Wellbutrin for Depression User Reviews (Page 2)

• Anonymous
• Taken for less than 1 month
• November 8, 2022

"Almost quit taking it at first because of the headaches, insomnia, fatigue, and anger, but kept on taking it, and 2 weeks later, I’m happier, have more energy, I’m actually sleeping better than before I took it, and no longer angry. Really thankful for this medication. (P.S. Was taking 150 XL mg but didn’t notice the drastic change until I got on 300 XL mg.)"

• hop...
• May 23, 2010

"I have taken Paxil, Effexor, and Lexapro. These drugs helped but left me feeling like a zombie, had sexual side effects, and extreme night sweats. Because of these side effects, I always went off the prescription after a year or less. When I went off Effexor, I was energetic, worked out, and felt great. I thought if I could just maintain working out, I would be okay. Well, I slowly quit working out and got angrier and angrier. I tried to fight it for 3 years before I couldn't take it anymore. This time, the doctor put me on 150 mg Wellbutrin XL. I started feeling better within a couple of days. I did experience bad headaches and had an upset stomach for the first month. It was worth it. I have no side effects and feel 100% normal."

• Anonymous
• April 29, 2012

"I started off on the Wellbutrin 150 mg XL twice a day, and I was exhausted every day, not to mention the nausea was so bad I had to stop taking it. Just started on Wellbutrin immediate release at 100 mg once a day, and it is a complete difference. I have so much more energy and focus, so far I love it. I do get a little headache by the end of the day, but it's not a big deal."

• Anonymous
• November 23, 2009

"I've been taking Wellbutrin for about 1 month. I really want this medication to work, but I'm having all side effects. Started with a bad taste in my mouth and went to headache, really dizzy, and nauseous. (I will go off if this doesn't go away.) Today I'm having some chest pain, but it feels a little worse than the anxiety chest pain I was having, so I'm not sure what to think of that. I have been on Prozac and then Celexa for 10 years, and I wanted to try this for the less sexual side effects. That has worked, and I feel more sensitive to the things that should make you cry. I really want this to work, but the side effects are hard. I'll stick with it and hope they go away soon."

• Bip...
• Taken for 1 to 6 months
• March 12, 2019

"I have bipolar II, and after a series of failed drugs, I was prescribed quetiapine (that's a whole other message board) and bupropion. I was on Activas bupropion 150 XL for about six weeks. It stabilized me, but I was still depressed - but functioning. Side effects - waking up early, feeling like a zombie, loss of appetite - went away within that time period. I've now been on Par Pharmaceutical's bupropion 300 XL for about a month. Side effects are irritability and jitters, but I'm hoping those go away. I tried Activas 300 XL - oval pills - and it seemed to dump a large portion of the medication about two hours after taking it, giving me a zombie effect. It also gave me a headache. Those things may have gone away with time, but I switched back to Par. Overall, I'm content, and my depression is gone."

• D S...
• Taken for less than 1 month
• January 29, 2021

"Since when it comes to this type of medication, it works like a dream for one and a disaster for another, I rarely read these reviews. I have never left one either. But my experience with this one was not good. Hopefully, for those who experienced sickness, hard depression, whacked anxiety, dizziness, sick headaches, sleeplessness, zero appetite, head pressure, and pure insomnia, maybe this review will give you hope as you are not alone. I was going to try to get through it, but no way. Garbage. After 1 week, I bailed out. Purely awful for me."

• MyE...
• Taken for less than 1 month
• March 8, 2017

"Unfortunately, this medication did not work out well for me at all. I was on 150 mg of Wellbutrin, a generic SR version. In the first week, I took the medicine first thing in the morning as directed (for me, that's about 7 a.m.), and the rest of the day I had intense/severe headaches. Mind you, I already take medication daily for migraines because I'm a chronic sufferer, and my migraine medication was being blown out of the water! I felt like I had several ice picks in my head. The other issue I noticed immediately was that I was having an extremely difficult time sleeping, and if I did fall asleep, I'd have very vivid and awful nightmares. Other apparent issues were having memory loss and abnormal behavior. Not for me!!!"

• Anonymous
• February 20, 2011

"This is my second time on Wellbutrin XL. I took it once when I was 14-15, with no negative side effects, and I'm now 18. My doctor started me on 150 mg and then bumped me up to 300 mg, and it helped so much. This time when I started, I got headaches for the first 10 days, which were pretty bad sometimes, but it was worth sticking them out (I had headaches during depression anyway). And for a period of 1-2 weeks, I would wake up in the middle of the night for no reason, but I could usually always go back to sleep. I have more energy, and I don't dwell on things as much. Overall, very satisfied."

