Simbrinza User Reviews & Ratings

• Sho...
• Taken for 6 months to 1 year
• April 6, 2018

For Glaucoma, Open Angle "I had a side effect reaction that went on for almost a year before the cause was determined - extremely tired - fell asleep suddenly daily (saw my general practitioner) rapid heart rate (saw a heart specialist), weakness in all my muscles, leg cramps (increased my potassium intake). I saw many doctors regarding my symptoms, including the ophthalmologist that prescribed it to no avail. My local cardiac specialist sent me to a neurophysiologist who assured me my symptoms were not related to my heart - I have a healthy heart. He recommended I either go back to my ophthalmologist (the only doctor that I had seen in the previous 8 months and only source of any medication). My ophthalmologist thought it “might be” the Simbrinza, so ceased my using it. The symptoms lessened over time. I am now seeing an eye specialist. I still have weak muscles, back pain, and stiffness/pain in all my joints. Before this experience, I was a healthy, active athlete. My life has changed completely!!"

• Kar...
• July 25, 2013

For Intraocular Hypertension "Very effective in decreasing eye pressure from 34 to 19 in one week. Side effects started increasing at two weeks, including blurriness, eye discomfort, drowsiness, and syncope. I am stopping Simbrinza on day 15."

• Rud...
• Taken for 6 months to 1 year
• August 28, 2018

For Glaucoma, Open Angle "SIMBRINZA is effective in a significant reduction to normal ocular pressure. But side effects are terrible. I have lost night vision outside and inside my home. I cannot drive at night because the glare from oncoming vehicles is blinding. I am very sensitive to sunlight. I have blurred vision and loss of acuity. I have muscle pain in my legs and arms. I have a dry mouth. Other side effects include low energy, head pain, eye itching, dizziness, eye comfort, and loss of appetite."

• Pok...
• Taken for 6 months to 1 year
• August 28, 2018

For Glaucoma, Open Angle "I've been on glaucoma drops for over 25 years. Without a doubt, Simbrinza is the most obnoxious med I've taken. Here's what I experience with every application: 1. Instantly clouds my vision - usually for a minute or so. 2. Blurs my vision next: this usually lasts about 10 minutes. 3. Burns, but this is the least of my complaints. 4. Dries my eyes out terribly; worse than other glaucoma meds. 5. Makes my eyes light sensitive. 6. With the bedtime application, I usually wake up the next morning with all manner of crusty stuff in the corners of my eyes. Sometimes that gets under the lid and because of dry eye, feels like a boulder in there. It does keep my pressure low, but I've never had issues with super-high pressure, anyway."

• Pro...
• January 1, 2021

For Glaucoma, Open Angle "The first night that I used Simbrinza, I could hardly walk after about 30 minutes and shuffled off to bed. I use it in the morning at 8:45 AM and quite often have to lay down around 9:20 AM to have a sleep, which can sometimes last for two hours! I've only had the bad taste in my mouth a couple of times, but I do now struggle with dry mouth, and I must take a bottle of water with me whenever I go out. My eyes are always bloodshot now and often also very red around the eye socket. I've only just learned about the drop in blood pressure from remarks on here, so I will get checked by the doctor next week. Not looking forward to an increase in my girth as it is already much thicker than it should be! I think my long-distance sight is slightly worse but had to tell as I don't do much driving these days - and I certainly don't drive at night if I can help it."

• JPM...
• Taken for 1 to 6 months
• April 24, 2020

For Glaucoma, Open Angle "It was effective for lowering blood pressure (but I use it in conjunction with Lumigan). I take it twice daily in the AM and at bedtime. I have 4 strong side effects listed in increasing order of significance: 1. a strong bitter taste in my mouth that goes away after about an hour. 2. Very dry mouth, especially waking in the AM (I am a mouth breather). 3. Most importantly, I get EXTREMELY DROWSY after taking it in the AM. I am retired, so I can take a deep nap, but it usually lasts for 90 - 120 minutes, so this has had a major impact on my lifestyle. 4. Lower blood pressure, which I have verified with a BP cuff at home. Lower BP also manifests as light-headedness after sleeping. I have had to cut back on my blood pressure meds as a result. I am switching to an alternative."

