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Amitriptyline for Pain User Reviews (Page 3)

Amitriptyline has an average rating of 7.6 out of 10 from a total of 224 reviews for the off-label treatment of Pain. 71% of reviewers reported a positive experience, while 15% reported a negative experience.

Reviews for Amitriptyline

  • Anonymous
  • October 12, 2011

"I have been in chronic pain for 11 years, worsening in the last year. Finally, a pain management doctor prescribed me 25mg of amitriptyline and it worked overnight. Magically, the next day my pain was down to a completely manageable level. I have my life back thanks to this medicine. Dizziness the first day or two, dry mouth only if I stay up long after I've taken the medicine. Don't hesitate to take this medicine if you have nerve pain, it is a miracle."

10 / 10
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147 Report
  • finally...
  • Taken for less than 1 month
  • October 27, 2013

"After 10 years of chronic abdominal pain, a bunch of tests, multiple doctors telling me to take omeprazole with no relief, I am now 90% pain-free. I started taking Endep 1 week ago and have increased to 20 mg. It makes me a little sleepy, but I take it 2 hours before bed anyway. My new doc narrowed it down to overactive nerves, and she nailed it. I'm now getting a better quality of life and am happy that I have found this med. For me, it's really worked well."

10 / 10
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128 Report
  • Steve...
  • February 6, 2017

"I was diagnosed with severe anterior bridging endophytis as well as facet joint arthropathy and some nuchal ossification in my cervical spine. Basically, my neck is fairly solid and I suffer intense pain shocks when lying down at night. The result was that I suffered from intense sleep deprivation and pain. I now take 10mg Amitriptyline. The result? Solid sleep every night, recovered energy levels, and the large black bags beneath my eyes have dissipated. I used to wake up a couple of times each night to urinate, but now sleep for a minimum of 8 hours and usually wake up bursting for the toilet!"

10 / 10
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96 Report

Frequently asked questions

  • wiggler
  • Taken for less than 1 month
  • October 16, 2014

"For two years I was experiencing nagging pains all over my body. Then it got worse, accompanied by disgusting headaches. Doctors couldn't find anything wrong. Nothing I took would help the pain, as they got more and more. Then recently I was diagnosed with M.E. I got to see a specialist and she told me to ask my doc about Amitriptyline. I have only just started taking it, and have noticed a big change. I feel more comfortable and have finally managed to sleep better. Two years ago, my doc had told me that my pains were due to me suffering depression, and prescribed citalopram. Now I am weaning away from that, as I know that all I will need is amitriptyline - it works!"

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  • Peter...
  • October 31, 2015

"After one year of MRI, CT scan, ultrasound exams for unexplained sharp chest pain (neuropathic, possible neuroma) I was prescribed 10 mg amitriptyline to be taken at night. After 2 months, this has brought me back to normal having failed with all other medications including tramadol. No symptoms at all now though it was necessary to persevere as it took about a month to kick in. Worth trying if you have drawn a blank with everything else..."

10 / 10
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107 Report

Are you taking this medicine?

  • Cupcak
  • Taken for 2 to 5 years
  • March 25, 2014

"I have interstitial cystitis for 15 years now. I have tried everything. Lyrica worked great for pain but too many side effects. I am back to amitriptyline. Works really well and very inexpensive versus thousands for Lyrica. I even took it during my three pregnancies. All my babies healthy. Dr. said this medicine has been around so long that he was comfortable giving it to me during pregnancy for my pain."

9 / 10
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120 Report
  • Krist...
  • Taken for less than 1 month
  • June 2, 2015

Elavil (amitriptyline) "I was prescribed this after a severe TBI and broken neck. It was supposed to help my headaches. After about a week, it turned me into a rapid cycling bipolar suicidal freak. One second I was driving singing happy, the next second I was trying to swerve in front of a semi."

