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Desvenlafaxine for Anxiety User Reviews (Page 3)

Brand names: Pristiq

Desvenlafaxine has an average rating of 7.2 out of 10 from a total of 178 reviews for the off-label treatment of Anxiety. 67% of reviewers reported a positive experience, while 17% reported a negative experience.

Reviews for Desvenlafaxine

  • Anonymous
  • September 11, 2011

Pristiq (desvenlafaxine) "I have avoided taking medication for my anxiety/depression for about 8 years. I have been on Pristiq for 5 weeks now. The first 8 days were difficult. I had inner shakiness and found it hard to concentrate. I felt like I was off with the fairies. I wanted to stopping the medication but the doctor did warn me that I may have side effects for 7-10 days so I decided to give it 14 days and I am glad I did. For the first time in about 8 years I am the person I know I really am. Loving, forgiving, understanding, positive and most of all excited about life. Before this I was a nasty, negative person and stressed about everything. I blamed everything and everyone else for my life instead of taking personal responsibility."

9 / 10
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  • mommy...
  • Taken for less than 1 month
  • September 7, 2012

Pristiq (desvenlafaxine) "I've been on Pristiq for 2 weeks. I was on Effexor for 7 years after having my son. I always had anxiety and worry too much. After having my son I didn't know why I was panicking etc., all the time so they put me on 75mg on Effexor. It did good for me but I thought I'd stop. I stopped for 10 months and tried natural path which seemed to be okay but not the full strength. When my cat had to be put down almost a month ago I was a mess and still am. I begged my doctor to put me on something. I realize I need meds the most when something major has happened) so they said how about try Pristiq...LOVE IT. It makes me quite relaxed feeling for a few hours after I take it at lunch. My sex drive is SUPER HIGH."

9 / 10
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  • Anonymous
  • April 16, 2010

Pristiq (desvenlafaxine) "I'm a 20 yr old female with anxiety, panic disorder, and attention deficit. This was my first day of Pristiq, but I noticed a huge change today already! I took a 50mg in the morning before work and had no problem dealing with customers or talking to strangers in general. I had a few short moments where I felt nervous, but I was surprised to find I was very relaxed all day. I really had no idea I was so anxious all the time! I would definitely recommend this!"

10 / 10
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Frequently asked questions

  • Missb...
  • Taken for 2 to 5 years
  • September 1, 2017

"I had been taking Pristiq 50mg for sometime and felt great my anxiety, tiredness and sadness gone, with changes in our insurance I was given the generic Desvenlafaxine SUC ER 50mg, I noticed within a week I was feeling different. I continued to take it for three months and I feel like I am not taking anything, I brought it up to my doctor and he told me they are the same it's like the placebo effect. NO I disagreed with him they are different and I feel different. Do I take something else? I hate to start over trying different meds. Any suggestions?"

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  • MickeyO
  • July 22, 2013

"I too have been on many different Meds for depression and anxiety. Nothing worked so great as Pristiq, but you did not lose any time not taking this. This is a very new med out, and that is why we are all getting it now and having good reports. When it is approved it will be covered by your medical plan. It is the best thing that ever happened to me. I highly recommend it. Had no side effects."

10 / 10
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Are you taking this medicine?

  • kiwii...
  • Taken for less than 1 month
  • October 9, 2015

"I have been on pristiq for approx 2 weeks for anxiety and dizziness and disequilibrium. The first week was rough with sweating and a little nausea but no tiredness. From day 9 I have noticed a good boost in energy and a change in how I have been managing my anxiety with increased confidence and reduced dizziness. I will keep taking it but won't be looking forward to coming off it when the time comes. It has given me a new out look on life which is a big positive."

8 / 10
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  • happy...
  • Taken for less than 1 month
  • March 6, 2016

"After 5 years of altering my life to avoid anxiety and panic attacks and having tried many different types of medication I finally was given pristiq. I started 5 days ago and talk about a HUGE and almost immediate difference! Initially there were headaches (few days off and on) but instant energy and stable mood without anxiety! It's weird but things actually seem visually brighter and my sense of smell has increased. Appetite is down as smells are making my stomach churn so sticking with very bland foods and tons of fluids. Wide awake at night but that's normal for me. I am so grateful for feeling normal again!"

9 / 10
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  • Anonymous
  • September 2, 2009

Pristiq (desvenlafaxine) "I have been taking Pristiq for about three weeks now and it's been fantastic! I just feel normal again. I feel like I am back to my old happy, friendly self. I no longer feel panicked when I am in a very social situation and I'm not scared to try new things anymore. Overall I just feel very balanced. I can deal with stressful situations and get over them a lot more quickly. I don't dwell on them all day. I'm also a lot less cranky."

