Chlorpheniramine / hydrocodone for Cough User Reviews
Brand names: Tussionex Pennkinetic, TussiCaps, Hydrocodone GF, HyTan
Chlorpheniramine / hydrocodone has an average rating of 9.4 out of 10 from a total of 103 reviews for the treatment of Cough. 95% of reviewers reported a positive experience, while 3% reported a negative experience.
Reviews for Chlorpheniramine / hydrocodone
- Suz...
- June 23, 2013
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I am a 38-year-old female who has lupus, asthma, and chronic bronchitis. After 2 months of violent coughing fits at night, I was prescribed Tussionex Pennkinetic. The coughing ceased immediately, as did the pain, and I could finally breathe! It did cause itching, strong drowsiness (a plus because I was sleep deprived), and dry mouth, but it was absolutely worth it."
- Nik...
- June 26, 2017
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Best cough syrup in the world for bronchitis and asthma. I measured and took it as prescribed for 7 days once a day and didn't get high or addicted. Works better than that trash promethazine cough syrup. The government has cracked down so hard on doctors they're scared to help you with what you really need. This cough mixture deserves a 10 or more, like a 100! I stopped coughing in 5 minutes and felt better, period. No tight chest, although on antibiotics. This is what I'd recommend to any suffering like me."
- sop...
- Taken for less than 1 month
- September 23, 2016
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Probably the BEST cough suppressant you can ever be prescribed. I had a cough that was SO SEVERE it kept me up 2 days straight and my throat began to bleed. My doctor prescribed 1 tsp every 12 hours and a Z-pack antibiotic. I took the dosage at 6 PM and by 7 I was sleeping soundly. I used it to ward off the cough while the antibiotics cured the cough. No point in getting just cough medicine if you don't get the antibiotics to go with it :)"
- Gra...
- May 17, 2016
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Works very well for cough suppression. Much more effective than guaifenesin with codeine. One adult dose at bedtime, and I can sleep through the night, 8 hours, and wake up with very minor 'hangover' that quickly wears off. Used for deep bronchitis cough, atelectasis after pneumonia, severe flu infection."
Are you taking this medicine?
Your review helps others make informed decisions.- TBa...
- Taken for less than 1 month
- February 28, 2016
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is hands down the best cough medicine I've ever taken. I had a cough so severe that I wet myself or threw up during uncontrollable coughing fits. Needless to say, I couldn't sleep at night for more than the few hours when I just passed out from total exhaustion. My first dose of Tussionex didn't totally get rid of the cough, but it did cut it by about 50%. The second dose helped more. My third dose was last night, and it made it possible for me to get a good night's sleep for the first time in two weeks. I did wake up once with a bad headache, but I can't tell if it's a side effect of the medicine or just part of being sick. Anyway, I'll trade a headache for vomiting from coughing fits any day."
- grc...
- February 13, 2017
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "A doctor once described this medicine to me as the 'cough syrup of champions.' He wasn't joking. My cough is gone within 10 minutes of drinking this golden liquid miracle. The only reason I didn't give it a full 10 is because of the risk of addiction. It feels amazing-so amazing that you might be tempted to take a little more. Just be careful and take it EXACTLY as prescribed."
- MDN...
- November 23, 2015
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is the ONLY cough medicine that works for the bronchitis/asthma nighttime cough I have, unfortunately, for about 20 years. I just discovered this about 7 years ago, maybe. To me, I have other family members who get this awful cough that OTC meds and other RX cough meds don't even come close to touching...one dose of this does the trick. We dubbed it 'liquid gold,' not to mention most insurances won't cover it, and at anywhere from $80 to $125 a bottle (big OUCH!). I have bought it in desperation for sleep and feeling better. PLEASE sell the antihistamine part separately! I don't care about the narc part."
- Gru...
- Taken for less than 1 month
- July 7, 2012
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I was having coughing episodes about 3 hours long. I coughed until I vomited and even until I lost control of my other bodily functions (both of them). I basically did not sleep more than 3 hours a night (if that) for a week and a half. Since I can expect this cough for another 4 weeks to 4 months, I broke down and gave this a try. It is a testament to the sheer physical force of the pertussis cough that Tussionex only stops it by about 80%. But that 80% makes all the difference! I am sleeping adequately and can keep food down. The unpleasantness that goes along with taking opiates is far, far preferable to this vicious pertussis cough."
