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Wellbutrin SR for Depression User Reviews (Page 3)

Reviews for Wellbutrin SR

Commonly mentioned side effects
  • byn...
  • January 16, 2018

"Took me 2 tries to get on it. The first time I tried it, it sent me into an anxiety attack for 3 days, and I had to stop. I think this was my own nerves, though. Waited a couple of months, then tried again. This time it went much better. The first 4 days had a lot of head fogginess and jitters, but otherwise not too bad. After that, suddenly I felt much better! My mood improved a bit, I had much more energy (I wasn't getting that mid-day crash anymore), and I was getting fewer headaches. But the cons of it were constipation, mild moodiness, and anxiety in the evening and towards going to sleep for some reason. Not a terrible experience, but ended up being a bit too much for me to handle as a full-time student."

8 / 10
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  • Fem...
  • Taken for 10 years or more
  • December 24, 2016

"I credit Wellbutrin for my life. Started taking 150 mg Wellbutrin SR 15 years ago to combat the sleepy side effect of Prozac (taken for depression). About a year later, I dropped the Prozac (because of sexual side effects). The Wellbutrin is enough to keep me normal. Over the 14 years, I have tried 1: The no-name brand (almost a disaster - made me sleepy & more depressed - fortunately, I figured it out before getting suicidal) 2: The name brand long-acting version - again made me sleepy and more depressed. 3: Took 2 by accident once or twice - okay until it wears off, then withdrawal feeling/depressed. 4: Sometimes I take one in the afternoon (when I am unemployed and more depressed), this works pretty well provided I take it before 3 pm - or it keeps me awake."

10 / 10
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  • Tor...
  • October 11, 2016

"I started taking this medication last week. I started suffering from depression when my marriage began to fall apart! I was trying for years to be there for my husband as he returned from a deployment suffering from severe PTSD! Right now I can say my opinion on this medication differs. One day I'm fine and can get through my day calm, other days I have severe anxiety and I'm freaking out, or I'm so tired with headaches that I just want to be alone and sleep all day! A big concern, even though I shouldn't be complaining about, is losing weight. In a week I have already dropped 5 pounds! I feel as if I should give this more time to balance me out! I'm only on 150 mg once a day."

3 / 10
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Frequently asked questions

  • Ste...
  • July 31, 2015

"Was having some anxiety and depression issues due to many life factors. Was told that Wellbutrin would be a good option and that it was fairly mild. The first few days had the euphoric feeling everyone talks about, but this ended in 2-3 days. After that, anger kicked in to the point where I was taking walks at 1 a.m. to calm down and relax. From there, the weirdness kicked in. A feeling that's hard to describe, but life got very flat. Didn't feel anything, just flat. I felt like I had a lobotomy or something. At a party last week, a friend asked if I was stoned as I looked out of it. Then I forgot to take it one day, and I felt great that day-joy, emotions, had fun. I then took it the next day and felt horrible. Cold turkey and happy, not for me."

3 / 10
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  • Ano...
  • Taken for less than 1 month
  • September 22, 2012

"This has been prescribed by my doctor as an add-on antidepressant to Lexapro, which I am taking, as Lexapro did not seem to be working just by itself. I think this medication is pretty good. Overall, I feel much less depressed since taking it and almost feel back to my old self. The only side effect I get with this medication is sweating. I would definitely recommend this medicine to other people."

6 / 10
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  • Mau...
  • Taken for 2 to 5 years
  • December 4, 2017

"I have been on 150 mg of Wellbutrin SR for a little over 2 years. If I could go back and do it over again, I never would have started taking it in the first place. It wasn't until I was taking the medication for about 4 months that I really started noticing hair loss. It slowly started to get worse. On top of that, I noticed ringing in my ears. The first few months were great, I had more energy, I lost weight, and I felt great. I have been trying to wean myself off of Wellbutrin, however, it's been extremely difficult because of the horrible withdrawal symptoms. Even tapering off a little has been extremely difficult. I wish I would have done more research on the side effects and possible withdrawal symptoms."

3 / 10
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  • Anonymous
  • November 29, 2008

"I tried various other anti-depressants. I have severe depression, which runs in my family. Wellbutrin works well for me. The only noticeable side effects have been twitching and some sleeplessness. It is expensive, though. The generic was just terrible. Gave aching, even more twitching, tiredness, lack of concentration, etc. I would not recommend the generic, as many other people had similar complaints. I do recommend Wellbutrin SR NON-GENERIC, especially if you have insurance."

