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Omnicef User Reviews & Ratings

Omnicef has an average rating of 5.6 out of 10 from a total of 51 reviews on Drugs.com. 39% of reviewers reported a positive experience, while 35% reported a negative experience.

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Reviews for Omnicef

Commonly mentioned side effects
  • aub...
  • March 29, 2020

"This drug cefdinir makes me feel like I am dying. I was prescribed Omnicef for a severe UTI that traveled to my kidneys. By day two, I am vomiting profusely, I cannot stop having diarrhea, and I genuinely feel like I am hallucinating and dying. I want to stop taking this medicine, but I cannot deal with the pain of UTIs. I’m lost. Please say no to this medication and stay away at all costs."

2 / 10
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71 Report
  • tig...
  • November 2, 2013

For Sinusitis "Fantastic at clearing the sinus infection. I'm on day 4 and it's almost completely gone. The first two days were miraculous. But then, starting day 3... My stomach and intestines are rumbling almost constantly and I'm 'pooping' brown water 5+ times a day. I'm also utterly exhausted and weak, making it virtually impossible to actually do anything. If this gets much worse, I'm going to have to stop using this before the 10-day course runs out."

4 / 10
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81 Report
  • Anonymous
  • December 12, 2011

For Strep Throat "Omnicef worked, but it took until the 5th day on it to finally feel a tiny bit better. I had some side effects, and my throat hurt so bad I couldn't sleep for three nights. I saw no visual difference until the 9th day. It almost looked as if on my third day it had gotten worse."

5 / 10
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71 Report

Frequently asked questions

  • Ran...
  • August 20, 2018

For Sinusitis "I started taking this for a sinus infection. The first 5 days I was fine and just added extra yogurt to my diet to be safe. By day 6, I had a little bit of diarrhea, which was expected. It turned into diarrhea every 45 minutes until I had nothing left for the next 24 hours. Then it was like my bowels were being turned inside out, and all that came out was black mucus. I immediately stopped the medication. I’ve been about 36 hours without it, and things are slowly looking up. But I have had to miss work and other events because of it. My doctor said this was safe for those that are allergic to amoxicillin, but apparently not. I do not recommend this to anyone. If you read most other reviews, it’s about the same thing."

1 / 10
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39 Report
  • Emm...
  • August 5, 2010

For Sinusitis "I have taken it many, many times for my chronic sinus infections, and it seems to be the only thing that ever gets rid of the infection. I do get stomach aches from it and nausea, but it does what it's supposed to."

7 / 10
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54 Report

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  • Ano...
  • Taken for less than 1 month
  • July 30, 2022

For Middle Ear Infections "The worst side effects ever! Started taking for inner ear. First day wasn't so bad, but the second day! I was in full panic, ringing in the ears, mouth sores, tingling pins and needles up and down my face, rise in my BP and last but not least my face would go hot! Usually during a panic attack, I could calm myself down. Not this time. I couldn't figure out what was going on, couldn't have imagined an antibiotic would do this. Most of my symptoms have disappeared after one day of not taking except for the tinnitus. Hopefully it will calm down soon."

1 / 10
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12 Report
  • Anonymous
  • March 25, 2011

For Sinusitis "300 mg 2 x day for 7 days prescribed for sinusitis. I think I may have felt like I was getting slightly better the 2nd and 3rd day, but after that it went back to the same as before. No adverse side effects, just didn't seem to work."

2 / 10
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35 Report
  • Sta...
  • February 7, 2012

For Bronchitis "Within 36 hrs, symptoms started to subside. Had no side effects with stomach (take with food). I suffer from bronchitis about twice a year. This medication was much more effective than Z-packs, Amoxicillin, or Cipro. I started getting mild headaches around day 4. Felt better but didn't clear up cough and wheezing."

6 / 10
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34 Report
  • jhh...
  • April 10, 2009

For Sinusitis "Omnicef was effective in treating my daughter's sinusitis. However, she broke out in hives a day after finishing the medication. Although it is not certain the medicine caused her hives, it is very ironic that they broke out within 24 hours of finishing the antibiotic."

8 / 10
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34 Report
  • Anonymous
  • November 9, 2011

For Middle Ear Infections "This is my first time taking this medicine. I was diagnosed with bronchitis and an ear infection. I was told to take probiotics to prevent any diarrhea. I have not had any side effects. I'm feeling much better."

8 / 10
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27 Report
  • Jen...
  • January 1, 2010

For Middle Ear Infections "My son had an ear infection, and the doctor always gives amoxicillin first, and it never works. He always has to get Omnicef, and then he starts getting better. He does have light diarrhea occasionally, but nothing too horrible. I've had an ear infection myself, and I was sick for 2 weeks before I went to the doctor. Thought I had a bad cold, but when it just wouldn't go away, I found I had fluid buildup in my ear. They prescribed Omnicef, and it worked. I didn't have any diarrhea even though I already have severe IBS! I'd definitely recommend it."

10 / 10
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28 Report
  • Anonymous
  • November 6, 2010

For Middle Ear Infections "My daughter, who was 14 months at the time, had a severe reaction to this medication after being prescribed for a 3rd ear infection in a year. She actually got worse and had severe side effects (aside from the gastrointestinal as mentioned by others), including vomiting, continued high fever, and by the end of the second day - hives. I list it as a drug allergy now on all her medical paperwork."

