Skip to main content

Donepezil for Alzheimer's Disease User Reviews (Page 2)

Brand names: Aricept, Adlarity, Aricept ODT

Donepezil has an average rating of 4.9 out of 10 from a total of 69 reviews for the treatment of Alzheimer's Disease. 39% of reviewers reported a positive experience, while 43% reported a negative experience.

Reviews for Donepezil

  • Furni...
  • August 29, 2007

Aricept (donepezil) "Mom was having memory problems and was prescribed this drug. By the 4th week on the drug, she was having delusions. It's been 6 months and the delusions seem to be reduced, but not gone. Caffeine seems to add to the problem so we are reducing her coffee. She also seems to get better when she exercises (walking)."

Was this helpful?YesNo
162 Report
  • Anonymous
  • Taken for less than 1 month
  • March 24, 2021

"My poor mom was up all night with bad nightmares and talking all night in a state of confusion. Today she is like a zombie with no appetite & refuses to get out of bed because she is so tired. I should have looked up the side effects first. I am livid with the Dr. that prescribed this"

1 / 10
Was this helpful?YesNo
46 Report
  • Cajun...
  • September 21, 2009

Aricept (donepezil) "My mother was on this as well for 6 weeks when the delusions started. The pharmacist said that it would take a little while to get out of her system. I did see a major improvement in her short-term memory! Maybe the drug makers could alter the recommended dosage to once a week since this seems to be a buildup before we see the delusions happen. I didn't want to take her off of it because of the improvement, but I did not want her to continue to wander out of the house because of the voices she was hearing."

4 / 10
Was this helpful?YesNo
141 Report

Frequently asked questions

  • berta
  • Taken for 1 to 6 months
  • June 27, 2019

Aricept (donepezil) "My MD tagged my DL (drivers licence)when she prescribed this med. When I asked why she said "we report every prescription of this med to the DMV." So (age 71) I took the written test and am scheduled for the road test. Proctor said "you did VERY well!" on the written test! Not too worried about the driving test (my 40 YO niece says "you drive better than I do!"). So be forewarned. Drug well tolerated, no issues. Is it doing anything good? Who knows?"

5 / 10
Was this helpful?YesNo
58 Report
  • daugh...
  • Taken for 6 months to 1 year
  • October 21, 2015

"My mother was on this and had negative side effects, diarrhea, weakness, changes in behaviors, combative, using foul language, on 10 mg. I complained, and the MD took her off, then put her back on 3 months later, same side effects. I am disgusted at how these meds are prescribed, and the side effects are WORSE than the behaviors. I am an RN, and this is abuse of our elder patients."

1 / 10
Was this helpful?YesNo
83 Report

Are you taking this medicine?

  • Sandy...
  • November 4, 2015

"Mum has first stage Alzheimer's and was put on drug 8 weeks ago. She has gone from someone who was pleasantly confused, is now incontinent, won't eat or drink, sleeping all the time, and is now in hospital because she was found unresponsive! Had been examined by 4 doctors within the 8 weeks who all said she must stay on the drug! Even though it was blatantly obvious to the family, it was the drug causing the symptoms! The drug was stopped 2 days ago and she is alert and talking."

1 / 10
Was this helpful?YesNo
79 Report
  • just...
  • Taken for 1 to 6 months
  • January 21, 2023

Aricept (donepezil) "Neurologist prescribed Namenda. Too many side effects. Went on Aricept and was more confused, diarrhea, stomach cramps, resting heart beat 90, couldn't sleep. Excessive crying was frightening. No reason to cry. I came home one night and was planning a suicide attempt, crying and exhausted. I stopped taking it immediately. I have never had a thought about suicide. Very frightening. I'm a 66 y.o. woman with dementia. I did not experience anything positive with this medication."

1 / 10
Was this helpful?YesNo
20 Report
  • Teeps
  • Taken for 1 to 6 months
  • January 12, 2020

"My first experience with Donepezil 10mg was nasty, It affected my sleep in a bad way and made my memory, speech and basic cognitive functions worse and I was continuously lethargic. After 2 months on the drug I can honestly say I feel a huge difference (for the better). There is a big improvement in both my memory and speech and it's really made a difference in my day to day life and daily tasks ."

