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Adapalene topical for Acne User Reviews (Page 3)

Brand names: Differin, Plixda

Adapalene topical has an average rating of 6.3 out of 10 from a total of 482 reviews for the treatment of Acne. 56% of reviewers reported a positive experience, while 32% reported a negative experience.

Reviews for Adapalene topical

  • maria
  • July 18, 2019

Differin (adapalene) "I literally never leave reviews for stuff but I had to for this. It changed my life, I am significantly happier and more confident since using this product. I had cystic acne like I had never experienced before. It was HORRIBLE- my face was extremely oily and covered in deep red blemishes. Experiencing this in college was honestly making me depressed. My friend recommended differin & at first I was hesitant but decided it couldn’t get much worse. Within the first week I noticed a change in the overall quality of my skin. While the acne had of course not suddenly disappeared, my face was significantly less oily and appeared brighter overall. After a month I’d say my acne had decreased by about 50% After three months on Differin I’d say my cystic acne was about 80% gone. After five months on Differin, I genuinely do not have acne anymore. Even when I get the occasional pimple it comes to a head within a day and quickly disappears.It changed my life!"

10 / 10
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25 Report
  • Doggyd
  • Taken for 1 to 6 months
  • April 13, 2013

Differin (adapalene) "When I first started using Differin my skin was really red and peels, for several days. After that it started to look better a lot but then out of nowhere it started to break more especially cystic acne on my face and my skin is really hot to the touch and painful. I hope it's just that it gets worse before it gets better."

7 / 10
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46 Report
  • Bex
  • August 2, 2015

Differin (adapalene) "I started using differin in February after dealing with horrible acne my last semester of college. I think it was stress related, because I've always had pretty great skin up until then. I went to my dermatologist and he prescribed me differin and antibiotics. All I can say is there is hope!! It took me 12 whole weeks to have skin I was comfortable with, but it really does work. My skin was horrible at first when I began using it, the purge as people like to call it, and I really didn't think there was going to be a light at the end of the tunnel. But seriously week 12 hit and it was night and day. I still use it every night with some days off in between but now I am actually comfortable in my skin w/ only the occasional zit"

9 / 10
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38 Report

Frequently asked questions

  • Jo04
  • March 14, 2017

Differin (adapalene) "I've tried several over the counter Acne medications and washes, home made applications and NOTHING seemed to work. I saw a commercial on Differin Gel and literally told myself, " sure, another acne med that claims to be effective " I figured, I might as well give it try considering I was beginning to accept my terrible acne. I saw results in a week or so and so did my family n friends. I am almost 2 months in and my face is practically clear, even the dark acne scars vanished. I highly recommend Differin Gel to Everyone that is suffering from mild to severe acne, I promise!! I always apply the gel after washing my face in the evening, applying the gel all over my face and jaw bone. Good luck!"

9 / 10
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33 Report
  • singer
  • Taken for 1 to 6 months
  • August 4, 2013

"I am so lucky to have discovered this medication. It has really changed my life. I am no longer afraid to let people see my face with/without makeup. This is the first time that I have felt comfortable with my skin in 10 years! If you are just starting to use this medication be patient. I did not see great results until well into the 3rd month of using it. I also found it's important to only use a small thin layer otherwise your initial breakouts will be worse. Good luck!"

10 / 10
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44 Report

Are you taking this medicine?

  • Thyro...
  • Taken for less than 1 month
  • March 7, 2017

Differin (adapalene) "I've always suffered with acne throughout my teenage years & adult life. I have PCOS & I had a full thyroidectomy due to thyroid cancer last year. I'm now 38. My hormones went crazy after surgery. I was breaking out terribly. I've tried every over the counter & natural treatment you could imagine. Nothing worked. I saw the commercial & was of course skeptical. I picked it up at target & started using it during my usual breakout time (week before my period) within a week it was cleared up! My acne scars are lighter as well. People at work are actually saying how good my skin looks! I wish I would've tried sooner. I use a very thin layer in common breakout areas. I also moisturize with coconut oil. Fantastic product!"

10 / 10
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32 Report
  • Sad
  • Taken for 1 to 6 months
  • January 27, 2020

Differin (adapalene) "I had like a few breakout so went to dermatologist for medicine and they told me to use differin gel. I guess it works for some and not for all. Because I started with 2-4 pimples and then used the differin and now I have full blown acne. Like all over my face I used it consistently for 6 months. Never stopped until I realize it wasn’t working all it did was give me more acne and I hate my face and regret using this product. It said I would see difference In 12 weeks and no more acne but I saw a difference alright...... made my face horrible. So.. happy it works for some people I guess."

