Desmopressin User Reviews & Ratings

• She...
• June 18, 2009

Desmopressin for Primary Nocturnal Enuresis "My daughter is 8 years old now. She has suffered from bedwetting for the past 2 years. We have tried everything under the sun to help with the problem. She was so embarrassed when she would go to sleepovers and had to wear a 'pull-up'. I felt awful for her. I took her to the doctor, and he referred her to a urologist soon after. Her urologist put her on DDAVP almost 3 weeks ago. She takes 0.2 DDAVP every night about an hour before she goes to bed. We have been dry ever since, except the first night of taking the DDAVP. I believe this medicine is a godsend. My daughter is so happy, she is no longer embarrassed about wetting. We went yesterday for a follow-up with the doctor, and everything is going great."

• Ric...
• Taken for 1 to 2 years
• August 12, 2019

For Nocturia "After having prostate cancer and radiation treatments, it affected my bladder. I was peeing 3 to 4 times a night, like a newborn, so I went to my doctor, who prescribed the nasal spray desmopressin. Close to bedtime, I cut back on water, I use one spray, and about 15 min later, I get sleepy and only wake up one time a night. Yes. But I don't know why I wake up with a headache. Although I still use desmopressin."

• Sky...
• January 4, 2021

For Diabetes Insipidus "I was diagnosed with diabetes insipidus at 6 but was born with it. Was malnourished for years because all I wanted was fluids. A doctor finally figured out what was going on when I was 6. DDAVP can be a godsend, but the headaches I’ve seen others experience are because the medicine lowers your sodium. Therefore, you have to be careful about fluid intake. I also saw someone mention something about exercise, I would recommend not taking it right before any exercise (because that naturally will lower your sodium) and then take it later in the day when you start peeing a lot again. Give it about a month to adjust. Any new exercise regimen or diet change or really anything that could affect sodium and my medicine takes me about a month to adjust to. I love DDAVP because it gives me a more normal life than I would’ve had, but you do have to be careful with the dosage and fluid intake. I would not be on it if I didn’t have to be."

• Anonymous
• Taken for 5 to 10 years
• May 17, 2023

For Diabetes Insipidus "I take desmopressin because I had a brain tumor that destroyed my pituitary gland. I take three of the 0.1 mg pills morning and night. My morning dose works great with little to no complications, but it seems like my night dose, if I drink any more than a bottle of water before bed, I need to use the bathroom every 20-30 minutes from halfway through the night. I haven’t quite figured out the med yet, and I’ve been on it for 6 years."

• Lee...
• Taken for 6 months to 1 year
• March 8, 2020

For Diabetes Insipidus "I have been using desmopressin spray for complications resulting from a giant pituitary tumor, and it worked great (10+) to keep me from urinating every 10 minutes and controlled my unquenchable thirst. However, after about 6 months of using the spray, my nose has become raw, bleeding, and crusty, and I have been forced to go back to using the desmopressin pills, and they don't seem to work at all. (1-)"

• Ric...
• Taken for 1 to 2 years
• November 23, 2020

For Nocturia "I use desmopressin at night. It does cut back on going to the restroom. I sleep more, but when I wake up, I have a headache, like I feel like I have a hangover. So it looks like I'm going to stop taking desmopressin and slow down drinking water early."

• Dia...
• July 12, 2015

For Primary Nocturnal Enuresis "I can remember the first time I wet the bed, and for years it was almost every night, and I could never get rid of it. When I was around 15 or 16, I got this medicine, and it immediately stopped, and only once or twice did it happen again. But after I was finished with my prescription, I never needed it again, and I haven't wet the bed ever since."

• Han...
• August 4, 2021

Desmopressin for Diabetes Insipidus "I was one of the people testing in early 1970 Minirin as I have a familial diabetes insipidus. I was amazed that the first time in my life I don’t feel thirst, nor do I have to visit the toilet extremely often. Since Minirin was introduced in the market (about 1974), I have been using that nasal spray. Probably I’m at the age of 74 the oldest person on that medication. No problems whatsoever up to now."