7 / 10
Was this helpful?YesNo
43 Report
  • Tahs
  • August 24, 2017

Aricept (donepezil) "At 78 my husband started on aricept 10mg for increasing symptoms of Alzheimer's . He did well for a long time . Memory improved. When he stared to decline again months later he was put on namzaric. Did great again for many months. He now has had increase in aricept. Showed improvement. Again. Wishing this would last."

Was this helpful?YesNo
57 Report
  • Anonymous
  • Taken for 1 to 6 months
  • October 27, 2016

"My 65 yo husband started the 1/2 pill regiment 5 weeks ago. Big improvement in conversations, no longer accusing people of stealing from him. Than we had to wait 5 days for the prescription to be refilled. That was a decline, back to talking to imaginary people, aggressive behavior, no energy. Now he is on the whole pill. Wow, almost back to being pleasant. He takes his in the morning, so no sleep interrupted. Energy back, never had a side affect as far as loss of appetite, weight loss, diarrhea. Early stage of ALZ/ Dementia. Glad he is doing better, still a day to day."

9 / 10
Was this helpful?YesNo
57 Report
  • yogiman
  • July 16, 2008

Aricept (donepezil) "After brain surgery, my vocabulary and speech became very bad. A doctor suggested Aricept. I didn't notice any improvement in my speech, but my kids did. Apparently, it works for different things. Because of the surgery, my short-term memory is out. Long-term memory is still there."

8 / 10
Was this helpful?YesNo
97 Report
  • Think...
  • September 24, 2015

"Mom is on this stuff just a short time now. Put on 5 mg, then 10, now to 20/day in an 8 week span. Her confusion got much worse, daily nausea set in no matter if taken with meal or not, sleep pattern really changed and attitude became combative and nasty. I am weaning her down to 10 mg/day and if no change I will take her to 5 then stop all together. This stuff may work for mild cases of alzheimer's but not for my mom"

1 / 10
Was this helpful?YesNo
59 Report
  • Leisure
  • Taken for 1 to 6 months
  • August 10, 2018

"My 82 year old mum was diagnosed last year with Alzheimer's Disease. We really noticed her decreased language skills. She couldn't remember words for things. Could only chat with me for 10 minutes before she had enough. Also tired and not interested in much. Her writing was terrible. She started on 5mg and is now on 10mg. She saw people in her room (that weren't there) when she first started but taking tablet in the morning helped that. Her language has improved immensely. Chats to me on the phone for an hour with hardly a stumble. Is interested in things again and wrote a list of questions to ask her dr without a problem. She even renewed her passport and is going on a cruise to NZ in November with her friend! Don't know how long it will last but we will take what we can get! The only thing I've noticed is she gets a bit cross with her partner especially if he doesn't let her do things herself. She is aware of this."

9 / 10
Was this helpful?YesNo
43 Report
  • Bird
  • Taken for 1 to 6 months
  • March 26, 2018

Aricept (donepezil) "I was taking Aricept to help preserve my memory, due to the fact that I am 46 yrs old. I had brain surgery in 2009 to prevent seizures and now my memory is very bad. I took this medicine for about 2 months, but the vivid dreams and leg cramps were just too much to handle. I am trying a new Alzheimer's medicine now. I believe every medicine has side effects, we just have to pick and choose!!!"

5 / 10
Was this helpful?YesNo
45 Report
  • KMP
  • Taken for less than 1 month
  • November 2, 2022

Aricept (donepezil) "My dad was diagnosed with dementia and was prescribed Aricept. His demeanour changed to extremely agitated and almost violent. I had to stop giving it to him. It did nothing to help with his memory. I saw only negative impact on him from taking this drug."

1 / 10
Was this helpful?YesNo
17 Report
  • Marram
  • August 31, 2016

"My mother in law was on this drug for 2 months. While her short term memory continued to fail she also seemed more confused. We took her off and she has started to seem less confused-this is week 3 without. She has also experienced diarrhea and had lost weight. I am not sure there is a reliable study that can tell how well this drug might work for some because everyone's disease is different. We can't go back and see how they would have done without the drug. We will not be putting her back on."

