Dextromethorphan / quinidine for Pseudobulbar Affect User Reviews

• Bel...
• August 29, 2015

Dextromethorphan / quinidine "I have MS and my mood swings were unbearable. I feel like this drug has balanced out my brain. Not only am I no longer sad and suffering, I think more rationally. I am going through a very stressful time in my life. Normally, I should just want to lay in bed and cry. This drug has put me in control of my emotions! I have tried a variety of antidepressants. They made me feel numb. I hated them. This drug is different! I also have a history of self-medicating with alcohol to cope with my anxiety when a very stressful situation occurs. Since I have started this med, I have no desire or urge. I'm not one to get online and write a review. But I feel like this is helping me live again. And I want to share the word!"

• ano...
• August 15, 2011

Dextromethorphan / quinidine "It has been about two weeks since I've been taking Nuedexta. I went to my doctor back then as I was having angry outbursts as well as increased thoughts of hurting myself or others. Additionally, my anger was taking over any type of rational decision making. My doctor prescribed Nuedexta...just more recently, I've felt somewhat of a change. I don't feel as angry and if I'm in an anger-provoking situation, I know I have to 'step aside' and take time out. This never happened until I took Nuedexta. The only complaint I have about the medicine is that since it's new on the market--as far as I know, as the pharmacist had never heard of it--the cost was high and I had to wait a day for the prescription to be delivered."

• Anonymous
• November 16, 2011

Dextromethorphan / quinidine "I suffered a bilateral subarachnoid brain hemorrhage and am happy to be alive. However, one of many hurdles left behind for me to deal with was laughing at inappropriate times and crying at the drop of a hat. My brilliant Doctor prescribed Nuedexta. I have not had an outburst since taking the medicine and no side effects at all."

• Anonymous
• October 19, 2011

Dextromethorphan / quinidine "Diagnosed with a paraneoplastic neurological syndrome that has been progressive. Latest development was extreme mood changes and sudden outbursts. After one week on Nuedexta, I felt much improvement. Had to stop during the third week due to infection (I am immunodeficient due to chemo) and the antibiotics I was taking. Fell back into prior symptoms. Now into the second week retaking and positive effect is the same as the first time around. The difference is remarkable."

• CKG...
• Taken for 1 to 6 months
• August 30, 2014

Dextromethorphan / quinidine "Sustained a traumatic brain injury (TBI) and subsequently had a stroke. I was depressed about the sudden limitations of what I could do after the TBI. I was on the antidepressant CYMBALTA, which had no effect. Within 7 days of taking Nuedexta, I did not feel as hopeless. I had been very much an A-type personality and practiced as an attorney prior to my TBI and subsequent stroke. I had great difficulty in suddenly having limitations regarding what I was able to do, my memory, and executive function. I am grateful I was referred by my neurologist to another neurologist who specialized in TBI. Not many physicians, including neurologists, have a proper understanding of traumatic brain injuries, let alone how to treat them. The price REALLY should be lower."

• Gra...
• Taken for 1 to 6 months
• May 8, 2013

Dextromethorphan / quinidine "After my dad was finally diagnosed with dementia/Alzheimer's, he went through aggressive behavior and tried to hurt himself. Risperidone helped with the aggression, but the constant yelling and crying started. After lots of trials, the doctor prescribed Nuedexta, which took away most of the yelling and crying. He is more alert and thinking more clearly. We are truly happy to be able to visit and enjoy our time together."

• Anonymous
• Taken for 6 months to 1 year
• August 29, 2012

Dextromethorphan / quinidine "This medicine has changed my life. I suffer from rapid cycling bipolar. My up-and-down mood swings had been well controlled with valproic acid, but I was left with spontaneous crying jags. It was so frustrating to be completely unable to control my outward emotional appearance. It's hard to be taken seriously at work or find a new job if I look like I'm having a total breakdown. Internally, of course, I know this will be over in minutes, and I don't feel any emotion about it at all except intense embarrassment. I found I started to avoid situations I couldn't predict. After about two weeks on this medication twice a day, my crying stopped. I feel like a new person. I am so much more confident about going about my daily life."

• Taj...
• Taken for 1 to 6 months
• March 31, 2015

Dextromethorphan / quinidine "I have MS, and hadn't even considered that it was affecting moods, such as anger and constant crying. I've been taking Nuedexta for approx. 3 months now. It has helped me exponentially! Now I no longer cry all day, and I don't often yell! Nuedexta really smoothed things out for me!"