10 / 10
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More FAQ

  • Cas...
  • Taken for 1 to 6 months
  • July 18, 2019

"I took 100 mg for one month, and it really helped with hormonal migraines that I suffer from daily. Cramps and body aches were gone. Worry about the PMDD gone. Depression - gone. I had a lot more energy! I really was so happy until I realized that my face hurt with raw deep acne lesions. My forehead was completely covered (never happened before in my life) as was the rest of my face (usually only on chin and jaw areas at PMS time). I did experience bad ringing in my ears for the first 3 weeks, and it was tougher getting to sleep. I could handle all that, but not the pizza face. Too bad :( I also experienced hair thinning, but that could be from PMDD. I'm not waiting it out and letting my skin continue to scar."

7 / 10
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  • D-0...
  • Taken for less than 1 month
  • May 1, 2015

"I've been on the generic version of Wellbutrin SR 100 mg once a day a little over a week. Added to supplement my 20 mg Prozac twice a day and 0.5 Klonopin twice a day. I've been on the Prozac and Klonopin for over a year, and it began to be not as effective. I began to feel very depressed along with my anxiety, also, I've gained about 20 lbs, so my psychiatrist prescribed 100 mg Wellbutrin SR once a day in the morning to help. So far, I've noticed I'm extremely tired about 1 hour after taking it, so tired even my strongest cup of coffee can't keep me awake. I know Prozac and Klonopin can have this as a side effect, but my body is well adjusted to that now, those side effects are long gone. I've noticed better focus and reduced appetite, so now I will just wait."

7 / 10
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  • epi...
  • Taken for less than 1 month
  • May 10, 2016

"I took Wellbutrin 150 mg once a day, alongside Zoloft (200 mg) and Atenolol (50 mg). The Wellbutrin worked well for the first four days, but then I suddenly began to plummet. Instead of feeling energized like everyone else in these reviews, I began to feel restless, drowsy, and dizzy. Even worse, I noticed my blood pressure was going up. By the third week of taking this medication, my head was pulsing, I had a couple of bad headaches, diarrhea, and nausea. I could not take the side effects anymore because I was experiencing almost every negative side effect. If you are sensitive to caffeine, this drug may not be for you. It felt similar to caffeine, which I am sensitive to."

5 / 10
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  • C M...
  • Taken for 2 to 5 years
  • July 12, 2023

"I have major depression, generalized anxiety disorder, PTSD, PSSD (Post-SSRI Sexual Dysfunction), and ADHD (combined type). Wellbutrin worked wonders for me in the first year as far as depression. It did not seem to have any (negative or positive) effects for me for ADHD, anxiety, or any sexual effects. I kept needing an increased dose for the same effect and maxed out the dose a year ago and it no longer helps me at all. That one year of happiness was worth it though as I had no side effects while all SSRIs and SNRIs have tons of side effects for me."

7 / 10
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  • Anonymous
  • Taken for less than 1 month
  • January 30, 2014

"I felt it working in a couple of days, and I felt great! The depression lifted, and I felt so much more energy, no more crying, and actually wanted to do things! There is depression that runs in my family, and I also feel like it happens more seasonally in the winter. However, after a week of taking it, I developed an allergic reaction and broke out in hives on my legs. This is the first allergy I've ever had! Had to stop taking it due to the reaction, and now I've been put on Pristiq... we will see how things go."

3 / 10
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  • Sly...
  • September 5, 2010

"I'm on my 5th day of starting Wellbutrin SR (generic) 100mg and feel more energetic and less depressed and lethargic. That could be a placebo effect so early in treatment, but I know for sure that it's almost completely taken away my appetite. I actually forget to eat. I had been on Prozac, which worked great at first, and then the therapeutic effects seemed to fade over the months until I was severely depressed again. This has happened to me with several other antidepressants as well. I hope that Wellbutrin will work consistently for me. So far, I'm very happy with the results."

7 / 10
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  • lov...
  • November 28, 2011

"I was prescribed generic for Wellbutrin 10 days ago. I felt great the first couple of days, but the last couple of days I feel really depressed, constantly crying and yelling at my husband and kids for no reason. Just left a message for my doctor to call me back to see if we can change either the dosage or the medication period."

5 / 10
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  • 17...
  • December 19, 2010

"I have been on this medication for less than a month already, and to be honest, I still haven't noticed anything too big yet. I have severe depression and have tried four other medications, and all they did was make me tired and antisocial. With this, I don't fall asleep during class or eat a lot, but I still feel like I'm not completely here. I feel sad, and I have been crying a lot over small things, but I'm still giving it time, and I feel confident about this."

7 / 10
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  • Anonymous
  • October 16, 2011

"I was finally prescribed Wellbutrin SR after four months of treatment with a hospital psychologist. Treatment through other means of talking through my emotions helped some, but there were those thoughts, if you know what I mean. So they started me on the medicine. It was only 100 mg one time a day, I only took it for ten days. I felt great for about ten hours, but in the evening I would feel like I was in withdrawal or like I was in an emotional craving of some sort, kind of hard to describe. I felt edgy at night, was easy to bark at the kids for little or no reason, and I would have deep and serious thoughts about suicide, but those thoughts only lasted about ten minutes, and then they would go away, as quickly as they had started."