9 / 10
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  • Wal
  • Taken for less than 1 month
  • January 14, 2019

"Not good for me. After the first 2 days no real side affects. Day 4, couldn't settle. Walking around the house and garden feeling sick in the stomach. Day 5. Eight hours of on and off panic attacks. Night five, extreme anxiety all night. Day six did not take it and resumed to normal by the afternoon. Awful reaction. Never again!!"

1 / 10
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  • Anonymous
  • March 7, 2009

Pristiq (desvenlafaxine) "After trying several different medicines for anxiety, my doctor tried me on a trial run of Pristiq. I have been on it since May, and LOVE it! I don't have any side effects - except it may make me "too" calm."

10 / 10
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  • jaysc...
  • Taken for less than 1 month
  • September 22, 2012

Pristiq (desvenlafaxine) "i started taking 50mg just yesterday and immediately i noticed a huge difference. i have tried so many other antidepressants that were just awful on my system but this one so far seems to be great. i have noticed an immediate appetite decrease which is perfect since i tend to eat due to anxiety and depression. food just has lost its magic and a lot of its taste. but i still feel hunger which tells me it's time to eat, and i eat only till i am full. i have also noticed a slight tingling and twitching in my arms and hands, but only slight, and i am sweating more than usual. my jaw feels a bit tense as well, and all of these mild symptoms should go away once my body becomes accustomed to this new drug so i'm told by my doctor. happy times!"

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • June 20, 2012

Pristiq (desvenlafaxine) "I am a 19 year old female. I have been using Pristiq for over 3 weeks now. The first couple of days were pretty intense for me, I was very jittery, had a constant feeling of a ball being in the back of my throat, and was constantly thirsty. My second week was great, I started seeing very positive results. Pristiq really suppresses my appetite, but I've only lost a couple of pounds. Constipation is also another thing to be prepared for. I take it in the morning and it boosts my mood. I am also taking clonazapem for the night time. I would recommend this medication for people with mood disorders, but You have to be patient to see results. The first couple of days might frighten you a little, but be patient and see how you feel after a couple of weeks."

8 / 10
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  • Lennny
  • April 6, 2012

Pristiq (desvenlafaxine) "Great results on this medicine. The first couple of days I was a bit tired but that went away quick. My doctor prescribed it to me for general anxiety and not depression. So no crazy thoughts or ideas. I take it in the morning and that's it. No disruption of my sleep patterns. Actually I sleep like a baby. Very positive experience."

10 / 10
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  • Lily
  • Taken for 6 months to 1 year
  • August 25, 2020

"I had been struggling with increasing anxiety and depression for about 2 years. Very stressful work, and losing the two people closest to me in the space of 6 months didn't help. I have been on Fluoxetine before, and it worked well. My psychiatrist recommended I try Exsira (this is desvenlafaxine generic where I live). It's been amazing. I'm dealing with my still-stressful job a lot better. I'm more confident, and just feel so much better in general. Social anxiety is still there, but I can deal with that in other ways. My libido has dropped, but I just need to make a bit more of an effort to keep things going. My BF totally understands. The downside is if I forget a single dose, I get brain zaps. Very uncomfortable and annoying. Overall I'm very happy with it."

8 / 10
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  • Matt
  • Taken for 6 months to 1 year
  • February 7, 2024

"I spent a year from summer 2022 to spring 2023 suffering from bad anxiety and insomnia that was sliding me into deep depression as well. I tried Lexapro, Wellbutrin, Duloxetine, Trintellix, Mirtazapine, and Buspar and gave them a few weeks each to take effect, but with little luck. I tried 6 ketamine sessions in January/February 2023 that seemed to help me a little and give me a kinder, more productive February. Thank God I also had some Xanax available (about 1 mg/day) during this time. Finally tried desvenlafaxine in April 2023 (50 mg in the morning), and almost immediately noticed the anxiety and depression slowly going away. Felt 'normal' within a month. Here I am 10 months later, and I'm back to my old happy, productive self. And I had no problems quitting Xanax, luckily."

10 / 10
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  • Anonymous
  • May 22, 2009

Pristiq (desvenlafaxine) "I can only say good things about Pristiq. I was on Lexapro for about three years and gained about 35 pounds. My doctor switched me to Pristiq. The hardest part was weaning off the Lexapro and the couple of weeks it took for my body to adjust to a new medicine. It has been about a month now and I absolutely feel great, energized, my appetite seems more normal. I have lost three pounds in four weeks. Not bad since I wasn't really trying. The unusual changes I noticed at first on Pristiq was really weird dreams and sometimes at night I felt a little tense. But now I just feel great. Also unusual in my case, my doctor told me to take it in the morning but I was afraid of nausea so I take it at night."

