Mepivacaine

Generic name: mepivacaine [ me-PIV-a-kane ]
Brand names: Polocaine, Polocaine DENTAL, Polocaine-MPF, Scandonest, Carbocaine HCl, Carbocaine
Dosage form: injectable solution (1.5% preservative-free; 1%; 1% preservative-free; 2%; 2% preservative-free; 3%)
Drug class: Local injectable anesthetics

Medically reviewed by Drugs.com on Aug 3, 2023. Written by Cerner Multum.

What is mepivacaine?

Mepivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

Mepivacaine is used as a local (in only one area) anesthetic for an epidural or spinal block. It is also used as an anesthetic for dental procedures.

Mepivacaine may also be used for other purposes not listed in this medication guide.

Mepivacaine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives, itching, skin redness; nausea, vomiting, sweating, feeling hot; fast heartbeats; sneezing, difficult breathing; dizziness, fainting; swelling of your face, lips, tongue, or throat.

Tell your caregiver right away if you have:

• numbness and tingling in your mouth or lips, metallic taste in your mouth;

• ringing in your ears, blurred vision, slurred speech, headache;

• confusion, depression, severe drowsiness, feeling like you might pass out;

• slow heart rate, weak pulse, weak or shallow breathing;

• fever, neck stiffness, increased sensitivity to light;

• tremors or muscle twitching, feeling anxious or restless;

• ongoing numbness, weakness, or loss of movement in your legs or feet;

• loss of bladder or bowel control;

• loss of feeling in your lower stomach, groin, or genitals;

• painful or difficult urination; or

• fast heart rate, rapid breathing, feeling hot.

Common side effects of mepivacaine may include:

• anxiety, feeling restless or excited;

• depression, dizziness;

• tremors; or

• blurred vision, ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Spinal numbing medications can have long-lasting or permanent effects on certain body processes. Talk with your doctor about your specific risk of nerve damage from mepivacaine.

Before taking this medicine

You should not receive mepivacaine if you have ever had an allergic reaction to any type of numbing medicine.

To make sure mepivacaine is safe for you, tell your doctor if you have:

• liver or kidney disease;

• low or high blood pressure;

• heart disease or a history of stroke;

• heart rhythm disorder;

• coronary artery disease;

• epilepsy or other seizure disorder;

• a drug allergy; or

• if you regularly use any medicines (especially to treat migraine headache, depression, or mental illness).

FDA pregnancy category C. It is not known whether mepivacaine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using mepivacaine.

It is not known whether mepivacaine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is mepivacaine given?

For an epidural or spinal block, mepivacaine is injected into an area of your lower back near your spine. You will receive this injection in a hospital or surgical setting.

For a dental procedure, mepivacaine is injected into the gum area inside your mouth. You will receive this injection in a dentist's office or oral surgery setting.

Your breathing, blood pressure, oxygen levels, and other vital signs may be watched closely while you are receiving mepivacaine.

Spinal numbing medications can have long-lasting or permanent effects on certain body processes. This includes sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from mepivacaine.

Related/similar drugs

lidocaine ophthalmic, cocaine nasal, bupivacaine

What happens if I miss a dose?

Since mepivacaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.

What happens if I overdose?

Tell your caregivers right away if you think you have received too much of mepivacaine.

Overdose symptoms may include extreme drowsiness, seizure (convulsions), shallow breathing, or slow heart rate.

What should I avoid after receiving mepivacaine?

After your dental procedure, avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Mepivacaine can cause numbness for a long period of time. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.

What other drugs will affect mepivacaine?

Other drugs may interact with mepivacaine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2024 Cerner Multum, Inc. Version: 4.01.