- Mic...
- January 30, 2014
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This cough syrup really works great on quieting my wicked cough (bronchitis)... however, I am one of the few who has a terrible time sleeping when I take it. It also makes me woozy - the equivalent of drinking two glasses of wine. That said, I try to take it at least 6-8 hours before bedtime. The good effects (cough suppressant) are still working, and I get a good night's sleep. I cannot drive while taking it. Stay safe!"
- Tee...
- Taken for less than 1 month
- May 9, 2016
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is by far and wide the best treatment for coughing. The worse your cough is, the fewer 'high' feelings you will have. I don't mind the hazy feeling all opioids tend to give off, so this is an added benefit for me. The meds help relax your entire body. It can be difficult to sleep on it."
- Wat...
- Taken for less than 1 month
- November 17, 2015
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is my go-to cough medicine, it absolutely works the best for bronchitis cough or sinus infection. I have experienced headaches with this but found that if I drink a lot of water when I take it, that helps. We call it super syrup in our house."
- Tig...
- April 17, 2016
"My colds always turn into bronchitis. This time it turned into pneumonia. This medicine is liquid gold. Don't let any doctor tell you otherwise. Some doctors like to prescribe Tussionex Pearls for chronic cough. Don't let them. This is the cough syrup of all cough syrups. After I was released from the hospital, I took my first dose and 30 mins later, no cough!!"
- jla...
- August 26, 2013
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This medication will take a cough away, but I didn't like the side effects. I normally react great to pain meds, but not on this. Couldn't sleep the first night. Woke up with a severe headache. Had to take another dose for this cough and still bad headache. Can see this will turn to a migraine. Was so hopeful of this medication."
- bar...
- November 2, 2009
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I have been to several internists, three pulmonary docs, and still have a chronic cough. Other than perhaps an asthmatic condition, so far no specific diagnosis. Nobody could stop the cough. I tried virtually everything until I came to my latest internist, who said he could stop the cough, and he did. He prescribed Tussionex Pennkinetic. Unlike most of the other comments, I don't feel loopy, I feel normal as can be, except I can't sleep. So, with a bit of an Ambien, I sleep, I don't cough much anymore, and feel great. I take two teaspoons daily each and every day, or I am in trouble. I have done this now for about three years, and the end results have kept me off Prednisone and able to live a normal, healthy, active life. Hooray for this medicine!"
- Coo...
- January 13, 2012
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I have taken Tussionex for a few years. Before that, I was on inhalers, etc., for my allergies and cough. New doctor finally prescribed Tussionex for me. I realize it can be addictive if not used right to the letter. My doctor was reluctant to keep refilling my prescription until I would come in and show him how serious my sinus drainage and cough were. I am so thankful for this medicine. I am 70 years old, still working and taking care of a 10-year-old grandson. Without this medicine, I can be just sitting and the clear liquid would drain from my nose. It does not make me drowsy or sleepy at all. Love this medicine and make sure I never abuse my dosage."
- Tac...
- August 21, 2018
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "I have had a chronic cough since I was a freshman in high school (I'm now 24). I have been to every specialist, tried many, many treatments, and nobody can figure out what is wrong with me. I've even been to Jacksonville's Mayo Clinic specialty cough clinic, where they ran extensive tests over a 3-day period; took biopsies of my lungs, esophagus, and trachea, had a CT scan of my chest, did a pH probe test, checked for asthma (much more extensive test than the traditional method of detecting asthma), and much more. Nobody can figure out what is wrong with me. I'm at the point where the next treatment option will be Botox injections into my neck to paralyze the nerves in hopes that it helps with the cough reflex. Now, you might be asking yourself, is the above relevant? The answer is yes, and here's why. After reading my extensive summed-up cough history, and concluding that nobody has any idea what is wrong with me, the only short-term relief I am able to get is from Tussionex."
- Luk...