1 / 10
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109 Report
  • RWBBB
  • November 13, 2014

"I was on Lyrica for several years to manage chronic referral pain in my foot from several back surgeries. Lyrica efficacy was wearing off and I was fortunate enough to change pain doctors, with the new doctor putting me on 30mg of Amitriptyline. I've been on it for about 5 weeks now and my pain level has come down substantially. I'm now sleeping much better and it's cheaper compared to Lyrica too. Only 5 weeks, but I'm loving Amitriptyline."

10 / 10
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114 Report
  • trishK
  • August 30, 2007

Endep (amitriptyline) "I have been taking Endep for about 20 years for pain and to help me sleep. I have seen many specialists and GPs over the years, and none of them warned me about chronic periodontal disease because of dry mouth. I was on 50mg per day. I had to have three teeth removed. I am now on 25mg. I have many health problems, apparently due to a seronegative autoimmune disease. I am also experiencing symptoms of headaches, vertigo, dizziness, balance problems, etc."

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  • Anonymous
  • Taken for 1 to 2 years
  • August 17, 2015

"I'm 20 years old and have both fibromyalgia and rheumatoid arthritis. I also use amitriptyline to treat my depression and my sleep. Before my rheumatologist prescribed this, I went through numerous other things which all caused me to get horrible headaches, stomach problems, and did nothing for my depression. I sleep well pretty much every night and I don't wake up feeling groggy. I don't have as many 'bad body days' anymore, and I feel way better emotionally."

10 / 10
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107 Report
  • susieoq
  • October 18, 2013

Endep (amitriptyline) "I have fibromyalgia and take Tramadol 150mg daily. Recently had a flare of trigeminal neuralgia and widespread neuropathic pain, and Tramadol was not working for this. Doctor put me back onto Endep, which I had given up previously as the side effects were very strong. Am now on only 5mg at 7 pm and find sleep and pain relief much better. Still feel hungover in the morning."

5 / 10
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123 Report
  • Sue
  • Taken for 10 years or more
  • August 25, 2018

"I was put on 20mg daily for chronic fatigue syndrome/fibromyalgia that I had suffered with for 15 years. I didn't believe it would work but 3 days later I felt unbelievably better. No side effects and 13 years later 10mg daily keeps my symptoms away. It was a life-giving medication for me and no obvious side effects."

10 / 10
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78 Report
  • Shelley...
  • Taken for 1 to 6 months
  • October 2, 2015

"I lost my hand in a car accident about 3 years ago. I got RSD because of that. Nothing truly helped my pain until I got on Amitriptyline. With chronic pain, it takes all your energy, but Amitriptyline helped me get my life back. I still have very bad days, but I'm able to clean again and play with my kids. Thanks to Amitriptyline, I love life again."

10 / 10
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105 Report
  • Anonymous
  • March 13, 2008

Elavil (amitriptyline) "I have chronic pain due to neck and head pain. I have been taking Elavil for 5 years, 75mg a night. It doesn't help with the pain, but I am able to sleep past the pain. If you have issues sleeping for whatever reason, give it a try. I can sleep most of the night, and I do not have a hangover the next morning."

9 / 10
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166 Report
  • Shael...
  • Taken for 10 years or more
  • March 2, 2015

"I've suffered with chronic back and neck pain, fibromyalgia, debilitating chronic migraines, and insomnia for 20 years. For ten of the last 13, I took 150mg amitriptyline with an opiate painkiller and had my pain and migraines under control and quality of life. Three years ago, my doctor had to retire due to heart problems. I have a new pain management specialist, but they only have me on 25mg amitriptyline and have me taking Neurontin instead. I've had horrifying insomnia ever since. Now I also have terrible neuropathy and paresthesia, and also interstitial cystitis, IBS, and have no quality of life anymore. But now because of all your comments, I have the courage to tell my doctor I want my dosage raised because I know what works for me. Thank you all!"

8 / 10
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107 Report
  • Bowsie...
  • Taken for less than 1 month
  • July 10, 2015

"Been on amitriptyline for 2 weeks for nerve pain following MRI scan, which revealed a soft disc touching main nerve. It has reduced discomfort from a 9 to a 3 most days. I take 2x10 mg at night and other than some grogginess the first 3-4 days, I sleep well on it too."