2 / 10
Was this helpful?YesNo
46 Report
  • Anonymous
  • Taken for 1 to 2 years
  • August 12, 2012

"Our Mother has been on this medicine for sometime now and not sure if it's helping or not. She gets angry all the time and see's things and people. Whats to go home even when she is home and doesn't understand why she can't see her family. She seems to be stuck at this stage and isn't moving forward (not getting better not getting worse). She is losing weight and not sleeping and falling a lot. Don't know what to do, take her off or leave her on it. "

2 / 10
Was this helpful?YesNo
62 Report
  • Anonymous
  • Taken for 1 to 6 months
  • October 4, 2017

"I took my father off this medicine. Really awful side effects, he had a hard time controlling his bowel and it wrecked havoc on his extremities. The drug caused all his hands and fingers to lock up and he also experienced really painful cramps on his legs and feet."

1 / 10
Was this helpful?YesNo
32 Report
  • NCdau...
  • Taken for 1 to 6 months
  • August 27, 2017

"My dad has been on it for about five months, and he has mild dementia. Normally slow to anger and hates confrontation. He is in his nineties, and after taking the medicine says he needs to be 'locked up' because he is afraid he will do something terrible. Bad nightmares, irritability and some muscle pain. Told him to throw the stuff out and we will see if there is improvement."

2 / 10
Was this helpful?YesNo
30 Report
  • Lynda...
  • July 15, 2017

"My mum has been on Donepezil for 2 years. Over the past 6 months her appetite had deteriorated, she's losing weight, getting aggressive and she was falling a lot. I have recently discovered she wasn't taking her pills and hiding them in her gums and pretending to swallow, then when I moved away she was taking them out of her mouth and putting them in the bin. She's 82. I have changed the routine of night time meds to morning as this seems easier. Without this pill, 10mg a day, she deteriorates badly. There is a massive difference in her vocabulary and attitude more than anything else. For those bad comments talking about the drug when it hasn't been taken for at least 12 weeks, please ignore. This needs to be given time to work."

9 / 10
Was this helpful?YesNo
30 Report
  • jkano
  • Taken for 2 to 5 years
  • August 23, 2018

"My husband was put on donepezil about 5 years ago, he was started on 10 mgs but he started to be unsteady and fell a few times, he was then put on to 5 mgs and has been on this nearly the whole time, however, he was diagnosed with Asthma and then COPD, he was extremely unwell for over a year and I thought he was going to die. I consulted with his doctor and we agreed we could try stopping the Donepezil, that was nearly a year ago, although he still takes medication once a day for the COPD it has never come back, his memory is poor but he is still active and thankfully no recurrence of the breathing problems."

1 / 10
Was this helpful?YesNo
26 Report
  • Deser...
  • Taken for less than 1 month
  • March 19, 2024

"I am writing this for my husband. He was recently diagnosed with Alzheimer's. During our visit with his neurologist last week, I asked if we couldn't consider some kind of therapeutic treatment. The doctor offered Donepezil. I had never heard of it. He started him on 1/2 pill per night for 30 days, then will increase to 1 full 10mg tablet after that. I have to say - I am so extremely impressed so far with how much this medication has helped him. I started noticing a huge difference by the 2nd day, and by the 3rd day, he was smiling again and even making jokes. He hasn't done this for over a year. He is more 'present' and more aware of and interacting with his surroundings. He is talking in complete sentences. He isn't getting angry with the dogs and cats. He is actually engaging in discussions with me again. He was even able to read some simple instructions to put together an item I bought him for Christmas. He hasn't been able to use tools for over a year. I'm so grateful."

10 / 10
Was this helpful?YesNo
3 Report
  • Anonymous
  • Taken for 2 to 5 years
  • December 21, 2015

"My wife has taken Donepezil (first 5mg then after a year 10mg) for some three years. Initially her Folstein MMS score was 28/30 and is now 17/30. She has no apparent side effects. I cannot tell what my wife would be like without it - now her forgetfulness is almost instantaneous and she is now incapable of independent living."

5 / 10
Was this helpful?YesNo
29 Report
  • Son
  • Taken for less than 1 month
  • December 22, 2022

"Don’t use this. Immediate negative side effects for my 87 year old mom. No appetite led to weight loss. Also, she had depression, constant crying and anger. Stopping donepezil saw immediate improvement"

1 / 10
Was this helpful?YesNo
8 Report
  • Caper...
  • Taken for 5 to 10 years
  • May 11, 2016

"Very good results for my mom w/vascular dementia figure it gave 3-4 more years with her still cognitive some can take w/results some not so much we were able to travel better after this medication for sure"

8 / 10
Was this helpful?YesNo
26 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Alzheimer's Disease

Symptoms and treatments

Medicine.com guides (external)