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Epiduo User Reviews & Ratings (Page 2)

Epiduo has an average rating of 7.3 out of 10 from a total of 725 reviews on Drugs.com. 65% of reviewers reported a positive experience, while 17% reported a negative experience.

Reviews for Epiduo

Commonly mentioned side effects
  • Ang...
  • Taken for 1 to 6 months
  • May 11, 2021

For Acne "I started Epiduo gel on February 1, 2021, and am still on it currently. I went in with a pea-sized amount but used it every day since the start. My skin got red and dry in the first and second week, but the side effects quickly faded. However, I am not sure if it is the purge, but I broke out/purged in the fifth week. They were not huge cystic pimples but rather small pimples with pus and many closed comedones. I was helpless with the closed comedones because there is really nothing much to do about it, and it makes my skin feel so bumpy. Through these, I still stuck to applying Epiduo gel every night, and I swapped to a gentler moisturizer from CeraVe. I think what’s really important is using a gentle cleanser and moisturizer, not picking on the pimples, and hydrating and, last but not least, letting the time pass!!"

7 / 10
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25 Report
  • Kay...
  • Taken for 1 to 6 months
  • November 10, 2019

For Acne "Back in 2016, I had severe acne. It was so painful, and it covered my entire face. I tried everything, and after a year, my face worsened. A friend recommended Epiduo, and after just a month, the acne cleared. I've been using this for years now :) Bye bye, acne. Note: too much use will cause redness. I'm using it every other day, at night only. And please just use a pea size for the entire face - just a really thin layer."

10 / 10
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31 Report
  • Sta...
  • Taken for 1 to 6 months
  • August 29, 2019

For Acne "Please do not get your eyebrows waxed or threaded whilst using this! Recently had my eyebrows waxed and ripped a whole layer of my skin off. Very painful and so inflamed, leaving me unable to leave the house."

9 / 10
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34 Report
  • Aye...
  • Taken for 1 to 6 months
  • July 16, 2023

For Acne "I have had cystic acne for 12 years, and it is honestly one of the most painful, confidence-wrecking conditions. I have tried so many prescription creams, including adapalene on its own, but nothing has ever given me perfect skin. This cream is absolutely incredible. I’m just two weeks in, my skin is completely clear, I have post-inflammatory hyperpigmentation and now a month in, it’s incredible. I cry when I look at my skin because I never thought it would be smooth. I never thought I could cure my acne. I still get one or two tiny pimples, but I use the cream once a night, and by day two, it’s flat and gone. My skin is used to retinoids, as I used adapalene with no joy for two years. Swapping to Epiduo has been incredible. The combination of adapalene and benzoyl peroxide did give me slight dryness, but now my skin GLOWS. Miracle cream for severe cystic acne, and I will never ever stop using it now!"

10 / 10
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12 Report
  • Tea...
  • Taken for 1 to 6 months
  • November 11, 2019

For Acne "Was concerned when I first started to use Epiduo because my face started to break out even more. I stayed consistent and by week 3, I started to see really great results. Lots of burning when I first started. Like I would get literally burns around my mouth, eyes, and sensitive parts of my face, but after staying consistent and not rubbing so hard when washing my face, the burns stopped."

9 / 10
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27 Report

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  • got...
  • Taken for less than 1 month
  • October 8, 2014

For Acne "I've had acne for 10 years, and this is the only thing that has worked. I've been on a few other prescription medications, and they didn't have the same results. My skin does get dry, but I just use a non-comedogenic moisturizer (Cetaphil), and it helps immensely. My skin is clear, and it feels smooth. Don't let the other reviews about redness and irritation scare you off. You should just reduce your usage to every other day instead of every day, and it still works. Also, the claims that it causes more acne are unlikely since it has TWO acne-killing medicines in it. If you use it correctly and how it best fits your needs, I promise you won't be let down."

9 / 10
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  • emi...
  • Taken for 1 to 6 months
  • September 7, 2015

For Acne "I'm just gonna get right to the point by saying that I'm just about to hit my 12 week mark on Epiduo, and it has completely cleared up my acne!! From 1-4 weeks, my acne kept getting worse. From 4-6 weeks, it was just kinda stuck in one place where it didn't really get worse but never got better. From 6-9 weeks, it slowly started to get better, but I was still waking up every day with a new pimple. Then from 9-12 weeks, I REALLY started noticing a difference. Pimples stopped occurring every day (with the exception of a couple because my period was starting). So for everyone using this product, just give it time to work! And for anyone wondering, I use Cetaphil Derma-Control Foam Wash in the morning and night but only apply Epiduo at night (waiting 30 min after to apply the moisturizer). Also, I really recommend getting the epi-tracker app to track your progress. SO GOOD LUCK EVERYONE."

10 / 10
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43 Report
  • Epi...
  • May 2, 2014

For Acne "I've been on Epiduo for quite some time now. I went from using it every day to once a week! It's super effective, and I LOVE it! I recommend Epiduo to everyone with acne. I used to have a face full of acne, now I only have like one or two pimples. Epiduo is amazing!"