• Jen...
• June 5, 2015

Desmopressin for Diabetes Insipidus "I've been on this since 1989. The generic pill form works best! Before DDAVP, I went to the bathroom around the clock and drank tons of water. The nasal spray was difficult at first since they didn't have my dosage right, which I ended up in the hospital with my sodium at 119. But after the doctors got the dosage down and with the pills now, I've had no problems. Thank goodness for DDAVP."

• Isl...
• Taken for 1 to 6 months
• April 2, 2019

For Diabetes Insipidus "Been on 0.1 mg desmopressin at bedtime for initial treatment. Had been drinking 2 gallons of water a day and still thirsty, urinating almost every 20-30 minutes, literally destroying my life. Muscle cramps set in, started in legs and spread to arms, hands, and feet. Then I started having electric shocks in my head, which is quite alarming. I'm sure I would have had seizures if I hadn't started treatment. Tremendous difference after the first night, I did not get up once to drink water or urinate. By morning, cramps were 90% gone and no head shocks. It was wonderful. Have to be careful how much water I drink a couple of hours before taking the medication at bedtime or my face will bloat. Figured this out after a couple of bad nights. Now working with neuroendocrinology on whether I could benefit from a second dose or splitting the current dose in two. This is a nasty disease that destroys lives. I'm grateful I got diagnosed and treated, but it was a long, hard road."

• HyG...
• Taken for 5 to 10 years
• February 9, 2025

For Nocturia "Nasal sprays all have greater exposure to the brain and may be the cause of the headache/hangover. A generic oral version of desmopressin is available and may reduce chances of headache/hangover. I take it every night and sleep through the night with the only side effect being greater sweating during exertion. Otherwise, after 5 years of use, have not had any other side effects."

• Wap...
• December 19, 2011

For Primary Nocturnal Enuresis "December 6th, I was finally able to sleep through the night and only woke twice to void. This is compared to sometimes every half hour or 20 mins, which I had been experiencing for the past six months or so. I was exhausted. Other medicines were ineffective, but Desmopressin has been a godsend. The only challenge I've had, other than the face flushing, is having to decrease my liquid intake despite needing the fluids due to the pain medicines I'm taking for metastatic breast cancer. I've noticed when I've ingested too much liquid, the Desmopressin doesn't work and I'm back to voiding upwards of 10 times a night, but just for that night. I'm very happy with the speed at which Desmopressin works as well."

• Tjc...
• Taken for 1 to 6 months
• October 22, 2019

For Diabetes Insipidus "Like someone else, I too used chlorpropamide for over 40 years. It worked perfectly. 1 tablet a day, and that was it. It just plain worked perfectly. I could even miss a day, and symptoms didn’t appear. Mylan stopped making the drug, and I had to switch to desmopressin about 3 months ago. Still trying to figure out the right dosage. It works but wears off in about 5-6 hours. Trying .2 instead of .1 now to see if that helps. What dosage are other people on? Did it take a while for you to settle on the best regimen for you."

• Anonymous
• Taken for less than 1 month
• February 26, 2020

For Diabetes Insipidus "Diagnosed a few weeks ago. On .1 mg in the morning and at night. No longer having horrible dehydration episodes in the night, which is great. I am, however, struggling to maintain the right fluid balance, particularly when exercising. I’ve had a couple of instances of low sodium from too much fluid retention, which you need to be careful of. Next step is to see if I can have a couple of alcoholic drinks when I don’t take the medication during the day but still take it before bedtime. Has anyone else found any successful strategies for exercising and/or drinking alcohol without issues whilst managing diabetes insipidus and desmopressin?"

• Anonymous
• October 13, 2022

For Diabetes Insipidus "I got diagnosed with diabetes insipidus a year ago, and I am taking desmopressin because of pituitary tumor surgery. It works at night, but during the day, I still go to the bathroom many times, and I start having face flushing and a light headache."

