Wellbutrin and Dry Mouth: What Users Say (Page 2)

• Anonymous
• February 26, 2017

For Depression "Wellbutrin worked very effectively in treating my depression. It lifted me out of a major depression I had been in for years. However, I am facing an issue because while Wellbutrin is great for treating my depression, the side effects are terrible. I am having excessive sweating all the time and extreme dry mouth. The dry mouth is causing bad breath and cavities. I am doing everything I can to combat the dry mouth and sweating with no avail. I was told the side effects will diminish over time, but it has been over a year and the side effects aren't any better. Does anyone know of effective ways to combat the side effects?"

• Toy...
• January 20, 2010

For Bipolar Disorder "I have been annoyed all the time since I can remember. Always a pessimist. I figured if I expected the worst possible scenario, anything better was a win. It was as if I was at war with the world, everything was a battle. I've been on Wellbutrin for 6 weeks now, 300 mg a day in 2 doses to start. It gave me ridiculously bad headaches (I suffer from migraines already), but my mood, interest, and general sense of well-being were better. My doctor changed me from 2 doses to 3 doses a day (still 300 mg). No more headaches but slight insomnia so far: 3-4 hours a night now, usually getting 6-7 hours of sleep. And I have dry mouth as well. I will deal with the insomnia and cotton mouth. To me, this is worth it."

• Meg...
• Taken for 2 to 5 years
• January 13, 2020

For Depression "This medication was a miracle for me in the beginning. The only side effect I had was weight loss, which was an added benefit for me. It worked great for 3 years. I had to up my dosage from 300 to 450 once while I was going through some extra tough stuff, but I eventually lowered it back down to 300 mg. I recently moved to a different country, and very suddenly I had the WORST dry mouth! My teeth were literally rotting out of my mouth, and I couldn’t figure out why. Constipation was so bad, I’d be backed up for weeks and on the verge of going to the hospital. This medication is hard to obtain in this new country I moved to, so I had to switch, which I was sad about until I stopped taking it and the dry mouth and constipation subsided. What the actual heck?!"

• Ean...
• January 31, 2021

For Depression "I took generic Bupropion 150 XL from Dr. Reddy Pharmaceutical for 10 days. My doctor said there were no serious side effects. I might have dry mouth, she said, but it'll help with your loss of energy. The first two days, I certainly had dry mouth (and increased urination), maybe a little more energy, but on day 3, I started experiencing flu-like symptoms, awful body aches, diarrhea, vomiting, profuse sweating. I felt terrible! To make matters worse, my normally low heart rate (around 50 beats per minute) skyrocketed to 130-140. I felt delirious, and I immediately went off of it. I almost went to the ER, but I decided to stay home and monitor my own symptoms as I'm in healthcare myself. Currently, day two off of it, but I am still experiencing flu-like symptoms and now eye pain with dizziness. Thankfully, my heart rate is slowly going down. My biggest concern is with people who have high blood pressure. Do not go on this medication. Try a different one. These side effects are not worth it."

• ver...
• November 7, 2009

For Depression "I have been taking this medicine for over a week, and I do feel much more motivated and an overall sense of well-being. Side effects I have come across are dry mouth, or being thirsty - which helps to prevent any headaches. Early on, there was difficulty sleeping, but that comes and goes. I feel a little disoriented when I do wake up. Bowel movements actually improved. I don't recommend drinking while taking this. This was my first antidepressant, and I am very happy with the results so far!"

• Sun...
• Taken for 1 to 6 months
• August 8, 2021

For Depression "I have found Wellbutrin to be the best for me. I've tried Zoloft, Lexapro, Cymbalta, Adderall, Vyvanse, Prozac, and Strattera. These others made me too agitated or too zombie-like. No dry mouth, no jaw clenching, no yawning, no RLS, no anxiousness, no headaches with Wellbutrin/Bupropion. Feel uplifted, more my old self, laugh and love easier, and anxiety a bit better. Less achy too! My long-term memory has even improved. I don't mind the vivid dreams, kind of fun. I do have some side effects which make me wish and plead for a lower dosage to be available. I'm taking 150 XL here in the USA. I really wish they'd make a 75 XL for sensitive types like me. I often get into a hyperfocus mode with this dosage of Wellbutrin. I can get a ton of reading done, internet research, etc., but then procrastinate things of higher priority. Please, manufacturers, please offer 75 XL as well. I think you'd be helping a ton of people."

• Use...
• Taken for 6 months to 1 year
• January 23, 2020

For Major Depressive Disorder "Does nothing for depression. Dried me out to the point of needing steroid eye drops and regular eye drops every 4 hours. I would also wake up every night with a dry mouth. Don't take if you have insomnia. More of my life wasted trying potions."