10 / 10
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  • Epi...
  • Taken for less than 1 month
  • August 12, 2014

For Acne "A couple of days ago, I was prescribed Epiduo. I didn't have really bad acne, but I had just enough where I didn't like my face. I've been trying Epiduo for a couple of days now, and I have already seen improvements in my face."

8 / 10
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46 Report
  • bba...
  • January 19, 2021

For Acne "I have been using Epiduo for 17 nights. Initially, it made my skin super smooth, with no breakouts, burning, or purging. However, after about a week, it became extremely painful, and my skin burned like crazy. Dry patches appeared around my eyes and mouth. I moisturized with Bria Organic Balm, and it cleared up within 2-4 days. One thing I will say for those who experience dry patches, burning, and peeling is to protect them while they heal. Put on a thin layer of thick moisturizer, massage it into the affected area, and cover it with Vaseline. Vaseline acts as a barrier, and therefore the benzoyl peroxide won’t travel to the affected areas. Vaseline is your friend in the fight against burning. Also, a handheld fan - or really any fan - is the best to just point at your face and sleep with! When they say a pea-sized amount, they mean it. You want as little as possible, but don’t worry, it will still work."

8 / 10
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  • Niq...
  • May 25, 2015

For Acne "I never had acne until I hit 19. I let it go for a while, thinking it would go away. Then I tried a whole variety of home remedies, over-the-counter treatments, supplements, and stopped wearing makeup, and NOTHING was working. I went to my GP, fed up and with low self-esteem, and she prescribed me Epiduo! At first, I was skeptical, after all, it was just a cream, but then I began to use it. For the first month, I had terrible irritation and burning, my skin would crack and peel, but I was so determined to clear my skin I pushed on. Around the 50-day mark, a miracle happened! Not 1 pimple! And I haven't had one since! My skin is just amazing now, people are complimenting me all the time about it, and I feel fantastic!"

10 / 10
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  • Anonymous
  • September 27, 2009

For Acne "I started using this medicine about a week ago, and I've already noticed significant changes in my skin. Prior to use, I had a very bad breakout of acne all over my face: small bumps and big ones. Now, I have very, very few bumps, and also the scars left behind from old bumps are also beginning to clear up and lighten my complexion for a more even tone. The only downfall is the stinging that occurs sometimes, along with minimal peeling. But other than that, it gets the job done, and I'm pleased with what I'm seeing thus far. Hopefully, it continues to eventually make me acne-free."

9 / 10
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  • Bro...
  • Taken for 1 to 6 months
  • May 22, 2019

For Acne "First of all, after reading the other reviews, I see that a lot of people stop using this because of the redness, dryness, and burning it causes. If you stick with it for 2 weeks, the burning and redness subsides! You cannot give up on this product (or any other acne product) after only using it for a week. With that being said, I too experienced the irritation and dryness in the few weeks. I honestly love how much it makes your skin peel because it allows your past acne scars to fade! Yes, the dryness is annoying (especially if you are a makeup wearer)... but you have to look at the bright side, it fades your scars! I’ve been using this for 1 month and have seen drastic changes already in my skin's appearance and texture. I alternate between using Epiduo and Tretinoin at night. I had already been on Tretinoin for 3 months before adding Epiduo to my routine, so I did not experience a purge like other people do."

10 / 10
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29 Report
  • Mar...
  • January 15, 2021

For Acne "I started using Epiduo in November 2019, and back then my skin wasn’t very good. I had mild to moderate acne at the time and started using Epiduo once, maybe twice a day. The first month was horrible, and my skin started to get way worse. My breakouts were way worse than when I started. I didn’t have a burning sensation, however, my face started peeling like crazy. I had to use moisturizer all the time, and makeup would never cover it up. At the 2-3 month mark, my skin started getting slightly better with pretty bad scarring. However, when I reached the 6-month mark of this medication, I was VERY pleased with the results. It got rid of my scarring drastically, and my breakouts now are a lot better than they were before. I still have acne here and there, but nothing compared to what it was before. It doesn’t work for everybody, but it worked miracles on my skin."

9 / 10
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  • m97...
  • Taken for 2 to 5 years
  • May 21, 2017

For Acne "I was prescribed Epiduo right before my senior year of high school, and I have now just finished my second year of college. For all of you reading reviews, don't believe any reviewer who has used this medication for less than 6 months. My dermatologist told me to use this every night on my whole face. I didn't have red pimples, but I had comodogenic acne-very bumpy, textured skin that drove me crazy. It took one full year to work, but it made my skin absolutely perfect-glowing, clear, tiny pores, everything I could ever have wanted. Flash forward to now, and I have moved up to Epiduo Forte because my skin is used to the regular Epiduo. There is no doubt about it. This works. But you have to stick out the awful part."

10 / 10
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31 Report
  • sam...
  • Taken for 6 months to 1 year
  • March 9, 2017

For Acne "Honestly, don't give up on this cream. I had acne since I was 13 years old, trying all sorts to clear my skin, but nothing worked, so I just dealt with it every day, covering myself in makeup. I'm now 21, and my skin is as clear as it has ever been. I started to use this cream 6 months ago, but after 2 weeks on it, I broke out in spots even more, and my skin started to peel to the point I couldn't even touch my face because it hurt. So I gave up the cream for a few weeks, but then decided to read some reviews, and I took on the advice of what people were saying to stick to it. I went back to the doctor's, got the cream again, 3 months on, the redness/peeling stopped and my skin is clear. I no longer wear makeup and feel confident! STICK IT OUT!"

