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Acyclovir for Herpes Simplex User Reviews (Page 3)

Brand names: Zovirax, Sitavig

Acyclovir has an average rating of 7.9 out of 10 from a total of 82 reviews for the treatment of Herpes Simplex. 72% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Acyclovir

  • slduke
  • Taken for 5 to 10 years
  • October 19, 2021

"I have had this for 10 years or longer and I wanted to let people know about Acyclovir and Valacyclovir and my experience with them both. I only read one review that mentioned this and it's on the Valacyclovir side of reviews from 2019. So I was first given acyclovir 200 mg 2 pills 3 times a day which I really never needed to take that many to clear up my symptoms . I didn't want to take that many if I didn't need them and become used to them, cause we all know how an outbreak can be. Fast forward to 6-2021 I went to my dr for a check-up on all meds and we discussed trying Valcyvlovir 500mg I thought why not its newer and supposed to last longer not having to take as many pills, I was all for it. Well if its not broke dont fix it, cause I had a flare up it didn't go away not near as good as with a dose of Acyclovir capsules. So I called and told the dr I wanted the Acyclovir back the other didn't work for me. So Beware newer or stronger is not always better."

8 / 10
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  • SmittyE
  • Taken for 1 to 2 years
  • December 12, 2012

"I have been taking Acyclovir for almost 2 years now. I believe it to work because I've only had 1 outbreak in the 2 years. I was given the option to take 200mg every 4 hours. (equals 5 a day) for 5 days when an outbreak occurs or to take everyday but I have only taken for the 1 outbreak."

10 / 10
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20 Report
  • Jenny
  • Taken for less than 1 month
  • December 29, 2019

"I had a rash on my hand that my doctor thought (misdiagnosed) was the shingles. I was prescribed acyclovir and I had a severe allergic reaction. It turns out it was Dyshidrosis (pompholyx) blisters on your hands from stress. Chickenpox/shingles are viral, you do not need to take anything except pain medication. I suffered with hives all over my body the size of dinner plates, it felt like I was being burned alive. I was throwing up, lost weight and my skin/face began to show signs of jaundice. I thought I maybe fatal at one point, my skin began to thin to the point I was seeing the coloration of muscle underneath. I still have scars from it. I had these terrible hives for three months until I was given a steroid shot and montelukast. It was a terrible allergic reaction and this medication is known to cause Steven Johnsons Syndrome (SJS), google it because it is terrifying. The hives were gone in 24 hours after getting steroid shot. Do not take this medication, you could get SJS which can be the end of your life or ruin your life."

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Frequently asked questions

  • lexus
  • Taken for 1 to 6 months
  • May 4, 2016

"Unfortunately my ex-boyfriend intentionally & knowingly gave me Herpes. The first breakout was horrible, I had to go to the Emergency room. They prescribed me Acyclovir 400 mg 4x daily. It definitely works and it works fast. I had no side effects at all. I always keep it on me and I am to take 200mg 5x daily if I start to have another breakout."

10 / 10
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  • Shep
  • Taken for 10 years or more
  • September 24, 2020

"I'm 74 years old. First diagnosed 40 years ago so I've been using Zovirax and acyclovir cream a while. Both have been effective in eliminating or reducing outbreaks. Especially if applied at very first signs of oncoming event. I haven't had a cold sore in that time because I apply the cream when I feel any tingling or raised skin surface. Very little cream is needed to be effective but, several applications a day works best."

10 / 10
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Are you taking this medicine?

  • Leah
  • Taken for less than 1 month
  • March 26, 2016

"Ive been diagnosed with this about 2 maybe 3 weeks ago ...my boyfriend gave it to me i found out when he had a breakout....the night before we had sex so we both went to the er to find out whats wrong ....I have not had a break out was on the 5 pill a day thing but my body couldnt handle it so the doctor put me on the pill i time a day ....idk whats going on but now I cant pee ive been trying to pee for 14 hours...ut feels like I have to go then when I sit on the toilet nothing but a few drops come out"

4 / 10
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  • Three
  • Taken for 1 to 6 months
  • July 29, 2020

"I was diagnosed with herpes this year after getting it from my partner. I had a fairly bad first outbreak on my inner labia and just presumed it to be from shaving but I went to a sexual health clinic and got diagnosed. This medicine has been so helpful anytime I have a tingling/throbbing sensation I take it and it works wonders. I’m currently taking it at the moment and the only real side effect I have is having a headache!"

