Brexpiprazole for Depression User Reviews (Page 4)

• Odi...
• Taken for 1 to 6 months
• June 29, 2022

Rexulti (brexpiprazole) "On 2.0 mg Rexulti, and it’s working great for my rapid cycling bipolar! Some weight gain, but if I take it before bed, I don’t notice the hunger. Starting to cook, clean, and just be a normal person again. No more angry outbursts. Have been on many antidepressants which didn’t work, or the side effects were awful (bleeding problems or breathing issues). So far, so good with this medication, but only 1 month in, I hope it keeps working!"

• Psy...
• Taken for less than 1 month
• April 10, 2024

Rexulti (brexpiprazole) "In just one week, Rexulti worked (1mg). Doctor wanted me to increase to 2mg a week after and it's been great. I feel normal. Intrusive thoughts and depression decreased. Also helped my anxiety. Very few side effects for me."

• Don...
• Taken for 1 to 2 years
• May 13, 2022

Rexulti (brexpiprazole) "I have cyclothymia, which is a mild cousin of bipolar. I was in the deepest, darkest depression, where the state police forced me to the hospital for a psych evaluation. I was suicidal. The mood swings were horrendous, and I was ruining my life and everyone's life around me. Until Rexulti tied with Lexapro. When I say life-changing and life-saving, I mean it. I'm alive because of Rexulti. Can't be without it!"

• Shi...
• Taken for less than 1 month
• June 13, 2016

Rexulti (brexpiprazole) "I started taking this a week ago, and since then, I get very little sleep. I take Ambien and Valium at night, and it has proved ineffective so far. I'm hoping this is one of those side effects that go with time. It's hard to function when you're awake every two hours."

• Roe...
• Taken for less than 1 month
• February 20, 2017

Rexulti (brexpiprazole) "I was taking this drug for depression. While on this drug a few weeks, I suffered a TIA... a small stroke. I was also on medication for high blood pressure, thyroid, cholesterol, and depression, and a pain medication. After my TIA, I am on aspirin, plus a blood thinner, nerve pain, and a higher dose of my blood pressure pill. Has anyone else had a stroke on this medication?"

• ski...
• Taken for 1 to 6 months
• July 6, 2017

Rexulti (brexpiprazole) "Rexulti has been a life changer! I'm on 1 mg. I know that's not a lot, but it's worked so well for me. Way less depressed mood than usual. I have Bipolar Type II. This was an add-on to Trileptal, and it's really been amazing for me. Would definitely recommend to others :)"

• Bob...
• Taken for less than 1 month
• November 22, 2020

Rexulti (brexpiprazole) "Took the lowest dose of Rexulti for 3 days. By day 3, I knew something was really wrong. I couldn’t remember the day (1st time in my life), felt confused, weak (I’m an athlete), and couldn’t get out of bed. Thank God I stopped, as soon as my girlfriend and I noticed the same side effects. 3 days later, I still feel lingering effects and feel obligated to warn others. Only try this as a last resort and make sure someone is with you 24/7."

• Lad...
• Taken for 2 to 5 years
• October 12, 2021

Rexulti (brexpiprazole) "It has been a great help to me since we added it to my Sertraline/Zoloft. Just to let you know, my husband told me that, “when I started taking Rexulti, he got his wife back.” What a testimony‼️"

• Anonymous
• July 18, 2024

Rexulti (brexpiprazole) "Rexulti is working for me. I feel calm. Seroquel was making me too zombie-like, very sluggish, and Abilify was too strong for me. I had trouble moving my body around. But with Rexulti, my mood is more stable than ever and able to feel much less depressed. Thank you, doctors."

• Ano...
• Taken for 1 to 6 months
• March 8, 2022

Rexulti (brexpiprazole) "I was put on Rexulti as an add-on to my Depakote for bipolar type 1 disorder. I had to come off lithium abruptly because it was affecting my sleep and causing me to have suicidal thoughts. My psychiatrist put me back on Depakote (what I had been taking prior to lithium) and then added Rexulti. It has so far been a life changer. I finally feel truly myself in a way I have not felt in years. I must have had high functioning depression for years, thinking it was my 'new normal,' but on Rexulti, I do not feel so chronically fatigued and I am actually excited about life. I can also think more coherently and clearly, and it shows in my academic performance and creativity levels. Give this medication a try if it seems nothing else is working for you because this might!!!"