9 / 10
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  • xze...
  • June 20, 2013

For Acne "I'm 18 and have always struggled with hormonal acne. But for some reason, the past few months have been terrible. It was everywhere, and I felt so insecure. I went to the doctor, and she recommended Epiduo. Best decision ever! At first, I hated it because my skin is dry, itchy, flaky, and burns. But I finally found out how to put it on so it doesn't. Try this and see if it works: First, wash your face GENTLY with a NON-MEDICATED cleanser. Now this is the key. You have to wait for your face to completely dry between layers. Wait at least 10 minutes. So once that's dry, apply the Epiduo in a thin layer all over your face. Let dry for 15 min. Then apply a ton of moisturizer. My skin is so clear now!"

9 / 10
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44 Report
  • Por...
  • September 20, 2019

For Acne "I've had acne pretty well my whole life. However, after entering into my 20s, my adult acne got worse. I had small pimples down my jawline and cheeks. I got prescribed this medication about three months ago. You HAVE to get through the “purging stage”, things will get worse before they get better. You have to give this medication a chance before you can see results! I had extremely dry, red, burnt skin. So bad, people thought I had a sunburn. I actually stopped after using it for two weeks because of how insecure I was and the side effects of the cream. My skin peeled, I couldn’t put any makeup on. This lasted a little over a month before my skin got used to it. It will take several months for this to work! After about a month and a half, this medication made my pores smaller, my skin glowing and smooth. I’m so happy with how great my skin looks! I have people telling me how great my skin looks and asking what I’ve been using. Stick it out, it’s worth it!"

9 / 10
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23 Report
  • Anonymous
  • September 28, 2010

For Acne "I started using this medication on September 7th, 2010, and today's date is September 28th, 2010, and boy, have I noticed a big difference. The first couple of weeks, I felt like giving up because the burning and peeling were unbearable. But now my face is a lot clearer, and the burning and peeling are gone. It still has some ways to go, but it's so much better. My advice to you is to hold on and wait a little while longer because you will see awesome results once you get past that stage."

9 / 10
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50 Report
  • Meg...
  • May 2, 2017

For Acne "I posted about a month ago and feel that I should post again. It's been 46 days since I started Epiduo. My scars are still fading, my skin looks and feels tighter (in the best way), and I feel as if my pores are getting smaller. I've read people say this doesn't happen with Epiduo, but it's happened to me. I did just get 2 new pimples, but those are the first since the second week of using this med, and I just started my period. But I'll take it compared to what my skin was before! Huge tip: download the Epi-Tracker in the App Store. Take a picture every morning to track the progress and keep you committed! It tells you how many days you've been using it and lets you compare the progress. Super helpful."

9 / 10
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29 Report
  • Cam...
  • May 1, 2015

For Acne "I had horrible acne since I was 13+. I've been using Epiduo since I was 16, and I can't go without it! I'm now 18, and I've never stopped using it. It's amazing. At first, you will be very irritated, and your skin gets super dry. But give it a week or two, and you'll be fine. Your skin adapts, and after that, it's great. I don't know what I would do without it, because there have been times when I stopped using it for about a month or two, and my acne starts coming back. So I guess I'll be using this the rest of my life, lol. I get so many compliments on my skin since I've been using this product, everyone asks me what I do."

10 / 10
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37 Report
  • ann...
  • May 13, 2014

For Acne "I've had great results with this medication. I tried Differin prior to this, and it did nothing for me. This medication cleared my skin up in a week and has kept my acne at bay ever since. Only negative is that it does burn at some points (I do NOT have sensitive skin)."

9 / 10
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36 Report
  • Jaz...
  • January 27, 2015

For Acne "I have been on Epiduo for about 3 weeks, and it seems like every time I apply the gel, I turn red and breakout more. Then it's accompanied by dry, flaky skin. I think I'm going to stop the use of the Epiduo gel."

1 / 10
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68 Report
  • Anonymous
  • April 26, 2010

For Acne "Love Epiduo. I have been on every type of medication for acne. These include oral antibiotics, topical creams, and even Accutane. A year after being off Accutane, my acne was starting to get bad again. My dermatologist recommended a second course of the drug. I was very reluctant to do so, so I asked to try one more thing before starting Accutane again. I got prescribed Epiduo, and I love it. I am using it at night before I go to bed, and it is working amazingly. I actually saw results the first week of using it. I did have some dryness, but nothing I couldn't handle. I'll take dry skin over an acne breakout any day. Definitely worth trying."

9 / 10
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48 Report
  • Ale...
  • December 12, 2014

For Acne "I'm so thankful for Epiduo! It works wonders! Yes, there is the downfall of dry, flaky skin, but that can be cured with Cetaphil oil control moisturizer. Other than that, my face feels and looks amazing!"

10 / 10
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40 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.