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Bupropion for Depression User Reviews (Page 4)

Brand names: Wellbutrin XL, Wellbutrin SR, Aplenzin, Budeprion Forfivo XL Budeprion SR

Bupropion has an average rating of 7.0 out of 10 from a total of 1285 reviews for the treatment of Depression. 60% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Bupropion

  • abme
  • Taken for 6 months to 1 year
  • July 15, 2022

"I'm on Zoloft 200mg and Bupropion 300mg. I've always had a high sex drive and not even the Zoloft caused that to go down, which was great. However, I am mad about the fact that when I got on Bupropion my sex drive has dramatically diminished and the worst part is I cannot climax. I'm lucky if I can get 1 orgasm with 1.5hrs of masturbating versus the multiple/fast orgasms I used to. I've tried it for over 7 months now and I'm about to call it quits (after talking with my doctor first which seems weird to say "hey doc I've never spoken to you about this before but I CAN'T orgasm and I want to be off of this med."

7 / 10
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  • Statu...
  • Taken for less than 1 month
  • July 4, 2022

Wellbutrin XL (bupropion) "I went into this endeavour quite excited, knowing that there would be some compromises as always and I was ready to trade. But this drug took away everything for itself. I was taking Zoloft and upon me complaining about feeling well, but not being motivated (probably I got used to SSRI's a little bit) to get my butt up and get stuff done, smoking 1.5 packs/day and of course, to combat SSRI SD, we agreed on trying Welloft (Z 75mg - W 150mg) I've been taking Wellbutrin for exactly 20 days, and it's been a big disappointment. I definitely intend to take it for 2 months and know for sure if it's for me or not — not a day longer! Increased anxiety, aggression, appetite, insomnia, difficulty concentrating and short term memory issues, worse depression, chest pain, headache. Severe climbing anxiety till it peaked at day 8, then I would have bad one sporadically. I would consider myself almost impotent now. I remember Paxil days with a smile. Will update if anything changes at 2 month mark"

1 / 10
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  • Metap...
  • Taken for less than 1 month
  • July 4, 2022

Wellbutrin (bupropion) "3 weeks in; I’m a huge believer in Wellbutrin now, it truly was a great decision for me to start taking it for Depression, Anxiety, & ADHD. Surprisingly, haven’t experienced any side effects! My daily depression went from being on straight 10 down to a 1-2. Anxiety is the more debilitating aspect of my mental health though; and it certainly has lowered my anxiety levels also. I’m much less anxious. Wellbutrin is mildly stimulating, especially when compared to other treatment options like SSRI’s. It’s better than any SSRI I’ve ever tried, SSRI make me feel flat and dull. Wellbutrin actually makes me feel happy, when I smile or crack a laugh I feel it helping me truly feel joy which was a forgotten feeling prior. My ADHD symptoms are better while on it. It helped me quit vaping nicotine! I also have slow down on marijuana as well, which I was only a casual user prior, but still, Wellbutrin definitely helps with quitting marijuana too! Give it a try! I hope that your experience is like mine"

10 / 10
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Frequently asked questions

  • Josh
  • Taken for 1 to 6 months
  • June 15, 2022

"I tried Bupropion/Wellbutrin since I didn't react well to SSRIs/SSNIs. I can tell the first 4 weeks was pure nightmare: no sleep, no appetite, panic attacks, terrible anxiety feeling sick all day. But after that it became much better. Suddenly I started to notice that I had a lot more energy, I had more self-confidence, my social anxiety was better so I got back most of my motivation and old life. And.. most importantly instead of the lack of libido I had increased sex drive ! So far perfect right? Well unfortunately not really but overall it is indeed a good medicine. The reason why I decided to stop taking it after 3 months was that some of the stubborn side effects stayed : after months I still couldn't fall asleep, I was drastically loosing weight, I became aggressive and sometimes paranoid and my anxiety showed only minor improvements. If you have anxiety forget it, for depresison it is worth a try but there is a reason that this is the last medicine you are prescribed."

6 / 10
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  • judon...
  • Taken for 1 to 6 months
  • June 11, 2022

Wellbutrin (bupropion) "I've had moderate depression and some anxiety most of my life. It manifests mostly in the forms of low energy, worrying, irritability, and avoidance. Dishes piling up, laundry not getting done, car interior a mess, etc. I tried two SSRI's (Lexapro & Zoloft) before switching to Wellbutrin, which is Dopamine Reuptake Inhibitor. Dopamine! That was the answer. It wasn't a serotonin problem, it was a dopamine one! The SSRI's worked ok, but I was always tired and foggy. I gave each 6 months. I eased off the SSRI and eased into the Wellbutrin. I only take 150mg at the moment. I'm almost 4 months in, and I can't believe the improvement. I bound out of bed in the morning and start getting stuff done. My attitude is positive, excited, eager for the day and being alive. I can't believe it. All those years with the background hum of depression, even if mild at times, made me think feeling that way was normal. It wasn't! This turned out to be the perfect fit for me."

