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Bupropion / dextromethorphan User Reviews & Ratings (Page 4)

Brand names: Auvelity

Bupropion / dextromethorphan has an average rating of 8.3 out of 10 from a total of 96 reviews on Drugs.com. 78% of reviewers reported a positive experience, while 8% reported a negative experience.

Reviews for Bupropion / dextromethorphan

  • Sarah
  • Taken for 1 to 6 months
  • October 8, 2023

Auvelity (bupropion / dextromethorphan) "This saved my life literally. Zero side effects noted even on the first day. I never leave any kind of medication reviews but wanted people to know, as this is a new medication, that there is hope. Two weeks in and things didn't seem so hard. Four weeks in and I felt like a normal person."

9 / 10
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10 Report
  • CTCin
  • Taken for less than 1 month
  • April 24, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "For reference, I’ve been on Wellbutrin and Effexor for several years. I stopped the Wellbutrin when starting Auvelity and I just started weaning off the Effexor this weekend, so it’s too early to tell. However, since I do feel “lighter” already I’m hopeful. The first couple of days at the full dose caused some dizziness and mania about two hours after taking but both have decreased. I took the second dose a little later last night and now I feel extreme fatigue so I’m going to be more diligent about taking it earlier. The doctor said the side effects should go away soon so I’ll update here. Again, I’m hopeful!"

8 / 10
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14 Report
  • hatem...
  • Taken for 6 months to 1 year
  • March 13, 2024

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I was on one Auvelity a day (45mg) even though the doctor had prescribed two a day for me. About 8 months after taking one a day, I felt my depression getting worse, so I told my doctor I would take two, his original prescription dosage. Two and a half to three weeks later, I have been experiencing much increased anxiety, feelings of discomfort and restlessness/nervousness, extreme agitation and fear. I did not know what was wrong with me until I decided to look up Auvelity side effects, which is why I will be going back to one tomorrow and calling my doctor. Another disappointment from the medical community that causes more problems."

6 / 10
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5 Report

Frequently asked questions

  • Chron...
  • Taken for less than 1 month
  • September 23, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I have been on a variety of antidepressants for the past 15 years. I started Effexor about 6 months ago, and it was life-changing, but I still had depression and my anxiety was paralyzing. My psychiatrist put me on Klonopin for anxiety and Auvelity for depression. I was very hopeful this would be the combination that would allow me to function. The first week, I felt amazing despite having intense nausea and generally feeling kinda loopy like being on a pain pill. By week 2, those side effects went away. Now, I can’t wake up and can’t stay awake during the day. At first, it was just general tiredness, but now I fall asleep throughout the day, including while driving, regardless of how much caffeine I have had to help me stay awake. Although my depression has decreased, I go through intense and unexpected mood swings. I can be extremely happy and excited about an upcoming event and then randomly fall into a deep depression while on the way there. After a bit, I’m fine again."

5 / 10
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10 Report
  • Bob
  • Taken for less than 1 month
  • February 10, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "After the fourth day, I developed a violent cough. My doctor instructed me to stop taking the medication, but the frequent dry cough persisted for 2 months I was previously prescribed Wellbutrin 20 years ago, which at that time was the best drug for me and lasted for 13 years before it stopped working"

2 / 10
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15 Report

Are you taking this medicine?

  • momto...
  • Taken for less than 1 month
  • January 22, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I started Auvelity a few days ago. Some background information about me is that I’m on 450 mg of Wellbutrin and 40 mg of Lexapro. Unfortunately, the Wellbutrin or the Lexapro isn’t helping. I’ve been on Wellbutrin for 4 years and Lexapro for 3 years. My question is, have any of you been on Wellbutrin and switched to Auvelity? Doc switched me to one Wellbutrin per day, along with two Auvelity per day. If any of you have had the same experience with this same combination, I’d love to hear about it. I’m curious since Auvelity and Wellbutrin have bupropion in it. Thanks!"

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  • Bipol...
  • Taken for less than 1 month
  • June 8, 2023

Auvelity (bupropion / dextromethorphan) "I've been taking aripiprazole 10mg and lamotrigine 300 mg for bipolar, but I need to add in an antidepressant, so my doctor recommended Auvelity. I've been on it about a week now and am 3 days into the higher dose. I've had fatigue, lightheadedness, tiredness, tingling skin, jaw clenching, and vision problems as side effects. After taking a dose, I usually feel somewhere between tipsy and drunk, which isn't good while you are working. Still, underneath all the side effects, I can feel that it's working. I don't have suicidal thoughts, I don't have intrusive thoughts, and I'm generally calmer. I'm going to stick this out for a little bit as I feel like I'm not far enough into the higher dose to decide to come off of it. I've been fortunate in that I haven't had insomnia (quite the reverse), but I haven't experienced the change in energy or motivation yet. I'm hopeful, however."

6 / 10
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12 Report

More FAQ

  • Ricky
  • Taken for less than 1 month
  • January 8, 2024

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "Started taking this medicine 6 days ago. It started making a difference today because I usually wake up around 3:30 ruminating and very depressed. This morning was much better. I didn't have the negative thoughts as bad and could let go of the rumination. However, after my second dose today, I'm super dizzy and irritable, so I'm hoping that goes away. I had a great day today, and I think it may be working, just not sure if the dizziness is from this medicine or the discontinuation of my Lexapro."