• DI2...
• October 21, 2009

Desmopressin for Diabetes Insipidus "I love this medication. It works fast and more efficiently than the pill form. After pituitary surgery, I struggled for 8 months trying to get my bladder activity under control. I could not control my urine flow with the pills, and if I was standing in line at the grocery store, there was nothing I could do but face the embarrassment of having urine stream down my legs. With the nasal spray, I can dose right there when the urge hits, and it sustains me for a few minutes until my situation is more conducive to taking care of things. The nasal spray is way more predictable than the pill. Thank God I have it, no matter what it costs."

• Tra...
• Taken for 1 to 6 months
• June 16, 2019

For Diabetes Insipidus "I started desmopressin nasal spray in February this year after taking chlorpropamide and hydrochlorothiazide for 35 years. It has worked wonderfully...never wearing off. I would almost forget I had a problem, but then the pharmaceutical Mylan stopped production, and here I am again. I was disappointed that they stopped making the rhinal tube, and I couldn’t get regulated. I’ve switched to the tablets and am trying to adjust the dose to last 12 hours. I’m finding that I have loose stools and now a bladder infection that I haven’t had in decades. I’m disappointed that the pharmaceutical companies only cater to profit as there aren’t many of us. I’ve searched all over for my previous meds, including Canada, without luck. My last meds of over 30 years gave me a very normal life."

• Eas...
• July 2, 2011

Desmopressin for von Willebrand Disease "My daughter is 16 and was diagnosed with Von Willebrand's when she was 13. I have found that it is the only thing that stops her menstrual bleeding. We have tried birth control pills to prevent her from having menstruation, but that didn't work. Without Stimate, she had bled for 7 weeks straight. She reports no side effects to me."

• fin...
• Taken for 10 years or more
• May 8, 2017

Desmopressin for Diabetes Insipidus "This is the easiest DDAVP to individualize. The spray only delivers 0.1 ml at a time, not good for people who only require 0.05 ml. The pill does not work... Period! Sadly, the manufacturer is discontinuing making the Rhinal Tube, which is devastating to people like me who will now face illness due to wrong dosing or inadequate dosing."

• Cry...
• Taken for 10 years or more
• February 5, 2015

For Diabetes Insipidus "Been on this medicine since I was 6 years old. Started on the nasal spray before the pill was invented. Found it hard to travel with because it needed to be refrigerated. Once the pill came out, I switched and never noticed a difference. Now that I am older and have a liver condition, my doctors told me to stop the medicine because it was helping my body retain water. Now I get very little sleep and drink like a fish even though I'm on a fluid restriction. Also, this med lowers my sodium levels as well due to the water retention. So if you're having some of the same symptoms, please see your endocrinologist for help."

• Anonymous
• August 25, 2010

Desmopressin for von Willebrand Disease "From my experience, it's worked amazingly well for my Von Willebrand's disease. It makes your face flush and heat very quickly, but it's not that bad of a side effect. The first time I used it, I was out of it for about 15 minutes, and after that, it never happened again."

• Lis...
• Taken for 2 to 5 years
• January 18, 2020

For Primary Nocturnal Enuresis "Our son, who is a bedwetter, took this from the age of 12 to about 14, and as long as he took the spray before bed, he did not wet the bed. If we were up at the cottage and forgot to spray, he would wet the bed, and we would have to get spray nearby."

• Caj...
• Taken for 10 years or more
• March 8, 2019

Desmopressin for Diabetes Insipidus "Been taking DDAVP nasal for over 15 years. Controls my CDI very well. Took Minirin before and pitressin tannate suspended in peanut oil before that. Was diagnosed with diabetes insipidus over 40 years ago."

• Anonymous
• October 21, 2010

For Diabetes Insipidus "I've been using desmopressin acetate injection for about 30 years, and it has been a lifesaver. The tablet form does not work as well as the injection, but it is easier to carry with me when traveling. The injection type must be kept in the refrigerator, but it is much more effective. I prefer to use the injection."

• ta ...
• February 28, 2009

Desmopressin for Diabetes Insipidus "I've been on the nasal spray nightly for 7 years since pituitary removal surgery. It's wonderful, expensive, but it works. I have found the generic version not as good, needs to be refrigerated, where the DDAVP has a normal shelf life."