I started doxepin last night, and I have insomnia and wake up several times during the night. I slept from 6:30 PM to 7:30 AM, but I'm still a little tired today, however, I didn't wake up once. So, so far so good. I think I'm going to be very pleased with this drug. It also helped a lot with my anxiety as well. I've had zero side effects so far, and hopefully, I won't have any. Good luck to everyone that takes it, because for me, after trying several meds, this seems to be the best one so far and without weight gain, too. Most insomnia medications cause weight gain based on the research I've done, and this one doesn't, thank God, because I've just lost 110 lbs and do not want to put any weight on now that I'm at my perfect weight for my height. I hope this helps."

• Kel...
• Taken for less than 1 month
• February 24, 2015

"Especially good for helping you stay asleep! The problem is that I slept 12 hours straight and most of the next day. I didn't really have an issue staying asleep before-my issue is more with relaxing and going to sleep at appropriate times. So, if you have a lot of trouble staying asleep, this definitely works. No terrible side effects, I was just very sleepy. If you really need the sleep, go for it!"

• Bri...
• Taken for 6 months to 1 year
• June 8, 2019

"This drug doxepin has definitely decreased my anxiety and panic attacks. After years of trying nearly every drug out there, I've finally found one that works well (for me). The one downside I have with this drug is the grogginess in the mornings. However, I've been running in the morning to help ease the grogginess, and it certainly helps."

• No ...
• September 24, 2017

"I have been on doxepin for many years for panic attacks. Before this medicine, I stopped going out anywhere. You will be tired for a bit of time, but it goes away. It stopped all panic attacks. Never had one panic attack for 10 years on this medicine. But I stopped to try other meds for a higher mood. But when I stopped doxepin, the panic attacks returned, so 10 years without a panic attack on doxepin is a good thing!"

• Nic...
• June 8, 2013

"Psych keeps trying to replace Klonopin and Ambien with doxepin. It is very dose-dependent. Prescribed 50 mg but take 10 mg, splitting capsules. Great sleep helps with anxiety the next day but is sedating. Non-habit forming - no real 'good' feeling. Took it last night and it worked great for sleep and anxiety. Will see how today goes."

• Anonymous
• Taken for less than 1 month
• April 16, 2019

"I started on doxepin 75 mg 15 days ago. I have noticed a decrease in my anxiety, excitability, and obsessive thinking and thoughts. I used to have a problem sleeping. Not anymore!! I am asleep in about 20 minutes, and I stay asleep. I used to be such a light sleeper and never got more than 5 hours of sleep. I used to take Gabapentin for nerve pain. However, I haven’t needed it since taking doxepin. I noticed it also takes my appetite away. Now for the horrible side effects... I have to force myself up. It takes me a few hours to fully be awake. I was in a horrible brain fog for the first 10 days. The first four days I felt like I had the flu. Now I am still dealing with the tiredness. I don’t want to stop it. However, I will if the tiredness doesn’t subside. I am glad I have had no headaches on the medicine, as other meds have given me."

• sop...
• Taken for 10 years or more
• January 31, 2024

"I developed Tardive Akathisia from the antidepressant, Amoxapine. It was the most horrible feeling I could ever imagine! It is not a natural feeling. It feels like you are jumping out of your skin, with extreme fear and dread, like everyone on earth had died. For two years, I was given many different medications and none of them worked. Some made me way worse. I was losing weight and had a hard time eating and sleeping. I found a better psychiatrist and was put on Doxepin. I immediately felt relief! After three days, I was completely back to normal. That was 1988 and I was put on 150 mg before bed. It got rid of my insomnia and seizures also! I am on the same dose since 1988 and it has given me a wonderful life. I tried to gradually get off of the Doxepin, twice, but I went back to the same horrible symptoms. I have permanent Tardive Akathisia. I am SO grateful for the Doxepin!!"