• Ale...
• Taken for less than 1 month
• October 2, 2022

Rexulti (brexpiprazole) "I have psychotic depression, anxiety, and insomnia. I felt like I couldn’t survive one more day in the state I was in. I was getting four hours of sleep, and I was frozen from the anxiety and couldn’t move or speak. I was out of touch with reality. The Rexulti completely cured my anxiety, insomnia, and psychosis. I now feel like I can survive the next day, even though it’s tough because I still have depression, but my situation isn’t as desperate. I’m able to walk around, talk, and do decent in school. Since it cured two-thirds of my problems and none of the other medications I’ve tried did anything, I’m going to give Rexulti a 10/10. Very good experience. (By the way, no side effects.)"

• jen...
• Taken for 1 to 6 months
• July 18, 2018

Rexulti (brexpiprazole) "Had major anxiety for about 4 months, which led to bad depression. Doc prescribed me Rexulti because he said it would be a quick fix, and it worked for me within 4 days. I felt like my old self. My constant thoughts cleared up, I could enjoy life again. The problem is I was gaining weight like crazy. Doc also told me possible side effects down the road (muscle twitching). He now has me taking Vybriid, and it was doing good for a while, but now that I am off the Rexulti, I feel depressed again."

• Cra...
• Taken for 1 to 2 years
• May 17, 2022

Rexulti (brexpiprazole) "It works fast, and it works well. It doesn't give me the sluggish feeling or brain fog, like the others do. The only downfall is that it aggravates my tardive dyskinesia, makes it hard to sit still, hold things. But I'll take that over the alternative."

• tkm...
• Taken for 1 to 6 months
• December 13, 2018

Rexulti (brexpiprazole) "Took Latuda, did nothing for me, so the psych started me on Rexulti in mid-September. Took me off for a week in November because side effects were severe: shaking leg, irritable, restlessness. Been back on it almost 6 weeks, going from 0.5 mg to 2 mg, now feel a little okay but still have a lack of interest in things I enjoyed. I still have sadness, I'm functional but not really present. Read that some of these meds can take up to 6-8 weeks before I feel full effect. I'm on Pristiq 100 mg and 2 Clonazepam a day. Hopefully, will feel full effects shortly."

• Mer...
• Taken for 2 to 5 years
• April 7, 2021

Rexulti (brexpiprazole) "Rexulti sorted out absolutely everything as far as bipolar depression and mixed episodes go, save negative symptoms (lethargy, anhedonia), which I also take Vraylar for. Additionally, I take Depakote to avoid mania. I no longer have episodes, and my day-to-day mood is calm, hopeful, and energetic. No side effects that I've noticed. I thought it might have dampened my creativity somewhat, but then I stopped using mania as a crutch and just started working harder. My debut novel has won a pretty prominent award, so I must be doing something right. I attribute most of the heavy lifting in my cocktail to Rexulti because I had to go off it a couple of times briefly (screw-up at the pharmacy, etc.), and my mood plummeted very quickly. The difference is like night and day!"

• Bri...
• Taken for 1 to 6 months
• May 2, 2019

Rexulti (brexpiprazole) "My problems are bipolar disorder, anxiety, and depression. I was switched from Latuda 80 mg to Rexulti (which my doctor pushed on me and had samples). I also take Adderall and Prozac. I started having tremors and the biggest panic attack of my life that I ended up in the hospital. I didn’t know what was wrong with me, so I switched to an NP there. We both thought it was the Adderall making me tremor, this morning, no tremors. I went back to Ability 10 mg at night with my other usual meds! This med is not for people with non-polar disorder, it will make you worse. I’m sure it will help with depression, but they have no proven facts stating that Rexulti is for non-polar. Studies actually made it clear it made bipolar worse."

• Sul...
• Taken for less than 1 month
• August 28, 2021

Rexulti (brexpiprazole) "I have been given Abilify and Rexulti, but after many years, I did my own research on target drugs. I was ready to take my life, and it has been seven days since taking 1 mg, and I have had three good days in a row. It has been a long time. Added to 80 mg Prozac, clonazepam, and Lyrica. This is a potential game changer for my brain chemistry."

• AJ6...
• Taken for 2 to 5 years
• December 14, 2021

Rexulti (brexpiprazole) "I took Rexulti for almost 2 years for depression. I had tried many different medications, and it was the one medication that I responded to at the time. I started out on 0.5 mg and slowly increased my dosage to 2 mg. It worked for a while, but then stopped working. It also made me feel flat and sedated. My doctor added a stimulant (Adderall) to counteract the sedation, which only helped a little. We tried adding on other antidepressants with not much response. Any time I started a new antidepressant, I would feel more sedated (now I realize it was a drug interaction with the Rexulti). Finally, I decided to wean myself off of Rexulti, and the fog has finally lifted. I realize a lot of my fatigue that I was attributing to my depression was actually the Rexulti. I feel like I lost 2 years of my life! And I feel like I made a lot of poor decisions on this medication. Be careful if you are taking this medication."