• TDi...
• January 20, 2010

For Depression "I have suffered from severe depression for over 3 years, mood swings, irritability, loss of interest, huge lack of energy, absolutely no motivation, anxiety, paranoia, and panic attacks. I was prescribed 100 mg extended release 2 times daily, and it's amazing how quickly it works. I don't have nearly as many mood swings as before, I have tons of energy (once you are on Wellbutrin, you realize just how much depression really affects you without even noticing it), tons of motivation. (I used to debate whether I should do this or that, now I just do it, there's no question whatsoever). However, it did not help my anxiety or panic attacks. The side effects for me were a very annoying twitching and dry mouth. I have only been on it for a week, so time will tell."

• KAD...
• May 23, 2018

For Depression "I was on Prozac 20 mg, and because it made me feel so good, I would just stop taking them on my own accord, which made me crash. I decided instead of taking them seriously and continuing to take them, I would try Wellbutrin. The first two weeks were awful. I had ringing in my ears to the point where I wished I was deaf. My body was incredibly sore for no physical reason. I felt huge pressure and anxiety in my chest. I stopped working out and didn't want to do anything but lay in bed and watch Netflix, which is so not me. I am now 3-4 weeks in, and I don't have much anxiety, BUT I feel like I developed OCD. I can't stop cutting the tip of my tongue on my teeth, and it hurts. My mouth is so dry. I can't even put on eyeliner because it's like I have Parkinson's disease. I am going to switch back to Prozac today."

• Alw...
• August 28, 2014

For Major Depressive Disorder "I have been taking Wellbutrin for 10 months. I had 6 migraines in the first 10 days, but then the headaches stopped. I also had dry mouth for about a week when I started taking the 300 milligram tablet. After that, no side effects at all. Unfortunately, I have had no positive effects either. I feel as though I am taking a sugar pill. I am still dysthymic all the time and have had several depressive episodes lasting weeks since beginning this medication. I agreed to take it for a year, but I don't see any improvement at all."

• Not...
• Taken for less than 1 month
• April 2, 2018

For Depression "I experienced most of the side effects, thankfully, I didn’t have a seizure. I’ve been off a few days and am still having side effects. Made my heart race, chest hurt, chest pressure, dry mouth, and forgetting everything. This medicine, did however, help my depressed laziness. I had the get up and go and wanted this med to work because it gave me that. My chest still feels like a hippo is sitting on it."

• Anonymous
• April 27, 2011

For Anxiety "I was put on a 150 mg dose about 4 weeks ago for mild depression/anxiety. I had dry mouth, headaches, spacey feeling, and nervousness, all of which added to my anxiety. I switched to 300 mg for 1 week, but the jitters increased, and I could have climbed the walls! Rarely felt like eating. It did not negatively affect my ability to orgasm (like Lexapro did), which was nice, but couldn't handle the side effects. Trying Cymbalta."

• wan...
• Taken for less than 1 month
• November 28, 2015

For Major Depressive Disorder "I've been on bupropion 150 SR once a day for 8 days. So far, I'm only feeling side effects: dry mouth, sweating, jaw clenching. It has not lifted my depression or energized me. Celexa and Zoloft used to work for me but then slowly stopped working. I'll try to stick it out for a few more days. I was really hoping that this med would work for me. I feel that I may be drug-resistant to A/Ds. I also take 1 mg Klonopin to sleep and to lower anxiety."

• Anonymous
• January 13, 2010

For Depression "31 years old and have never taken any kind of medication other than birth control. Recently went through some tough stuff and finally broke down after almost a year of feeling terrible and talked to my doctor. Started taking Wellbutrin about a month ago, and I haven't felt this good in years. I started feeling better almost immediately. I am motivated and focused and like my old self again. In addition, I stopped smoking completely about a week after I first started taking it. Only negatives are I am having a REALLY hard time getting enough sleep, and the dry mouth is bad but only on occasion. I really hope that the insomnia gets better because although I feel great, I know it can't be good to have such little sleep long term."

• ADH...
• Taken for 6 months to 1 year
• September 22, 2021

"I have Attention Deficit/Hyperactive Disorder. I’ve tried SSRIs, Abilify, and Lamictal before, and while they did help somewhat with depression, they did not help with executive function and enjoyment of hobbies/interests in the way that Wellbutrin does. As for side effects, it does cause a bit of dry mouth and lack of appetite for water (especially if combined with Ritalin). I have lost 15-20 lbs on it in 8 months, but I think that’s not the drug so much as because food is no longer my main source of dopamine; I’m not eating more than I need to anymore. The first week, I had sensory experiences in dreams I didn’t think I could have (temperatures, textures, complex emotions, etc.). They weren’t all nightmares; most of them were kinda fun and cool actually, but they were a little disorienting when I woke up. That went away though within a week and only happens now if I take it right before I go to bed or nap during the day. Even then, the dreams are really not as vivid as when I started it."