Xiaflex for Dupuytren's contracture User Reviews (Page 2)

Xiaflex has an average rating of 3.8 out of 10 from a total of 39 reviews for the treatment of Dupuytren's contracture. 28% of reviewers reported a positive experience, while 69% reported a negative experience.

Reviews for Xiaflex

CP Au...
Taken for less than 1 month
September 15, 2021

"Had the injection and manipulation in June 2019. The out of pocket expense was considerably high. I had no adverse reactions and initially my pinky and ring fingers were not perfectly straight but I was happy. However after six months the pinky started to flex again and by 12 months was back to what it started at and is still becoming worse. Now at 90 degrees. Would never recommend this treatment."

1 / 10

Was this helpful?Yes No

3 Report

Ned
February 28, 2022

"Very effective. The secret is a good hand doctor. Completely satisfied with xiaflex which corrected a 90 degree bend in pinkie. Despite skin tear during follow up manipulation and the subsequent many bandage changes, it sure beats surgery."

10 / 10

Was this helpful?Yes No

2 Report

Andy...
Taken for less than 1 month
November 25, 2021

"Excellent results, although done early in progression with Right hand. 4th digit bent slightly near tip and 5th digit permanently bent and frozen at 1st joint. This condition had been progressing slowly over the past 12-18mos. I straightened and massaged on my own on 1st day after the procedure without numbing. I did not understand this would be done painlessly with numbing on the 2nd day. I heard large "pops" but with seering pain during this. I'll know better next time. But it seemed to be effective and I can honestly say I am 100% normal. I still have thick areas on my palm and between my 4th & 5th digit from when the MD split the skin after numbing and over-adducting these fingers apart. Left hand was too severely progressed and w/o attempting to use Xiaflex, surgery was performed. My 5th digit was unable to be straightened fully and over the past 5 years has regressed. 4th digit on left is slightly bent near the tip. I hope we can try Xiaflex on left hand."

10 / 10

Was this helpful?Yes No

2 Report

Frequently asked questions

Anonymous
Taken for less than 1 month
August 31, 2021

"Made my 2nd and little finger have a bend in them at the big middle joint that won't straighten out now. Overall fingers in right hand seem swollen on the underside and extremely sensitive to touch . My hand has lost the grip it had before the injections . Now I know why you can't get it from the USA into Canada any more. There should be a class action lawsuit over this poor drug that does more damage than good ."

1 / 10

Was this helpful?Yes No

2 Report

Dixie
November 8, 2022

"I had the injection done after my pinkie and ring finger became significantly contracted. I was assured that my research saying it could be a quite painful procedure was wrong. In fact it was incredibly painful and I had swelling and severe bruising in my entire hand and arm clear up to my underarm and lymph nodes; the doctors response was that I had had an abnormal reaction. The waiting period between the injection and manipulation kept me awake with nerve pain. My fingers straightened, but in the five months since the procedure I have weakness, aches and pain in the arm where it bruised. While it appears I need the procedure in the future in my (dominant) right hand I am extremely hesitant to even consider it and will likely evaluate other options."

3 / 10

Was this helpful?Yes No

1 Report

Are you taking this medicine?

Anonymous
Taken for less than 1 month
August 12, 2022

"Very painful and creepy. Hand mangled bruised, skin ripped open. Took time off work, wore a splint at night. A year after it came back with a vengeance. Twice the scar tissue, fingers crooked up even more."

1 / 10

Was this helpful?Yes No

1 Report

Games
Taken for less than 1 month
October 2, 2022

"I had the xiaflex injections on my right hand and was amazed how easy and non invasive the process was. The next day my Dr gave me a local injection pain killer and manipulated my fingers. The result was instant with no ill effect’s. I would recommend this procedure over surgery. I understand that xiaflex is no longer available in Canada and think this is unfortunate for others suffering from this problem."

10 / 10

Was this helpful?Yes No

1 Report

Barry
Taken for 2 to 5 years
June 3, 2022

"I've had 2 injections into each hand to correct my Dupuytren's contracture in my pinkies and it didn't work. Each time the pinky went back to the way it was prior to the injection. I have recently had surgery on my right hand to remove an excess amount of scar tissue, the likes my new doctor had never seen before. Did more damage than good."

1 / 10

Was this helpful?Yes No

1 Report

Tomb
Taken for less than 1 month
May 9, 2022

"Horrible experience with Xiaflex. Worst medical decision in my life. Allowed hand surgeon to talk me into treatment with Xiaflex. After treatment my contracture eventually grew massive, then surgery leaving horrible scar tissue. Today had surgery to remove scar and graft."

1 / 10

Was this helpful?Yes No

1 Report

Diamo...
Taken for 1 to 6 months
July 14, 2021

"Had left hand done in May and now having right hand manipulated tomorrow. Xiaflex injections are somewhat painful but worth it. The local injections are worse but tolerable, manipulation is nothing. Had minor bruising but no problems otherwise. My right hand has swollen and been a little more painful since Xiaflex injection earlier but I am right handed and use it more. Find a good doctor and get this done, nothing to it!!!"

10 / 10

Was this helpful?Yes No

1 Report

Alex
Taken for less than 1 month
September 6, 2022

"I had it done 5 years ago (the first finger hurt like hell, the second finger I demanded a local). So now one finger is fine and the other is about 20 degrees but ok. So now I have 3 more fingers that are problematic and I go in tomorrow with apprehension due to the pain...local will be demanded. Also, after the first finger was done I had pain for a couple of weeks. The second finger was fine???"

8 / 10

Was this helpful?Yes No

0 Report

MFK
October 9, 2022

"I was treated for Dupuytren contraction for the ring and pinky finger on my left hand. I had significant discomfort with the Xiaflex injection on fingers, subsequent swelling of the left hand and minor discomfort in the left armpit, which also turned red. However, after two weeks the improvement to the fingers has been almost 100% and it appears to be continuing to improve. Hopefully, I never have to have it again. However, if necessary, I would. Be advised, I’m a 69 year old male in good health."

10 / 10

Was this helpful?Yes No

0 Report

firec...
Taken for less than 1 month
June 10, 2022

"It hurts like anything but is well worth it. Pain is only while you are receiving the injections. Almost normal after 3 days. I think finding a doctor that does this a lot is key and catching it early. My shots were paid for by a grant except for $150. which the company selling the drug took care of."

Was this helpful?Yes No

0 Report

Amelia...
Taken for 2 to 5 years
July 28, 2016

"A very positive experience without noside effects."

10 / 10

Was this helpful?Yes No

11 Report

Unhappy...
October 9, 2021

"Had injection. Painful. But no side effects. In fact, no effects at all. Xiaflex did not work for me. Went on the have surgery which resulted in 80% improvement."

1 / 10

Was this helpful?Yes No

4 Report

Anonymous
Taken for less than 1 month
May 28, 2023

"Had this procedure done 2 weeks ago and… it’s coming back. Waste of time and money. Extremely painful and stressful."

1 / 10

Was this helpful?Yes No

1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.