• Rid...
• Taken for 1 to 2 years
• February 21, 2021

"Anxiety was a way of life, but now my Dr. prescribed 150 mg time-released. Flowers for Algernon and enhanced sex drive all in one. My work performance hasn't been this good in years-I'm near the end of my career, and I'm sharp and concise as ever. Hot Wife and I are having college-style sex, and it's been a long time since we have set foot on campus. Side effects are fatigue and occasional headache, but overall, the joy of life and the five senses we have are better than ever."

• Sqy...
• Taken for 1 to 6 months
• November 11, 2017

"The first few days while taking Wellbutrin, which is not really recommended for anxiety, but the doc recommended giving it a try, were not too bad. Around week 2, I began to notice I was miserable, angry all the time, and just not feeling like myself! I am usually a happy person that laughs a lot and enjoys making others laugh! Wellbutrin changed all that! I was now a bitter and angry person that found fault with everything! I wasn't sleeping well, had slight headaches every day, and my head felt cloudy and foggy all the time! I wasn't able to concentrate, which made it difficult for me to function properly at work. I was no longer the happy, silly person I used to be! This drug totally changed my personality!"

• jmm...
• April 15, 2015

"I was diagnosed with severe depression and anxiety, as well as a bit of OCD regarding my weight well over 10 years ago, but started taking medication for it only 2 years ago. I'm on Wellbutrin again, after a year or so off of it, for about 6 days now, and I haven't felt much of a positive change whatsoever, unfortunately. The one side effect I've been getting is extreme migraines. I suffer from chronic migraines anyway, but they're never usually this bad every day. I'm not sure if it's because I'm still coming off of the Zoloft while starting up the Wellbutrin. Zoloft gave me awful headaches and major weight gain along with some insomnia. I'm sticking it out and hoping that the migraines go away. I have been nauseous daily also."

• Anonymous
• January 19, 2011

"Just started taking this for depression/anxiety, so far, so good. The first few days, I could definitely feel the stimulant effect, but on day 5, I can barely feel anything. Obviously, it's too early to tell how it will help with anxiety/depression. I had just a hint of a headache, but nothing bad enough to even take anything for. No real trouble sleeping. I will be increasing the 150 mg to 300 mg (twice daily) Saturday, so I'm sure there will be another adjustment period then. I've heard it's important to take the second dose fairly early in the afternoon (around 3 or 4), so it doesn't keep you up. At first, I did not think this would work with my anxiety, but it's mostly gone due to my body adjusting."

• Ann...
• Taken for 1 to 6 months
• March 22, 2018

"First off, I really don't know why my therapist insisted that I start this medication. I had some depression, but this was primarily due to situations in my life, NOT due to a chemical imbalance. I have never experienced depression before, and my family has no history of depression. When I first took this medication, I had a major headache, and this was my first in about three years. My therapist said this would pass, and it did. I went for my regular workout, and I felt a bit more sore than usual afterwards, but dismissed it. I woke up in the middle of the night due to severe muscle/tendon pain and had to take acetaminophen to get to sleep. My therapist said the pain would go away, and it did. At least until my next workout. During the night, I must have woken up about five times, I was in such pain. I got off the medication, and in about two weeks, the muscle/joint pain was gone. If you are on this medication, you cannot work out, even though studies show exercise helps with depression."

• Lad...
• Taken for less than 1 month
• February 5, 2018

"Started bupropion XR 150 for depression and ADD. Took it once in the morning at 8:00 a.m. for only two days. On the first day, got very sleepy two hours after taking it, I got a mild headache and very sleepy at night, slept okay, crazy dreams. Second day, no headache, felt no energy but just drive to do whatever needed to be done through the day, dishes, laundry, etc. Second night, I began to itch. My arms, back, top of head, and noticed my asthma started to flare up. So I decided to discontinue use in fear of allergic reaction. Did not want to have a major reaction or get the welts and worse rashes I’ve heard of. So far, took last dose on a Thursday and today is Monday, so four days off. No major withdrawals or signs, but I just feel really good as the days go on. Did the two days knock my brain out of depression? Hopefully, I can add more comments in a few days to see what happens within the next week and so forth."

• Ogo...
• Taken for 1 to 6 months
• September 23, 2012

"Horrible side effects: irritability, headaches, malaise. Did not help me with depression as a result."

• qua...
• Taken for 1 to 2 years
• August 4, 2012

"When I first took it, I thought it was great, but after being on it awhile, I got terrible headaches, and if you ever got angry while on it, my blood pressure went real high."