• Deb...
• January 28, 2014

Dextromethorphan / quinidine "This medication addressed inappropriate crying and laughing that has plagued me since a right frontal lobe aneurysm rupture 10 years ago. Took a few weeks to adjust to the side effects but well worth the effort!"

• riv...
• Taken for 1 to 6 months
• April 18, 2016

Dextromethorphan / quinidine "I started Nuedexta almost two months ago due to severe mood swings, angry outbursts, and frequent crying episodes. Thanks to this medicine, these behaviors have pretty much stopped. I do think for two generic drugs that the price should be lower."

• Tak...
• January 11, 2021

Dextromethorphan / quinidine "My wife suffered multiple strokes, and after we discovered she also had the crying and laughing syndrome everyone here is talking about. Life without Nuedexta is awful, there is constant crying and uncontrollable laughter to the point I worry about her blood pressure. My only complaint is the cost of this drug, out of pocket, it is nearly $1,300.00 for our 90-day prescription. After much research about possible generic drugs, I found that the patent won’t be up until 2024 or something like that. The good news is that it’s made up of basically the same substance as a Walgreen cough pill called Wal-phen, the same exact ingredient, except without the time release, which basically tells me I had to try multiple pills instead of one. So, at the cost of $8.99, I tried it, and it actually works. So we now take 2 Wal-phen in the mornings and 1 regular Nuedexta at night, and everyone’s happy."

• Rin...
• Taken for less than 1 month
• August 26, 2018

Dextromethorphan / quinidine "I took this medication for PBA after a brain stem stroke. It seems to get good reviews, but it was not the case for me. Lost all of my energy and enthusiasm. Made me so depressed. Seriously. Stayed on it too long because I was looking for a good result. Seemed to work so well for others. Be careful."

• DMG...
• February 9, 2023

Dextromethorphan / quinidine "Greatest drug on the market. No brain trauma, just severely depressed for over 30 years. Cried all the time. Never felt like a normal human until I went on Nuedexta. Now, after 3 years on it, new insurance won't pay for it. Nothing else like it, so I have to stop. I am dreading my life not taking it."

• tai...
• Taken for 6 months to 1 year
• June 11, 2020

Dextromethorphan / quinidine "I started using Nuedexta after I had a stroke and had excellent results. I was covered with insurance, but now do not have insurance, so I cried when I was told the price for the script was $1,200. I almost had another stroke."

• tea...
• Taken for less than 1 month
• January 19, 2020

Dextromethorphan / quinidine "Feeling numbed out by this medicine. Probably why it seems to work. I unfortunately have other conditions it won’t treat that the meds for conflict with it. I am still feeling rage and sadness. I’m not sure what to do next. I guess talk to my doctors."

• Rad...
• Taken for 6 months to 1 year
• August 13, 2022

Dextromethorphan / quinidine "Nuedexta has changed my life for the better. It took 17 years to get a real diagnosis for a neurological illness. 12 years ago, I experienced PBA, unfortunately, the medical department thought I was crazy, and the journey began. I have taken many drugs for mental disorders, they made everything worse. The fevers, body aches, muscle stiffness, just outright torture. Now that I am diagnosed correctly and am on treatment, I asked my doctor for Nuedexta for mood shifts and an inability to stop crying. It changed my life and made my mood stable. No more drop-of-a-hat outbursts. As a side note, I hope this drug can be utilized more in the mental health industry to help those with anger issues. Mental health doctors I've talked to said they can't just prescribe it alone. What gives? So glad I have Nuedexta in my life."

• Anonymous
• Taken for 1 to 2 years
• May 14, 2014

Dextromethorphan / quinidine "I have been crying inappropriately since a stroke 2 years ago. Nuedexta has helped me keep my emotions in check. I still cry, but usually in more appropriate situations. Recommend it."

• liz...
• January 30, 2015

Dextromethorphan / quinidine "My mother has Alzheimer's disease, and lately she started crying and getting aggressive. This medication has controlled her behavior and her emotions 100%. Thank you very much."

• gri...
• Taken for less than 1 month
• January 24, 2016

"I feel horrible right now. Only day 2 starting meds, but massively depressed and totally drained, no energy."