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  • bummers
  • Taken for 1 to 2 years
  • May 11, 2020

"Started taking this after an outbreak. Thought the first one was just irritation from a wax. Realized after that second time it happened that it was definitely herpes and triggered by bikini waxing. Now take this daily to suppress and have not had an outbreak since (over a year). Have found it definitely has caused me to have increased sweating at night, which is annoying, but otherwise no issues."

10 / 10
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  • cold...
  • Taken for 1 to 2 years
  • April 13, 2016

"I suddenly keep getn these horrible cold sores like I was slit with a razor outside in like half inch splits that sting so bad n a couple times I've gotten a single sore down unda that hurts n is red. I go as long as I can bare it n sometimes it goes away on its own quickly but wen It doesn't I take one of my sisters acyclovir's a day n 9times outa 10 it goes away within a few days. I now take lysine with my daily vitamins. U cant just take vitamins wen u need em u gota take em daily so wen u get sick or watever they've already built up in ur system. I skipped a few days last week n i already got 2cold sores. Abreva only works if u use it at the 1st sign of a cold sore, once the sores there it will not work n that's a big waist of money"

9 / 10
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  • happy...
  • December 29, 2010

"I've had outbreaks on my lips for over 25 years. At the age of 30 I'm told to try taking a pill at the first sign, only couldn't find a doctor to prescribe me any until AFTER I broke out so they could SEE I actually had one. Finally I found a doctor and now I take 200 mg every third night and a full 400 mg if I even think I'm getting a sore. So far so good, no outbreaks in 3 years. Love it. No side effects either!"

10 / 10
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  • Anonymous
  • October 19, 2011

"I'm 25 and I've always had cold sores in my mouth since I was 4 and it can happen with sun or eating citrus. It's only getting worse now that I have braces so my Orthodontist told me about this pill and my doctor gave it to me and I love it EXCEPT I get a headache, fatigue, dizziness and joint pain...but it's totally worth it!"

8 / 10
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  • SDRV
  • Taken for less than 1 month
  • October 25, 2015

"I started with feeling like I had a cut in my genitial area at first, was tested at urgent care for herpes (doctor said it doesn't look like herpes) he came back telling me I had herpes two days later, I was then explained I have genital herpes, went to my gyn and was told I don't have genital herpes but herpes simplex. I was prescribed this drug and have never had an outbreak on my mouth before and so far I have had three oral outbreaks while taking 400mg twice daily. Within 23 days of use....? I want to try taking 400mg in the morning and 800mg at night now because this is not helping me. Haven't had any breakouts anywhere else though. Now bf has a cold sore as well. I need more than this."

2 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • February 22, 2017

"This is the only thing that works for myself stress induced break outs (college). I use both the pills and the cream. I believe when I first started using acyclovir it was more effective and now it can take a good 4-5 days to fully heal. This is nothing in comparison to a cold sore that lasted a month without the meds though! 400mg. Free with my healthcare for the pills, the cream was $25."

9 / 10
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  • JBano
  • January 25, 2019

"When using oral and cream at onset gets rid of them fast. But remember this oral stuff really bad on the liver. If outbreaks are like a few times a year not to worry. If down in Mexico can get for a fraction of the cost then in the states."

10 / 10
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  • leach...
  • Taken for less than 1 month
  • July 17, 2016

"Can anybody tell me how to deal with a red, swollen eye with blurred vision 5 days after stopping using Zovirax eye ointment. Could anybody also tell me how to stop falling asleep while taking aciclovir tablets. I find this drug debilitating and will go to see an optician about my virus."

1 / 10
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  • GetYo...
  • Taken for 1 to 6 months
  • February 2, 2022

"Diagnosed with HSV2 11 years ago. Never received information of tablets I could take. Searched for a natural remedy. An active gym enthusiast and going through the stresses in life, I had outbreaks nearly every other months that lasted weeks. Tea tree oil stung like anything, L-Lysine sometimes worked, but I'd have to take 6000mg+ everyday which made me tired. Hot baths did nothing either. Smoking and drinking definitely assisted in causing outbreaks. I cut these two out as it had health benefits being in my mid-30's. Exercise of any sort resulted in outbreaks. Manscaping would cause outbreaks too. Depression was getting worse, I had no sex life and I needed to be me. Not a fan of prescribed medicine and avoided the dr's being 'manly' but I thought what the heck after seeing reviews on this site and it's saved my life. 10+ years of depression gone in an instance! 400mg once or twice per day. A lot of people have HSV2 and it could be worse. Stay positive! Time to catch up for lost time ;)"

10 / 10
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  • Anonymous
  • April 24, 2009

"I went to the doctor today and they looked in the back of my throat. There were white irritated pockets in it. There were sores on my upper lip, on my bottom lip and roof of my mouth. Of course I thought it was STREP THROAT, so the doctor gave me a strep test and it came back negative. He said it was a form of herpes. A viral canker sore infection. So he prescribed me ACYCLOVIR 200MG. I take 2 capsules 3 times a day for 5 days and it should clear it up."