• Wil...
• Taken for 1 to 6 months
• December 22, 2021

Rexulti (brexpiprazole) "Bipolar disorder (type 2 with rapid cycling and mixed episodes too)... this has changed my life! And I’m the type that had many bad experiences and then just tried natural healing for a couple of years. I gave up on meds completely. But then I found out it’s the mood stabilizers that were making me sick. Rexulti works wonders for my hypomania! Don’t give up to all those reading this. ❤️ I am also on escitalopram for depression and anxiety."

• Mic...
• Taken for 1 to 6 months
• November 5, 2021

Rexulti (brexpiprazole) "Reading the reviews on this site was part of my decision-making process in starting Rexulti for a stubborn depressive episode (I have bipolar), so I wanted to come back and leave a review myself. It's been 30 days of .5. My depressive symptoms went away after five days on Rexulti. I was afraid of akathisia because I had it really bad on Latuda, but that dreaded side effect has been minimal to none, thankfully! The first two weeks on Rexulti at .5, I did experience agitation for a few hours after taking my pill each day. However, that has mostly subsided. I am very pleased with this dose. I'm not going to increase it because I think (know) I would get akathisia and mania. Now I'm on gabapentin, Rexulti, clonazepam as needed, and ketamine infusions every few months. Keep the faith, folks. We can do this!"

• Pap...
• October 13, 2017

Rexulti (brexpiprazole) "I am on week 4 of Rexulti. I have to say it has gotten me up and on my feet. Unfortunately, it has made my anxiety so bad I feel like I am standing on the edge of a cliff trying to decide which way to turn to stop the discomfort. I have chest pain and just a general unease. No way to relax, so I will be stopping this medication as of today."

• Anonymous
• April 16, 2021

Rexulti (brexpiprazole) "After just 10 days, I am beginning to feel more like my old self. I’m laughing more and have a more positive attitude. I have moments of joy. The only downfall is that I am really hungry, especially at night. I have RA, so it’s sometimes hard with the joint pain to exercise, but I have been making sure that I get some cardio every day, even if it’s only 10 minutes. I hope this med continues to work as I love having feelings again."

• Pam...
• Taken for 1 to 6 months
• July 4, 2016

Rexulti (brexpiprazole) "When my psychiatrist finally put me on 1 mg of Rexulti, it was a lifesaver. My latest depressive episode seemed intractable until then, but a major drawback has been sleep interruption, often as early as 3 a.m. My mind races, and it's often more fun to get up than to stay in bed. I rarely sleep beyond 6 a.m., no matter how late I go to sleep. My much-valued afternoon naps have also become infrequent too. I also take Pamelor 75 mg per day and Seroquel 75 mg per day. The doctor said that I'd have to come off the Seroquel since it's the same drug family as the Rexulti. Well, I've decided to get off the Rexulti and keep my Seroquel since the Seroquel helps me sleep and wears off by morning. Rexulti is absurdly expensive."

• kma...
• Taken for less than 1 month
• March 13, 2018

Rexulti (brexpiprazole) "I only took Rexulti 2 times. My psychiatrist gave me a trial pack to try in addition to my other psych meds due to a particularly stressful time in my life that had my usual depression and anxiety far worse than 'usual.' The first time I took it was in the morning, and I was so tired all of that day that I couldn't even stay awake. I also felt no different at all and have heard that there is often a difference in how you feel within hours of the first dose. The second time I took it at night, thinking that maybe I wouldn't be affected by sleepiness then. I was still so tired the next day that I couldn't stay awake. This is not normal for me. So I didn't take any more. I can only figure this was due to the med because there were no other changes that should have caused it."

• Jay...
• Taken for 2 to 5 years
• April 19, 2022

Rexulti (brexpiprazole) "I have Asperger's, OCD, ADHD, anxiety, depression, and I've been on Rexulti, Pristiq, and Seroquel for a few years now. I've tried several medications that didn't work for me, these do. Although, when first starting on these medications, I was 70 kilos. I'm now 100 kilos, but I would put that down to the medications maybe lowering my metabolism and increasing my appetite, because I wasn't eating before! So if I had none of these conditions, I'd probably be where I'm at now anyway. When I forget to take my meds one day, I feel weird in the head. It's like a physical thing, like a tingling, but bad, and I lose focus, and I get crabby. People around me ask if I've had my meds. I'm more likely to want to binge drink when I haven't had them too. But the next day, when I remember to actually take them, I have energy, yet I'm calm. I feel peaceful but not like a zombie or wanting to sleep all the time. Also, my doses are 100 mg Pristiq, 2 mg Rexulti in the morning along with thyroid pills and vitamins. I take 25 mg of Seroquel at night to calm down and sleep."