• Buf...
• June 23, 2014

"My doctor prescribed me Doxepin 10 mg for depression, anxiety, and insomnia. So far so good, calms me down wonderfully when my three kids or my husband cause me to have an anxiety attack, and is working well with my depression. Only things it isn't doing too much for my insomnia, I still go to bed at about 9 PM and fall asleep around 2:30-3:00 AM. I have also taken Lexapro, which worsened my depression, Zoloft just made me feel like a zombie or like I was wired out of my mind, and Prozac, which worked great on me, but since I have insomnia my doctor gave me Doxepin."

• pcw...
• Taken for less than 1 month
• June 7, 2019

"Was on Doxepin many years ago and did not have one anxiety attack or panic attack at night when they mostly happened. Then I went off it. Today, I am back on it, 25 mg at night. I do not know why my doctor took me off it. I am now back on it, so here's hoping. Will let you know how things go."

• Anonymous
• May 2, 2010

"I have been taking Doxepin for 26 years to treat depression and acute anxiety. It has worked well and enabled me to feel normal and lead a normal life. Recently, though, it has stopped working as well, and I am having panic attacks and anxiety again. I think I have become immune to it because of taking it for so long. Would like to switch to a newer drug, but my doctor is not keen to swap me."

• met...
• September 17, 2016

"This drug was terrible. I would take it at night and fall right to sleep, and when I got up in the morning, I'm completely exhausted and dizzy. My balance is off and I feel like I'm in a daze. I was extremely irritable. The entire day I was depressed and in a very, very bad mood. Everything bothered me. My anxiety was terrible. Tremors in my hands and just feeling kind of loopy. Nightmares when sleeping. This drug did nothing of any benefit for me. I was taking it to help with my social anxiety and panic attacks."

• rig...
• October 10, 2017

"I have suffered with severe anxiety and panic attacks, which manifested itself into not sleeping. I literally stopped sleeping for several days. Ended up in the ER a couple of times and at the doctor's all that week and finally had to be admitted to a mental health facility because nothing they were giving me was working. I literally thought I was going to die. After 9 days, they finally found something that helped me sleep. It was a combination of Doxepin 100mg, Xanax, Tramadol (which soon switched to Benadryl) and Ambien. These drugs gave me my life back and slowly restored my sleep cycle. After a year or so, I was weaned off the Ambien and then the Benadryl, so now I just take the Xanax & Doxepin (now lowered to 50mg). Amazing."

• BBP...
• Taken for 6 months to 1 year
• December 2, 2017

"Started on Doxepin 100 mg in January 2017 due to debilitating GAD and panic attacks. I was miserable. Ten minutes after waking up, the panic attacks would start. I quit going out in public as much as possible. At night, I couldn't shut my mind off, which exacerbated my insomnia. I was taking more Xanax than prescribed to try to get through the day. I specifically asked my psych for this based on reviews. Helped right away with sleep (with no next-day grogginess for me), and after about a week, started putting the brakes on my anxiety. Slowly noticed I was getting parts of my life back. It served its purpose and pretty darn well, but in ten months, I gained 30 lbs and kept gaining. Due to the ongoing weight gain, I switched to gabapentin instead."

• mil...
• Taken for less than 1 month
• September 1, 2017

"I was prescribed Doxepin for anxiety, panic attacks, and depression. I took it last night and slept great, but this AM I could NOT open my eyes, and all day I have been beyond drowsy, even spaced out and exhausted. I took 10 mg at bedtime last night. I am going to try taking it at dinnertime tonight around 7 PM. I am glad I slept great, but I cannot function on this exhaustion. Please tell me these side effects go away. Also, could one pill do all this? Last night was the first time I tried this :-(. Thanks"

• Tri...
• Taken for 10 years or more
• March 19, 2025

"I have used doxepin for 30 years for general anxiety and insomnia. Many doctors over the years have tried to wean me off it and onto a more modern drug. With disastrous results, including admission to the hospital. As soon as we get off the other thing and back on doxepin (pretty low dose, 25 mg), I go back to being myself."

• Kge...
• June 2, 2021

"I have been suffering with anxiety, depression, and insomnia, but doxepin helped me get my life back. Thank you to those who created this medicine. My concern is how long will I take this medicine? Is this going to be for life? I am thinking of asking my doctor. It really helped relieve anxiety and depression. I take it right in bed, and it works well. 9/10."