1 / 10
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22 Report
  • Tiina
  • April 3, 2017

Differin (adapalene) "I have been using this gel for about 2 weeks now and have had nothing but positive results. I'm not exaggerating when I say this starting working on my skin immediately. I have been going through bad cystic acne breakouts and hormonal acne for the past two years now. Since I started using the differin, my breakouts are minimal with only one or two pimples but nothing like before. I was breaking out with 3-5 new pimples daily and the differin stopped that from happening immediately. I have extremely oily skin so the differin did not dry out my skin. I have also changed my face cleansing products and also changed my foundation at the same time. I would highly recommend this product for anyone who is at their wits end with adult acne."

10 / 10
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31 Report
  • Anonymous
  • October 17, 2015

Differin (adapalene) "I've used this product for 12 weeks now my comedone acne completely cleared after 8 weeks of use. Broke out a lot in the first 8 weeks but once I reached 8 weeks and onwards my skin has drastically changed. Would definitely recommend this for comedone acne and do try and persevere as it take at least 8 weeks to work."

10 / 10
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35 Report
  • acne
  • April 29, 2013

"I started using adapalene gel a week ago and for the first few days I broke out in loads of white heads! However I continued applying it every night before bed and within days I can already see a huge improvement!"

8 / 10
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41 Report
  • steph
  • Taken for 1 to 6 months
  • July 15, 2021

Differin (adapalene) "I've just passed the 2 month mark after having my doctor prescribe it to me. I've always used benzoyl peroxide, which has always worked for me, but I told my doc I didn't want to put something on my face every single night for the rest of my life. She prescribed Differin. She said I had to wait at least a month to see improvements, as purging is normal. 2 months later and I'm still purging. I've gotten painful acne in places I didn't have it before, and I'm overall very unhappy with the results. The prescription says it may take 1-3 months to see results, so I will continue for another month, but I don't think it'll make a difference. Would not recommend."

1 / 10
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15 Report
  • nik
  • Taken for 1 to 6 months
  • December 30, 2020

Differin (adapalene) "Hello I was excited to start this product. I knew I was going to have face purge. However it has been over 2 months and my face is really red and has so much acne. My face is worse than when I started. I don't want to give up but it is making it so much worse and I feel so ugly - disappointed."

2 / 10
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17 Report
  • JJLov...
  • November 18, 2012

"I am like completely happy! I have been struggling with acne since age 11 and am now 15! When I started using adapalene I broke out so bad I almost gave up on it but after 4 weeks my skin started clearing up tremendously! So please don't give up if something like this happens to you with this medication! Also yes there will be burning and possibly dry red thin rashes around your lips or maybe even a fever blister. Also you may feel dryness in the corners of your eyes and below your eyes and the best way to prevent some of that is to use a moisturizer but not with the medicine on but during the day when its all off. Hope this helps."

10 / 10
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42 Report
  • Anonymous
  • July 25, 2017

Differin (adapalene) "Well I've only been using this face med for a few days and my skin burns and is super dry!!! I put it on at night go to bed and wash my face in the am and apply makeup but I can't wear makeup because as soon as I apply it my face burns very bad. What do I do? Had Anyone experienced this"

1 / 10
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28 Report
  • Lila
  • Taken for 1 to 6 months
  • December 13, 2020

Differin (adapalene) "Was on DIfferin for 3 months and it never gets better. I started with 2 acnes on my chin and now I had it on my forehead, cheeks & chin. Everyday felt like nightmare & I had major breakdowns here and there. I had high hopes for this product, but I guess it failed me."

1 / 10
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17 Report
  • Anonymous
  • Taken for less than 1 month
  • August 19, 2020

Differin (adapalene) "I’m too old for this. I had some hormonal acne which didn’t surprise me since my skin is sensitive and acne prone. My dermatologist friend suggested Differin. What an awful experience. My skin looked worse even after 3 weeks that I had to stop using it. I had a lot of large cystic acne like a teenager, horribly embarrassing. Stopped it cold turkey and went back to 2% benzoyl peroxide and they went away in a week. Never again."

1 / 10
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18 Report
  • megsie
  • June 24, 2016

Differin (adapalene) "I've always had acne, ever since puberty started!! I broke out really badly at the start of this year probably because I went on a "TRY EVERYTHING" rampage and destroyed my own skin:( but yea it was one of the lowest points for me in terms of my self-esteem and confidence. I really hated looking at myself and I was so depressed. Anyway I was prescribed Differin by my dermatologist. Alas, after many painful months of breaking out, my skin slowly but surely cleared up. I would say, the initial months were VERY TOUGH but don't give up! BE PATIENT and you will see your skin transform! Give if at least 3 months"

10 / 10
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31 Report
  • mary
  • September 25, 2016

Differin (adapalene) "Struggled with acne for years, and this has honestly been a miracle worker. I've tried many different treatments (different strengths of benzoyl peroxide, oxytetracycline and limecycline) and I decided to use Differin before trying BC or accutane, and I'm so glad I did! The first week was tough, because my skin peeled rather a lot and felt extremely dry. However, I didn't experience any "purging", and the dryness was easily solved with a light moisturiser. After about 2 weeks, my skin was significantly clearer, and was no where near as dry as before. The gel has been the best treatment I've used by far, and I strongly encourage you to persevere with it as it's a game changer! My skin is now really clear and I have so much more confidence!"