9 / 10
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  • 89U...
  • November 24, 2009

"I have been prescribed many medications, and I must say that Wellbutrin has been my lifesaver. I can honestly say that not all medicines are right for everyone. If you feel that your current medicines are not helping, please talk to your doctor."

9 / 10
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  • LAJ...
  • June 2, 2011

"I've only taken Wellbutrin SR for a couple of days, and I've had a light headache, but I've been able to focus and concentrate, and I'm so happy that I've been productive too! If headache is the only thing I have to deal with, I'll keep taking it."

6 / 10
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  • mjw...
  • December 18, 2011

"This medication is great. I've tried several other antidepressants, and this one is by far the most effective, especially when taken concurrently with an SSRI. The only bad thing about it is it makes you shake like a leaf. I once spilled a drink all over me because I couldn't hold it steady. But this side effect is insignificant in comparison to the benefits of taking the medicine."

9 / 10
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  • gig...
  • Taken for 1 to 6 months
  • May 14, 2015

"I've been on Wellbutrin 150 mg 2x daily for a month now, and the only thing that I've noticed is I'm extremely exhausted about an hour after I take it. It's quite disheartening after reading so many positive reviews about this drug. My doctor recommended giving it more time to take effect, but I'm losing hope."

1 / 10
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  • Mon...
  • July 28, 2015

"For me, it was awful. I was on this pill for 7 days. I went to the doctor today because my heart was beating so fast on these pills, and I was paranoid, anxious, shaking, and very, very b---hy. I thought I was having a heart attack at work. I was crying, it was awful. I went to the doctor, and I couldn't get words out. My pulse was 115, and blood pressure was high (never ever is), it just shot up. The doctor said I was having a panic attack and that it is due to the medication. She took me off it, and for the next 5 days, I am on Lorazepam 0.5 mg (sedative to calm me down - take it at night) and switching me back to sertraline. This was the worst experience of my life. I thought I was going to end up in the ER or dead."

1 / 10
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  • nat...
  • Taken for less than 1 month
  • October 30, 2016

"Do not take this medication if you have a pre-existing anxiety disorder... even if you are on a benzo or buspirone before starting it. My anxiety was well controlled with an SSRI and buspirone, but my depression did not seem to be getting any better. My psychiatrist tried switching me from the SSRI to 100 mg Wellbutrin SR. I could only take the Wellbutrin for 6 days. It gave me horrible panic attacks, racing heartbeat, and severe sweating. I have no doubt it may work well for depression, but it is a bad drug to try if you have depression and generalized anxiety disorder. I am now back on the SSRI. I would rather deal with some depression than have panic attacks!"

1 / 10
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  • Coa...
  • July 6, 2015

"I've been on Wellbutrin for 2 weeks, and I don't really feel any better. I notice weight gain and more irritability than usual. I've read that I must be patient and continue taking it, and I should see improvement after about a month. I took this years ago, and it was the reason I was able to quit smoking. My wife called it the happy pill because she saw a big difference in my mood. So far, it's not having the same effect it did 15 years ago. I do like that I am not having any other side effects. My sex drive is still good, and I think my anxiety has improved somewhat. I'm on 100 mg a day, and I take it first thing in the morning."

4 / 10
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  • wor...
  • September 4, 2009

"Wellbutrin is the only antidepressant that has worked for me. I've tried 7 other kinds, and all made me worse. Wellbutrin's initial side effects were mild, mainly headache and nausea. But I noticed I was happier and more worry-free after a few weeks. I have to admit that this medicine made my appetite worse. I know it's sometimes prescribed to help with obesity, but it made me gain weight. If you are a smoker, be careful because it will make you sick if you smoke, which is why I was able to quit smoking."

8 / 10
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  • Brv...
  • January 7, 2017

"My doctor started me on a very low dose of this (100 mg). I have anxiety, depression, and (a questionable diagnosis, pending review) of bipolar disorder. The first day I took this, I had a full-blown panic attack. My heart was racing so fast, and I was experiencing pretty bad chest pain and heaviness, so much so that I called the office and they wanted me to stop taking it and go to the ER to have an EKG done. I stopped taking it for about 2 weeks, but wasn't ready to give up on it - big mistake. So I went back on it for 3 days. Each day I had an elevated heart rate and felt anxious all day long. I was EXTREMELY irritable to the point of rage, my ENTIRE face broke out with painful cystic acne I'd never had before - basically overnight. Skip!"

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.