8 / 10
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103 Report
  • Nlil
  • Taken for less than 1 month
  • July 3, 2019

Elavil (amitriptyline) "Was prescribed a low doses for my IBS related pain. It did help my stomach but suffered badly with the side effects. Would take at night before bed but in the the daytime I’d experience shakes, anxiety, had severe trouble focussing and could barely string sentences together so stopped taking it two days ago. Still suffering bad shakes and difficulty concentrating. Be very careful with it."

2 / 10
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66 Report
  • Hkfyg...
  • August 10, 2016

Endep (amitriptyline) "I've been taking 10mg Endep for 2 weeks for bladder pain. I may have a mild case of interstitial cystitis, but I haven't been officially diagnosed yet. I have found it has worked really well with the pain. I went from being in pain all the time to only a couple of times, and it's been manageable. I have dry mouth and an increased appetite from Endep, but the worst side effect is constant drowsiness and a general feeling of being drugged up."

8 / 10
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90 Report
  • Anonymous
  • Taken for 1 to 2 years
  • November 12, 2016

"I was prescribed 10mg amitriptyline for Endometriosis - for cramps I was getting that would radiate up my back. Coupled with surgery, amitriptyline has been life-changing for me. I still have to take it around 7 pm so I don't feel too groggy in the morning, but I would rather have a good night's sleep and feel a bit tired in the morning than stay up all night in pain."

9 / 10
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87 Report
  • momsp...
  • Taken for 1 to 6 months
  • September 27, 2015

"Chronic severe pain from fibromyalgia, crowns, degenerative disease, arthritis and more. Just went to see a new psychiatrist and he prescribed 50mg nightly for depression and anxiety. I am almost pain-free. I can't believe all the docs I've had over the years never thought of this. It is definitely worth talking to your doctor about; it is truly a godsend!"

10 / 10
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96 Report
  • amazin
  • Taken for 1 to 6 months
  • July 9, 2015

"I was put on a very low dose for unexplained right upper quadrant pain. I cannot believe the difference this has made. Not only for the pain, but I was also starting to go into depression because they cannot figure out what is causing my pain. After being hospitalized, my gastroenterologist recommended I try it along with getting into pain management. I very rarely have to take a pain pill. I actually went two weeks without a pain pill. I am very pleased with my results."

10 / 10
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  • Smurf
  • November 4, 2015

"Have been suffering nerve damage pain in my leg after having three slipped discs for more than 1.5 years and tried a lot of pain relief tablets but didn't like the side effects from them. Plus, I still had the pain. My doctor prescribed me these. I must admit I really didn't think they would be any good, but I was surprised from the moment I took the first tablet. The pain had greatly decreased, so after a week, I started to take two every evening after dinner, and I hardly recognize myself. Pain-free. And the only side effect is feeling a bit sleepy, hence taking them in the evening."

10 / 10
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93 Report
  • KYGrl
  • May 6, 2016

Elavil (amitriptyline) "Have been taking for over 1 week now and after have all over fibromyalgia pain as well as night sweats, I am sleeping much better and my pain is 1/2 what it was. I was told to give it 60 days to really work but I felt better after one day."

8 / 10
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89 Report
  • Jan
  • August 19, 2016

"I have had neuropathy in my feet for over 15 years. I take 10mg a day and my feet do not bother me. Without the drug, I get a pins-and-needles or pain feeling in my feet. The neuropathy preceded a diabetes diagnosis by about 10 years. It is one of my meds that I can feel if I forget to take it. To date, I don't think I have seen a side effect."

10 / 10
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86 Report
  • Wilma
  • Taken for less than 1 month
  • December 9, 2016

"Sleepy like a baby! Two days into taking it for my endometriosis pain. Doc said to start with 10mg at first which does seem to knock me out. I take Citalopram too, but this is for that midnight pain and excruciating pain in the early hours. It's swings and roundabouts as each person reacts so differently to drugs. This for me is a 10 out of 10."

10 / 10
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83 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.