8 / 10
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6 Report
  • Rob
  • Taken for 1 to 6 months
  • May 18, 2024

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "My experience has been a positive one. I have been taking it for a few months now and after trying everything else, Auvelity plus Zoloft works. I'm just curious how everyone is paying for this expensive lifesaver."

9 / 10
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2 Report
  • Sayisha
  • Taken for less than 1 month
  • February 16, 2024

Auvelity (bupropion / dextromethorphan) "I only started taking Auvelity yesterday for treatment-resistant depression. Currently going through TMS now trying to avoid Spravato. Don’t like the feeling of being disassociated; my doctor said give it a week, but I just feel flat, yucky, like I’m just here; my coordination is off, and very irritable—it’s weird to explain. You feel loopy but not euphoric. I finally just got off lamictal. I take Seroquel to sleep, and now on Auvelity. I have my Ativan for anxiety but haven’t needed it. Been diagnosed with PTSD, GAD, and TRD. I’m going to see how it goes. I’ve been on everything in 22 years and nothing has worked. Will check in again in a few weeks."

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  • AnL
  • Taken for 1 to 6 months
  • May 23, 2024

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I started taking Auvelity as a supplement to my antidepressant as I became resistant to treatment. At first, I took one a day. I didn’t see much difference. So, my doc switched to 2 a day. I think it helped. But I started having a very dry mouth. It is affecting me, and I am not sure what to do about that."

8 / 10
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  • hospi...
  • Taken for less than 1 month
  • June 18, 2023

For Major Depressive Disorder "First of all, I didn't take the brand name which costs over $1000 a month. Most people are not aware that dextromethorphan is an over the counter cough suppressant. There is no need to pay the exorbitant price that the pharmaceutical company has set for this drug combination. You just need a prescription for generic buproprion and purchase a sustained release dextromethorphan over the counter. This is what I did, and I felt a difference in my mood on day 2. I am a hospital pharmacist who has tried every antidepressant on the market. I am now treatment resistant and decided to add dextromethorphan to my current antidepressant. I am pleased to report that I have had a positive response. Please don't pay the exorbitant price for the name brand. I am giving this drug combo an 8 out of 10 since I have only been on it for a few days. I will update later."

8 / 10
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  • Amir3...
  • Taken for 1 to 6 months
  • July 2, 2024

Auvelity (bupropion / dextromethorphan) "Auvelity is best for me. I have tried numerous medications, and it helped with anxiety. It also improved my sleep. It is not recommended for those under 22. The dosage is fixed, so please do not increase it as it may cause unwanted side effects."

10 / 10
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  • behin...
  • December 5, 2022

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "This drug is really helping me out and acted in less than 2 weeks."

10 / 10
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43 Report
  • Mary
  • Taken for less than 1 month
  • July 14, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I've been on this drug for 2 weeks and every day is better. I actually get out of bed. I've tried several other rx and over time they go flat. I look forward to my continued improvement."

10 / 10
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25 Report
  • Depre...
  • Taken for less than 1 month
  • November 19, 2022

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "Really great experience, feel a lot better. Have only been taking it for a few weeks though so we’ll see"

10 / 10
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36 Report
  • jako
  • Taken for less than 1 month
  • May 24, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "From the first day, it worked well. It raised my spirits a lot, and gave me energy, calmness, and the desire to do things."

10 / 10
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23 Report
  • Sunny...
  • Taken for less than 1 month
  • December 24, 2022

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I haven't had any side effects. I'm on day 3 and taking it with Lexapro and Hydroxyzine. So far so good."

10 / 10
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28 Report
  • kathun
  • Taken for 1 to 6 months
  • May 31, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I don't get it. I think it's very overrated but that's just my opinion. I am disappointed, too because I really wanted this to be it."

4 / 10
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21 Report
  • garyh...
  • Taken for 1 to 6 months
  • August 29, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "Never felt better, cannot afford. Cost first time $95.00, second $95, third $114, and then off the wall $270.00! I can't afford to take it but I can't do without. Fixed income, 77 years old."

10 / 10
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17 Report
  • jane
  • Taken for 6 months to 1 year
  • June 4, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "Helped with energy, anxiety, and having an interest in life again."

10 / 10
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20 Report
  • Miguel
  • Taken for 1 to 6 months
  • April 21, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "Worked very well on me and from the very first week. Works similarly to ketamine, without the hassle of taking a scheduled drug."

9 / 10
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20 Report
  • Jpal
  • Taken for 1 to 6 months
  • March 18, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "Took for 3 months . Started asking if there were people in the house . Stopped taking and feeling very lightheaded. Did not work for me ."

4 / 10
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21 Report
  • sadas...
  • Taken for less than 1 month
  • December 29, 2022

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I've been on it for a little over a week and I feel great. A little dizziness but that's it."

9 / 10
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19 Report
  • Adriane
  • Taken for 1 to 6 months
  • September 4, 2023

Auvelity (bupropion / dextromethorphan) for Major Depressive Disorder "I love it, only one issue. It does raise my body temperature and I sweat a lot. Other than that, I’m feeling better than I have in years. Doctor did a PA and I pay $35 a month."

9 / 10
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12 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.