7 / 10
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  • Zovir...
  • February 19, 2018

"For the last year I've been plagued with severe cold sore/herpes outbreaks around my lips, chin and nose. A never ending cycle of breakout, heal, breakout. After one day of using the cream and Acyclovir the large bump on the side of my lip flattened to the point of not noticing it. Day six and I haven't seen my face look this clear in years. One little teeny whitehead popped up last night below my lip but you can't tell its a herpes sore. It kind of seemed like a final whimper. If I could rate prior breakouts as a 10 for worst case scenario, this little guy would be a 1. And I'd even thank someone for it. One last thing, If you're insured look around for community health centers, call them and ask for a low cost pharmacy to fill your prescription. I've read online the same Zovirax cream prescription goes for $200, and Acyclovir anywhere from $80-200. I paid $100 for both. Do some research!"

10 / 10
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  • Horri...
  • Taken for 10 years or more
  • April 12, 2020

"I was prescribed this meds and it did work, years later I'm still battling with this virus, I never gave it on to anyone, anytime I feel discomfort I call my dr to send a script to the pharmacy. I have had a outbreak on different parts of my vagina and by my anus & mouth. The ones that comes by my vulvar or anus is the worst especially when I urinate I always have that cup of water to pour while I urinate so it wouldn't burn.I'm having an outbreak now I been feeling this itch & painful feeling that got me up. I took a pill about 30 min ago I can honestly tell you Im feeling the med kick in. My pill is 500mg I try to keep some on hands for times like this my dr is close."

10 / 10
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  • Infec...
  • April 4, 2017

"At 29 weeks pregnant I had a fever. Thought I was leaking amniotic fluid. Went to the hospital and misdiagnosed with a UTI. Stayed overnight with IVF and antibiotics and checked, monitored and ultrasound before discharged the following day. 24 hours later still not having felt well went back to the hospital and rechecked, water broke dilated to 2 and Dr said she didn't think of it before, but was going to test and treat me for Genital Herpes. Right after the emergency c section. "

7 / 10
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6 Report
  • Dee
  • Taken for less than 1 month
  • February 19, 2021

"I found out on Tuesday that I have herpes went to many doctors before got diagnosed with herpes started itching in 2014 didn't know what it was but can someone give me some advice on how to rid myself of it"

3 / 10
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  • Someb...
  • January 13, 2016

"I have breakouts on my nose, I used to dance and thought it would be cute to bend down, while on stage and brush there nose with mine. That turned out not so good, I wish I wasn't so nieve. I've been living with them for about 6 years and when they came out with sitavig, that's really good. I only breakout about every 2 years, when stressed or if it's really hot."

10 / 10
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  • Jeepg...
  • December 30, 2016

"I got oral herpes on my face when I was in the orange in russia. I've had it seen I was younger. I'm 22 now and deal with this. I hate it. But the medication is very effective for me. I'm currently between doctors and ran our of my pills :(.. and I have a flare up. To much stress lately. I don't know how it feels to have genital herpes but I can tell you having it on my cheeks burns like crazy. Ugh..this cream isn't doing anything either."

8 / 10
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  • Grey
  • October 31, 2020

"I think it worked okay within 3 days my breakout was gone. But I don't like that you have to take it 3 times daily for a week straight then keep taking it for prevention if you get breakouts because I forget half the time. It makes me really sick if I don't eat and I have celiac disease so if you can't eat much like I can't this isn't the right kind for you. Because it's not the right one for me and the pill itself is huge looks like a dungeon and dragon symbol"

9 / 10
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  • Parent
  • Taken for 6 months to 1 year
  • May 20, 2020

"My child came in contact on va cction and has a skin rash HSV-1 and this medicine does not work at all for her. I hate to see her so irritated I wish there was an actual cure. I used vinegar and coconut oils and it took just as long to clear as this drug.."

1 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Herpes Simplex

Symptoms and treatments

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