- Taken for 10 years or more
- August 18, 2019
"Had chronic cough for 15 years. Had 5 MDs and an ENT specialist work me up, but no reason found. Cough so bad head spins, try to not pass out. Once last winter fell on the wood stove due to a bad cough attack [it just comes on in a second]. Have been on TUSSINEX for years, two or three 115 ml bottles a year, and it REALLY WORKS GREAT. Doctors know it works well, but the opioid abuse makes doctors leery. Fortunately, I have a doctor that will prescribe when I need a refill [must have paper script]. You should not have to PLEAD with your doctor for a better quality of life. Good luck, all."
- Bay...
- Taken for less than 1 month
- May 20, 2013
TussiCaps (chlorpheniramine / hydrocodone) "I have had severe hay fever allergies for the past 14 years of my life. This spring was like every other, I had my regular allergy injection (steroid), and it still didn't kick the symptoms. I was diagnosed with bronchitis about 3 weeks into allergy season and prescribed a 10-day dose of this medicine for my cough. Not only did it cure my cough immediately, all of my allergy symptoms have disappeared while taking this. I have never breathed so well in the springtime!"
- Wai...
- October 16, 2013
"Every fall/winter I get a minor cold that goes away quickly, but the horrible cough lingers and turns into bronchitis. Every fall/winter I beg the doctor for another bottle of this stuff. After trying a dozen other medications, this is the only one that works all the time. It is fabulous."
- ano...
- Taken for less than 1 month
- January 3, 2013
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This is the nastiest looking and tasting medicine I have ever taken. With that said, the medicine works the best for a cough. I kept myself and my husband awake at night coughing. I took this medicine (only at night), and it worked like a charm. This is the best medicine for a cough (I don't waste my money on Robitussin or Mucinex) and is my go-to medicine whenever I get a pesky cough."
- Sha...
- Taken for less than 1 month
- July 21, 2020
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Went to ER with breathing issues, tested negative for COVID, X-rays, blood work, and ECG came back normal, but couldn't take a deep breath, and when I did, I hurt. Doctor prescribed this liquid gold, 10 minutes after taking it, my cough was gone and I could breathe."
- Anonymous
- January 25, 2011
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "Whenever I get a cold, I get a wicked cough that actually makes me throw up, it is so bad. I took every cough syrup known to man, and nothing worked until my dad, who is a doctor, tried Tussionex. It was incredible, I was better in 48 hours! I only get a cold like this every few years, but this medicine is the only one that works, and doctors are afraid of it because it is a narcotic. But if nothing else works, why make people suffer?"
- Anonymous
- January 15, 2009
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This stuff is a miracle cure for nasty coughs. I was prescribed this for a painful, dry cough that was unresponsive to codeine and OTC cough medicines. It completely killed my cough and allowed me to relax and sleep. If I were a doctor, I'd give this stuff out instead of codeine."
- red...
- December 22, 2009
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "First of all, if you go to a doctor and request this medicine, he/she will see this as drug-seeking behavior. It is an opiate. The only difference between Tussionex and Vicodin is the antihistamine in the Tussionex. It is highly addictive. I should know... I have been to drug treatment two times for my addiction to Tussionex. I didn't take it as prescribed, though - worked my way up to 3 oz. each day - sometimes twice a day. Be very careful."
Learn more about Cough
Care guides
Medicine.com guides (external)
More about chlorpheniramine / hydrocodone
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (131)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
- En español
Patient resources
- Chlorpheniramine and hydrocodone drug information
- Hydrocodone and chlorpheniramine (Advanced Reading)
- Hydrocodone and chlorpheniramine polistirex (Advanced Reading)
Other brands
Tussionex Pennkinetic, TussiCaps, Vituz
Professional resources
- Hydrocodone Polistirex and Chlorpheniramine Polistirex Suspension prescribing information
- Hydrocodone and Chlorpheniramine (FDA)
- Hydrocodone and Chlorpheniramine Solution (FDA)
Tussionex Pennkinetic (chlorpheniramine / hydrocodone) "This Tussionex Pennkinetic is hands down the best cough medication available. Over the years, I've tried many prescription and OTC cough medications, and I've had bad side effects or felt no relief from them. When an ER doctor prescribed me Tussionex, I realized I've found the only medication that does not give me side effects and actually works! This syrup clears up my cough and helps decrease my post-nasal drip and congestion. I am now presumptive positive for COVID, and my PCP gave me a fill of Tussionex to help with the cough associated with the illness, and it still works great!"