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Epidiolex User Reviews & Ratings

Epidiolex has an average rating of 5.3 out of 10 from a total of 4 reviews on Drugs.com. 25% of reviewers reported a positive experience, while 50% reported a negative experience.

Condition Avg. Rating Reviews Compare
Lennox-Gastaut Syndrome
3.7
 3 reviews for Lennox-Gastaut Syndrome 18 medications

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  • K I...
  • Taken for 1 to 6 months
  • May 1, 2022

For Lennox-Gastaut Syndrome "My daughter began using this medication in conjunction with the ketogenic diet and Lamictal. It seemed to help at first with startle seizures, but then other small daily seizures began occurring, and the startles have come back somewhat milder. I was very happy to try CBD covered by insurance, but I’m very unhappy that this medication contains sucralose. I am trying to improve my daughter’s gut health, which has a strong link to all her health conditions, and sucralose is terrible for gut health. They need to make this med with clean ingredients. No wonder a main side effect is diarrhea."

3 / 10
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  • Ano...
  • Taken for 6 months to 1 year
  • April 14, 2025

"My daughter, who is 30, has had intractable epilepsy with daily drop seizures since she was 6 years old from encephalitis. She is on many seizure medicines. Epidiolex 2.25 mg twice a day was added, and for the first time ever, she has gone several months without seizures. Side effects are anger, sleep problems, and tiredness. We are trying to slowly adjust the Epidiolex down somewhat to see if the side effects can be minimized."

10 / 10
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0 Report
  • Gal...
  • Taken for less than 1 month
  • August 8, 2023

For Lennox-Gastaut Syndrome "My son, 9, has recently started on 60mg BD and keeps dropping off to sleep throughout the day. This has not happened before. Seizures are slightly better. It's still early days, so it's hard to tell if this medication will be a game changer."

7 / 10
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2 Report

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  • Anonymous
  • Taken for 6 months to 1 year
  • May 16, 2023

For Lennox-Gastaut Syndrome "My daughter lost her appetite, and her behavior changed completely. She was irritated all the time and unbearable with everything around her."

1 / 10
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3 Report

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