10 / 10
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Are you taking this medicine?

  • Anonymous
  • Taken for 1 to 6 months
  • June 11, 2022

Wellbutrin (bupropion) "Doctor started me on Wellbutrin 150mg once daily for ADHD and depression and I must say this drug takes about 3 weeks to start working. At first I was frustrated but continued taking it. I experience weight loss, a boost of energy, and motivation in my everyday life. I was out on 300 mg daily and it was a little anxiety, fast heart rate at first then after a few hours it goes away. I was told this is normal."

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  • Ron
  • Taken for less than 1 month
  • June 9, 2022

"I'm putting this review for warning also. I have never felt suicide feelings like I have when I took this 150mg x 2. It was overwhelming . Also shaky hands, a taste of grossness that permeated out of me. I felt I was losing my mind at work once, with hints of rage under my skin. It gave me hardly any sleep. I couldn't stop taking this fast enough. I only took for a week."

1 / 10
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  • Avery
  • Taken for less than 1 month
  • June 8, 2022

Wellbutrin XL (bupropion) "I have been on this medication for four days and I am weeping because of how good it makes me feel. I have been medicated for a long time and this is the first time I don’t feel like garbage. I have energy, motivation, clarity, peace, I didn’t know that was possible for me. I had my first suicide attempt at eight years old and this is the first time I’ve ever felt actual genuine relief from my stress and adhd. I love being alive now and I didn’t think I could. I love this med so much."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • June 5, 2022

Wellbutrin XL (bupropion) "This medication works awesome for my depression. I’ve tried a lot of different antidepressants and this one is good."

10 / 10
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  • MommyMe
  • Taken for less than 1 month
  • June 3, 2022

Wellbutrin XL (bupropion) "I enjoyed it until after about 2 weeks there was a side effect that ruined it for me. Throat tightening! It felt like when I’d swallow my food or vitamins and they wouldn’t go down . All day! Once I tapered off of it the side effects definitely subsided. But it seemed to be worsening so I could not continue it. But aside from that I really loved the med and this was super rare according to my dr."

5 / 10
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  • BiPol...
  • Taken for 1 to 2 years
  • June 2, 2022

Wellbutrin (bupropion) "I have had great success with Wellbutrin. It has helped me quit smoking twice. I feel it supports an upbeat mood without being over stimulating. I get good energy from Wellbutrin. I also like that there are no sexual side effects, no weight gain, and no noticeable withdrawal syndrome. Highly recommend Wellbutrin (bupropion!)"

10 / 10
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  • BaeCe...
  • Taken for 1 to 6 months
  • June 1, 2022

"I have been taking this medication for 6 weeks, and I have noticed a drastic difference in my mental health. I no longer care as much about peoples opinion or when I'm driving or someone does something stupid, I don't dwell on small things like that with the same intensity I used to without medication. As far as side effects go I have noticed that sometimes when I get into a tense situation at work or while driving my heart will beat really fast to the point that it hurts. That is about the only major negative side effect I have noticed. Some of the minor side effects include dry mouth, slight memory loss, mild constipation, etc. I didn't really experience insomnia, increase/decrease in weight/appetite nor any changes to my libido. This is all fine since I am at my desired weight goal and my libido had been fine prior to taking this medication. I definitely think its worth a shot, the way I see it, there's only failure in not trying it."

8 / 10
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  • Rozzie
  • Taken for 1 to 6 months
  • May 16, 2022

Budeprion XL (bupropion) "Started out okay on 150mg. Moved up to 300mg. Okay at first, then after a few months, side effects kicked in. My memory was getting much worse, balance was off. Hard time walking straight. I was in bad shape. It's hard to get in to see the doctor, so I quit taking them completely. Within two weeks I was back to my old self. Never again!"

1 / 10
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  • Anonymous
  • Taken for 10 years or more
  • May 9, 2022

"I've been on Bupropion XR for nearly 10 years with little to no side effects. About 2 years ago, it was starting to lose its effect, whether due to my body getting used to the medication or events in my life, my doctor increased my dosage from 300mg to 450mg and that is working very well. I still have the occasional sad, stay-in-bed-all-day, days, but they are pretty rare."

10 / 10
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  • Bill
  • Taken for 1 to 6 months
  • April 30, 2022

Budeprion SR (bupropion) "One of the first drugs I was given, worked for exactly one day after I had been on it for 3 weeks. Not a slow improvement, just one day it worked, the next it didn’t and it never changed anything again."

3 / 10
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  • Stunned
  • Taken for less than 1 month
  • April 21, 2022

Wellbutrin (bupropion) "This drug made me nuts. I took it for anxiety & depression, and it multiplied the anxiety by a factor of 10. It was like a hand reached down from the sky, grabbed me by the throat, and scared me witless. I could not calm myself down. I felt doomed. I was so scared I became jumpy & angry. Like, furious. The literature all says these symptoms may fade, so I kept taking the pills for 2 weeks until my husband was exhausted by this frantic woman I had become. I stopped cold, and felt normal again almost immediately. So do t feel you have to stay with it!"