• Geo...
• Taken for 1 to 6 months
• May 26, 2020

For Glaucoma, Open Angle "After one month's use, have decided to stop these eye drops. I wake up with a dry mouth during the night, causing regular sleep interruption. Therefore, I am already fatigued upon waking, but following the morning drop application, I feel even more tired and lethargic! The dry mouth continues during the day, and I do not leave the house without a bottle of water. My appetite has increased, and I have had rapid weight gain."

• Cup...
• Taken for 1 to 6 months
• January 19, 2020

For Intraocular Hypertension "Simbrinza lowered my eye pressure, but I noticed at times I have fallen asleep due to low energy levels. I gained a lot of weight in my mid-section, including my breasts. Mid-section weight gain is listed as a side effect."

• Chu...
• Taken for 1 to 6 months
• January 20, 2020

For Intraocular Hypertension "This is an addendum to the review I wrote on 12/15/19: The feeling of fatigue and drowsiness after applying Simbrinza is consistent and may even have gotten a bit more intense. I also discovered that this drug drops my blood pressure by 20-30 points systolic and 5-10 points diastolic for about 2-3 hours after applying the drops. Not a big problem for me, as my 'normal' blood pressure is a little on the high side. If you normally have low blood pressure, be aware of this."

• DEN...
• Taken for 1 to 6 months
• November 16, 2019

For Intraocular Hypertension "Well, what to say. It did the job bringing down my eye pressure (which was essential), but the side effects were fairly significant. Stuffy nose, dry cough, tiredness, anxiousness, night vision issues, BP changes, pinhole pupil (only for the first week), generally an unwell, foggy kind of feeling. That said, don't avoid taking it if you have a high eye pressure situation. It's worth some of the above due to its efficiency, but pharmacists and ophthalmologists should be more diligent in understanding the potential side effects and carefully monitoring patient feedback. This is NOT a side effect-free medication by any means!!!"

• MWM...
• Taken for 6 months to 1 year
• February 21, 2019

For Glaucoma, Open Angle "Medication works well in reducing pressures and doesn't have some of the side effects of other drops (skin darkening, eye color change, etc.). Sometimes it makes my eyes burn a little, sometimes a little red. The most troublesome side effect is that 2-3 hours after I instill the drops, I start to feel super fatigued. Vitals when this happens-HR 60-64, O2 sats 100, and B/P is in the low 90s over high 50s. After an hour, I will start to feel more alert and like myself-when I check my BP, it's back to 100s over 70s and then gets back in the 110s over 70s where I like it. I also take Lisinopril and was taking 40 mg/day. I've decreased that to 20 mg/day, split dose, and am staggering it every 6 hours with the Simbrinza drops, which I also use twice daily. Things seem to be stable with this approach. I tried dropping the Lisinopril altogether, but my BP was creeping up to the 130s / 90s. Luckily, this normal tension glaucoma was caught early, and I don't seem to have any peripheral vision changes yet."

• Sch...
• Taken for less than 1 month
• August 10, 2019

For Glaucoma, Open Angle "My eye pressures were higher than my ophthalmologist liked, so he prescribed Simbrinza, 1 drop in each eye am & pm. The first time I used the drop was in the evening. After a few minutes, my knees felt weak & I felt a bit lightheaded. The next morning after using Simbrinza, I felt fatigued & lightheaded. BP dropped to 94/51 & pulse was 50. I called my ophthalmologist & he said to discontinue the Simbrinza & go back to the drop that I had been previously using. Had very swift side effects after only using this drop twice."

• Bar...
• January 5, 2020

For Glaucoma, Open Angle "Hope that all comments are in not only what pharma wants to see. Simbrinza is the worst eye drop since I’m taking for a glaucoma. My life change drastically, red eyes like tomato, people asking if I smoke marijuana ,imagine and this constant pain like sand in my eyes, dry mouth and coughing. I'm going to see my doc in March only,I only hope for different drops"

• Anonymous
• Taken for 1 to 2 years
• October 11, 2017

For Glaucoma, Open Angle "I really liked that this medication did not burn, itch, sting, etc. It did not feel like something was in my eye. My only concern was that some pale yellow gooey stuff would collect in the corners of my eyes. I couldn't feel it, but I needed a Q-tip to get it out. Other than that, it was perfect."