10 / 10
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30 Report
  • Loopy...
  • October 16, 2016

Differin (adapalene) "This cream has been amazing for me. At first I wasn't seeing anything good except more spots, and sore skin. My boyfriend said why am I using cream to make me look worse. But I knew you had to stick at it. I got frustrated so I applied peroxide as well which was great to rid the spots fast but meant my skin all flaked off. That was horible at the time but got rid of every scar and blemish. Like a chemical peel I guess. Then 2 months in I really noticed the difference. Now about 4 months in and for about 2 months now I have had skin I had wished for for years. Clear, and no marks and can leave without make up. I honestly wish this was over the counter and don't get why it isn't because it would help so many more people who dont go to the gp"

10 / 10
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29 Report
  • Whitls
  • April 5, 2017

Differin (adapalene) "I will be 30 in 3 months and my skin is worse then it was when I was 16! What the hell! I find it interesting that everyone who really enjoyed this product, properly used this product. I was prescribed Differin when I was in my teens and it worked wonders! Now thats its OTC, I recently started using it again. I am at the 4 week point, so yes my face is breaking out. I remember when I first used it years ago the same thing happened and with patience my skin cleared up. I have already noticed a difference in my cheeks which seem to not be breaking out as bad. I am patiently waiting for this period of breakouts to come and go, so I can see those great results once more. I used Differin as a teen and loved it."

10 / 10
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28 Report
  • Mikei...
  • August 30, 2013

Differin (adapalene) "I had clear skin all the way up to junior year. I became stressed out due to the work load and decided to buy products that contained chemicals such as benzoyl peroxide and salicylic acid. I even purchased a system, but I believe that it dried out my skin and produced an oil flare up. My acne was considerably worse after 30 days. I got cystic pimples. I finally convinced my parents to seek me a dermatologist. I was prescribed Differin lotion (0.3% adapalene) along with minocycline 100mg, twice a day. I wash my face now with Purpose gentle cleansing car. The first week I only used Differin because my insurance had not cleared Minocycline yet. I saw significant improvement. Almost my 3rd month and breakouts have ceased."

9 / 10
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37 Report
  • Anonymous
  • January 14, 2016

Differin (adapalene) "Absolutely amazing! Since I have used this medicine my face has cleared up in less than a month! I had a lot of bumps on my forehead and pimples and my face including cheeks. I also feel that it is helping with my acne scars. I really hoped this helped and that more people can live with clear skin:)"

10 / 10
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31 Report
  • Grisa...
  • Taken for 2 to 5 years
  • February 28, 2017

Differin (adapalene) "I've had acne when I was a teenager, it cleared up during my 20s then came back - with a vengeance - when I was 33. Differin gel and cream has been the BEST stuff I've used and I have used A LOT of different lotions and potions which have cost me a fortune over the years. I'm now 39 and still suffer breakouts but u keep a tube handy for them and it clears them up in a couple of days. I would say to ONLY put it on the papule or pustule and not on any clear skin around them. That's when it will make your skin flake and peel off! If you use on the spots ONLY it will work just fine. I'm also a beauty therapist and I recommend that some of my clients see their GP for it."

10 / 10
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27 Report
  • Aryan...
  • Taken for 1 to 6 months
  • February 3, 2021

Differin (adapalene) "So I had high hopes for this product. Not only because I had exhausted most topical solutions for my acne but because I had seen some great reviews online. My acne was mainly on my cheeks and some spots here and there on my forehead and chin. I never really experienced cystic acne until I started using this product, 3 months in and the purging hadn't stopped. I thought I'd give it more time, 4 months in the acne is cystic and has shifted to my forehead. My right cheek is mostly clear but I have acne on my left cheek. I'm 1 week away from 5 months and my skin feels greasy, I'm getting blackheads on my forehead not to mention I now have pitted scars and hyper pigmentation from the on going purge. I'm contemplating whether I should continue with this product till month 6 or pack it in and start on trying to clear my HPI and scarring. Right now I'm in the process of making my own coconut kefir so I can heal my gut using probiotic rich foods. I honestly feel like I'm at my wit's end."

1 / 10
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15 Report
  • Jennyv
  • December 19, 2008

Differin (adapalene) "My acne became worst within the first 2 weeks of using Differin, then all of a sudden it began to get better. The improvements must have happened at night because I would get excited in the mornings when I washed my face. I have to strongly agree with the person who posted before me. DO NOT GET YOUR EYEBROWS WAXED while using this product. My skin was ripped off and immediately turned red. A day or so later it left this large UGLY scar under my eyebrows. About a week later it peeled and was fine, but who wants to go through that."

9 / 10
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47 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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