2 / 10
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29 Report
  • Shu...
  • January 21, 2016

For Bronchitis "Worst experience ever. I took one capsule and two hours later, I started diarrhea. I only took one more tablet 12 hours later. I had diarrhea for 4 weeks. I had a hemorrhoid flare-up. Never again will I take this drug. I think it took about 4 months to get my gut straightened out. Be very cautious of this drug."

1 / 10
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15 Report
  • Anonymous
  • February 16, 2017

For Sinusitis "I took this medicine for ten days. I took 300 mg twice a day. It was horrible, the side effects that I experienced. I had the worst yeast infection and broke out in the worst rash I have ever seen. It would bleed and itched so bad it about drove me crazy. I finally went back to the doctor. It took three months to get it all healed up. They should take this medicine off the market."

1 / 10
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18 Report
  • Off...
  • November 20, 2015

For Bronchitis "I was prescribed 300 mg Omnicef. 1 capsule 2x a day. Very bad experience. I have had extreme diarrhea since the third day of taking this med. It is now 2 weeks after I finished the dose and am still experiencing problems. This med kills every 'good' bacteria in your gut. I've been taking several different kinds of probiotics trying to get myself back to normal. This has been and still is an awful experience. Do not take this unless you like running to the bathroom every 30 minutes for weeks on end. I have not been able to eat much of anything and am still losing too much weight. It is a very dangerous drug. I will NEVER take this again."

1 / 10
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12 Report
  • Anonymous
  • June 21, 2010

For Middle Ear Infections "This is the only antibiotic I will request for both of my children when they have ear infections. It is a one dose-a-day medicine that begins working very quickly and clears the infection. Diarrhea is a side effect, but can be controlled with diet and limiting dairy."

10 / 10
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19 Report
  • Anonymous
  • April 13, 2009

For Middle Ear Infections "My son, who just turned one year old, was prescribed this medication after two medications prior did not work to cure his ear infection. I was skeptical of using this medication at first, but after the desired result was achieved, I certainly do not regret it."

10 / 10
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13 Report
  • Boo...
  • April 25, 2016

For Sinusitis "I have been on this for 5 days, sort of working, still have the headache though. I haven't really had any side effects yet. But I was given a 21-day dosage for (2) 300 mg capsules. I have had 4 sinus infections since January. Hope it helps get rid of the headache. It has helped with the drainage and coughing though."

4 / 10
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9 Report
  • Fra...
  • Taken for less than 1 month
  • February 13, 2018

For Pneumonia "My sister’s pediatrician gave her this antibiotic to treat her flu. My sister is 15 years old but has a rare syndrome, and she is still like a baby! She got very bad stomach pain, black stool, and the worst part! We almost lost her by a seizure! She hasn't had a seizure in 10 years! Horrible experience! Never recommending this!"

1 / 10
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7 Report
  • Str...
  • Taken for less than 1 month
  • October 28, 2015

For Strep Throat "I was diagnosed with strep, nasal infection, and an ear infection about 5 days ago. I took cefdinir as directed for 5 days and saw little to no results. Some side effects for me that were not listed were my stool smelling of the dissolved pill and also my urine."

4 / 10
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7 Report
  • Anonymous
  • January 29, 2010

For Middle Ear Infections "I was prescribed Omnicef for a sinus infection that caused fluid to collect behind my inner ear. It worked great for the first 6 days. Somewhere around the 7th day, I developed terrible vaginal itching. Worse than anything I have ever experienced before. As soon as I stopped taking it, the itching went away within 2 days."

6 / 10
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12 Report
  • Anonymous
  • November 7, 2011

For Middle Ear Infections "My son has taken this before, and it worked fine. My 17-month-old daughter was just prescribed this after amoxicillin didn't take care of her ear infection. After 4 days, her gums swelled up really bad, became bright red, and then started bleeding on the 5th day. She also developed diarrhea. I immediately took her back, and they put her on Zithromax. I think we are finally on something that will work for her. My son can take this medication, but my daughter can't."

5 / 10
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16 Report
  • fut...
  • February 13, 2010

For Middle Ear Infections "My daughter is 11 months and has taken Omnicef for 4 days now. Using it for bilateral ear infection. She has spit up a few times but is feeling a whole lot better. No other side effects. Hopefully, she will keep getting better. Only time will tell. Definitely would recommend this antibiotic."

10 / 10
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12 Report
  • 191...
  • June 15, 2016

For Pneumonia "Let's talk about my sickness first. I was dipping myself into a freezing water pool for approximately 5 minutes a day. The next morning, I felt the weather was so much colder, so I knew it was a fever. I'm a very healthy person, I make sure that my body is clean. I drink a lot of water and cleaning drinks, so my stomach is always clean. The doctor prescribed me Fevadol and Omnicef. The Omnicef experience was horrible. Very bad diarrhea every 15 minutes or so, even if there was nothing in my body. I couldn't sleep for more than 24 hours with complete alertness and no feeling of exhaustion. Eating it without food will make it worse. I used it for 2 days only. The dosage was 300 mg twice a day. I got dizziness, back pain, headache, and diarrhea."

1 / 10
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13 Report
  • Man...
  • June 13, 2015

For Middle Ear Infections "My daughter has had over 6 ear infections, only being 22 months old. She took amoxicillin for all of them, but it just didn't work. The doctor gave her cefdinir (however it's spelled), and I'm pretty sure it hasn't worked. It gives her red diarrhea, and horrible diaper rash, and she itches that area quite a bit. She's getting tubes put in next week, so hopefully that ends this horror!"

6 / 10
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10 Report

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