1 / 10
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  • Thank...
  • Taken for 1 to 6 months
  • April 12, 2022

"I was diagnosed with clinical depression at a very young age and tried several anti depressants (ssri’s) but I didn’t want the side effects of being on an antidepressant. I tried everything natural and holistic. I had my hormones checked I eat super healthy, exercise and I don’t drink Alcohol. It all helps for sure but I still had that overall depression super low energy, no motivation and anxiety. I couldn’t take it anymore so I decided to try Wellbutrin (bupropion) because it’s supposed to help with energy and focus. I noticed I had more energy and focus within a week or two and I did have some side effects that were strange. Weird dreams and some anxiety for a few days. I started with the lowest dose 150mg for 3 weeks and then moved to 300mg. Within 8-10 weeks I started feeling the full effect. It has been 5 months now! I am able to get through the hard times quicker and be more positive all around. I am so grateful for this medication."

10 / 10
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  • Denta...
  • Taken for 1 to 6 months
  • April 10, 2022

"I started taking Wellbutrin 150mg a few months ago and I saw improvements with my mood and energy. I started doing things I stopped doing. Increased to 300mg a day because it was at a stand still I felt a lil better, but only sometimes. After the increase I felt great. My heart would beat fast a little but that stopped. I have noticed a huge increase in my sex drive. I get turned on so easy, and think about sex a LOT. My husband isn't complaining, especially since I'm kinda shy. During sex, I feel like there is more, wetness. It is great, BUT I feel like I am about to orgasm and I never get there. It's like you are there but it never comes. It's this happening with anyone else?"

10 / 10
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  • Momo
  • Taken for less than 1 month
  • March 22, 2022

"This medication helped my depression but completely revved up my anxiety. I didn’t notice it until I was in the ER with panic attacks."

1 / 10
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  • Dave
  • Taken for 1 to 6 months
  • March 11, 2022

Wellbutrin XL (bupropion) "I started Bupropion in Jan 2022. I was diagnosed in 2007 with Bipolar II Disorder, but also have, Depression, Anxiety, ADHD. I have been on various antipsychotics & SSRI/SSNRI antidepressants for at least twenty years. My depression has always been problematic. I have achieved significant relief with my current medicine regimen, which is Sertraline 100mg x1, Lamotrigine 250 mg x1, and Bupropion 450mg daily. I titrated up Bupropion XL from 150mg to 450mg over the course of two weeks. Side effects first included severe constipation, headaches, stomach ache, & an increase in anxiety. After about two weeks, those side effects abated. When I up it to 300mg, I developed some leg restlessness ( not Akithisia), which abated in about three days. When I titrated up to 450mg, I developed diarrhea for three days. I am now on the 450s with no serious side effects. For me, the Bupropion only started working when I reached 450mg. Although it has not been a game changer, I feel that it safely & effectively complements my other meds."

7 / 10
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  • Mr Pa...
  • Taken for 1 to 6 months
  • March 8, 2022

Wellbutrin (bupropion) "Started Wellbutrin XL 6 weeks ago after having depression and constant anxiety and bad side effects on SSRI’s. First 2 weeks I didn’t notice much or have any side effects. Week 3 my anxiety was the worst I ever experienced and at points I felt like I was having a heart attack. This side effect subsided after a week and left me feeling better than ever. No depression whatsoever, and my anxiety is at a normal and manageable level. I Feel normal for the first time in years, this medication saved my life. It takes time to have a full effect so be patient."

9 / 10
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  • alice
  • Taken for 1 to 2 years
  • March 7, 2022

"Least amount of side effects and it increased my sex drive. It made my period come more frequent tho which is interesting"

10 / 10
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  • Bryan
  • Taken for less than 1 month
  • March 7, 2022

Wellbutrin XL (bupropion) "I started wellbutrin xl 150mg about a month ago. I didn't really have any negative side effects. Just a little harder to fall asleep. When I started taking it I immediately had more energy, didn't want to vape, and ate way less. I never felt hungry. The past week it seems like it's not as effective. I'm eating and vaping like normal and not as much energy but still better than without it. Thinking about asking for a dose increase."

8 / 10
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  • space
  • Taken for 1 to 6 months
  • March 1, 2022

"This drug took 4 months. I started in October at 150 mg and slowly increased to 300mg. At 300mg I feel great!! I have been waking up and making myself breakfast. I am not having random crying and sadness spells. After trying 3 other drugs, I am so glad I found this"

9 / 10
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  • renat...
  • Taken for less than 1 month
  • February 26, 2022

"I am second week now, dose 300 mg and I feel it's not helping with depression, but anxiety get worse. I can't go out from my house now."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.