• Ann...
• Taken for 1 to 6 months
• June 13, 2021

For Glaucoma, Open Angle "Terrible side effects with this drug. I couldn't figure out why I have overwhelming fatigue every day until I read it's one of the side effects. My eyes are so red and watery people think I've been crying all the time, and it looks horrendous. Plus, it's now difficult to drive at night due to the blurriness and halos around lights. I wake up every morning with crusty eyes. I'm going to have to get off this drug as it's made it difficult to function normally. On top of all this, it's barely lowered my eye pressure at all."

• Bar...
• Taken for 6 months to 1 year
• January 5, 2020

For Glaucoma, Open Angle "My life is a bad since I’m taking those drops, red eyes , pain like got sand in my eyes, in March I’m going to see my doc, if I’m going to be blind is better than this suffering, if is not other alternative,I’m talking about Simbrinza drops"

• Cov...
• Taken for 1 to 2 years
• January 27, 2020

For Glaucoma, Open Angle "Used several Glaucoma meds before changed to Simbrenza. First 3 weeks on this, blood red eyes, crusty eyelids, drop in blood pressure and good eye pressure. Used warm compress per Doctors recommendation and red eyes returned to normal color. Low blood pressure and crusty eyes continued. Sent to a local doctor who changed my eye meds. Used the alternative drops for one week and eyes turned blood red again. Doctor changed drops back to Simbrinza and eyes would turn white for 10 minutes and then turn red again. Discontinued Simbrinza and eyes are slowly returning to normal color with the other meds."

• Chu...
• Taken for less than 1 month
• December 15, 2019

For Intraocular Hypertension "Intraocular pressure went from mid-20s down to 14 after about 10 days of using Simbrinza. The only side effects I've noticed are blurring of vision for about 10-15 minutes after use, dry mouth and a slight bitter taste in the back of my mouth for 1-3 hours after use, and maybe feeling a little fatigued. Overall, it works well to reduce eye pressure, and side effects have been fairly minimal for me."

• Mik...
• Taken for 6 months to 1 year
• March 23, 2022

For Intraocular Hypertension "Swollen, itchy, and red lower eyelids. Crust has formed on upper and lower eyelids on the outside of the lids. Very tired all of the time. It did lower my eye pressures significantly. I use it twice each day."

• Jta...
• Taken for less than 1 month
• February 14, 2019

For Intraocular Hypertension "Post catarac surgery, developed some mild pressure, foggy vision, Dr. gave me these drops, cleared up my vision in minutes !!! I read the side effects and will be tappering off, mainly because the Dr. said it ( pressure ) would clear in time. This med was indicated to speed up the process. It worked , I was so happy, I called the Dr. office and left him a message."

• Anonymous
• Taken for 1 to 6 months
• August 28, 2013

For Glaucoma, Open Angle "Simbrinza dropped eye pressure from 34 to 14 at the 4-week check. I have experienced no side effects from this medication."

• cal...
• January 28, 2015

For Glaucoma, Open Angle "Ocular pressure down from 28 to 18 in 1 week."

• Bab...
• February 4, 2020

For Glaucoma, Open Angle "I have terrible reactions in my eyes. They go blood red, itchy, painful and the eyelids get very red as well."

• Rud...
• Taken for 1 to 6 months
• April 19, 2018

For Intraocular Hypertension "Terrible side effects. Lost all night vision, and bright lights cause glare so bad I cannot drive a car after dark. My life has been destroyed. Blurred vision and double vision."

• Bli...
• Taken for 6 months to 1 year
• August 10, 2018

For Glaucoma, Open Angle "I take this for Glaucoma. Effective at lessening ocular pressure. Makes me drowsy, so I take it at bedtime."