Epidural Steroid Injection

Medically reviewed by Drugs.com. Last updated on Apr 6, 2025.

• Care notes
• Ambulatory
• Discharge
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An epidural steroid injection (ESI) is a procedure to inject steroid medicine into the epidural space. The epidural space is between your spinal cord and vertebrae. Steroids reduce inflammation and fluid buildup in your spine that may be causing pain. You may be given pain medicine along with the steroids.

DISCHARGE INSTRUCTIONS:

Call your local emergency number (911 in the US) if:

• You have a seizure.
• You have trouble moving your legs.

Seek care immediately if:

• Blood soaks through your bandage.
• You have a fever or chills, severe back pain, and the procedure area is sensitive to the touch.
• You cannot control when you urinate or have a bowel movement.

Drugs used to treat this and similar conditions

Call your doctor if:

• You have weakness or numbness in your legs.
• Your wound is red, swollen, or draining pus.
• You have nausea or are vomiting.
• Your face or neck is red and you feel warm.
• You have more pain than you had before the procedure.
• You have swelling in your hands or feet.
• You have questions or concerns about your condition or care.

Care for your wound as directed:

You may remove the bandage before you go to bed the day of your procedure. You may take a shower, but do not take a bath for at least 24 hours.

Self-care:

• Do not drive, use machines, or do strenuous activity for 24 hours after your procedure or as directed.
• Continue other treatments as directed. Steroid injections alone will not control your pain. The injections are meant to be used with other treatments, such as physical therapy.

Follow up with your doctor as directed:

Write down your questions so you remember to ask them during your visits.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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