9 / 10
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  • Lauren
  • August 15, 2009

Pristiq (desvenlafaxine) "I've been on Pristiq for two weeks. I've noticed a remarkable change in my energy level, mood and am no longer isolating myself. I am also more focused. I've lost weight on this medicine and had a dry mouth in the beginning. It does curb my appetite and after two weeks lost 8 pounds. I seem to be eating smaller portions. This medicine is definitely a wonder drug for me."

10 / 10
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  • pristiq
  • September 17, 2009

Pristiq (desvenlafaxine) "I suffer from extreme anxiety and severe depression. I have been on Cymbalta for a couple years and it makes me so tired. I couldn't take it anymore. I slept all day. I started Pristiq today around noon. I have noticed a boost in energy and can't stop smiling. The only side effects so far is blurred vision, a little jittery, sweating a lot but I haven't felt happier in years from one day!"

8 / 10
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  • Anonymous
  • November 10, 2009

Pristiq (desvenlafaxine) "I've been on Pristiq for about 6 months now, taking 50mg for about 6 weeks then bumping up to 100mg after that. I have noticed a huge change in mood. I don't fixate on little things and let them bother me for the whole day like they used too. I feel much more confident now and I am actually smiling lately. Some side effects I have noticed are the occasional headache (I find if I take it the same time each morning I don't get a headache), drymouth, and if I miss a dose I get absolutely WILD dreams and my anxiety comes creeping back in. Also, I notice it makes me ramble on and on when I talk sometimes which can be a little embarrassing especially in work situations. Overall though, the benefits significantly outweigh the side effects!!"

9 / 10
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  • Anonymous
  • January 2, 2010

Pristiq (desvenlafaxine) "This is the first medication I have taken in years that has actually worked in lessening my depressive episodes along with decreasing my anxiety. I have had no significant weight changes (which is important as I am also in recovery from Anorexia Nervosa). For the first time in so long I finally feel better! I am so grateful my Physician Assistant had me switch! Previous medicine: Zoloft, Cymbalta, Lexapro, Lamictal, Seroquel, Risperdal, Vistaril, Effexor. Current: Pristiq, Dexedrine, Klonopin when required."

10 / 10
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  • Anxiety...
  • Taken for 1 to 6 months
  • August 11, 2018

"I've been on this medication for about 2 months or so, maybe longer and I can tell you it doesn't do much. I have severe panic disorder and anxiety. I may as well not take the medicine if I want to be this miserable. I'm hesitant to come off since nothing seems to be helpful. I'm a 30 year old female and wish to have a life in which I can function and enjoy."

4 / 10
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  • Seeki...
  • September 30, 2017

"I've had mostly a positive experience with Pristq. Some nervousness but I think I'm still adjusting to it. I've seen several people post on the generic not being effective so before I started taking it I did some digging and discovered that Greenstone is a subsidery of Pfizer and they distribute an authorized generic. Authorized generics are the name brand repackaged as a generic. "

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  • Neshee
  • December 22, 2009

Pristiq (desvenlafaxine) "I was given this medication as a test of some sort. I had been in a abusive relationship and I was having issues with it. My blood pressure was sky high. My doctor gave me the blood pressure medication and she gave me the Pristiq as a means of calming me down and seeing if it would help me to lower my blood pressure. I can say that within the first week of taking this medicine I was a new person again. It helped me a lot and people even notice a new and happier me. I call it my "Happy Pill" and people really see that now I am Happy. My energy level is much better than it was before. Really good product. I just ran out of samples so now I am now asking my doctor to prescribe it to me permanently."

10 / 10
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  • Anonymous
  • October 1, 2011

Pristiq (desvenlafaxine) "I have bad anxiety, which was brought on by strokes I suffered in 2009 due to a hole in my heart. Pristiq has been wonderful. The first 2 to 3 weeks were hard but now I am reaping the benefits. No anxiety, lost weight and now finally have lots of energy. Stick with it and it will be worth it."

10 / 10
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  • Amob
  • Taken for less than 1 month
  • August 29, 2020

"Started this drug desvenlafaxine 5 days ago when I had my 2nd ever panic attack and I haven’t been able to sleep since. At first I thought it was my anxiety keeping me up but it was the side effects of this drug that has only made my anxiety worse . I warn those this seems to be a strong drug and don’t be tempted to get on it after your first anxiety attacks. I plan to get off of it but I am terrified that my body will react to the removal of this drug from my system. I'd rather have an anxiety attack than to feel like a zombie at 4am struggling to sleep. My doctor said I can wean off of it after a year but I have yet to read about someone successfully do so."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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