Vilanterol use while Breastfeeding

Summary of Use during Lactation

Although no published data exist on the use of vilanterol during lactation, data from the related drug, terbutaline, indicate that very little is expected to be excreted into breastmilk.[1] Vilanterol is available only in combination products such as Breo Ellipta and Anoro Ellipta. The authors of several reviews agree that use of inhaled bronchodilators is acceptable during breastfeeding because of the low bioavailability and maternal serum levels after use.[2-4] Combination products such as Breo Ellipta and Anoro Ellipta are likely to be acceptable for similar reasons.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Formoterol, Salmeterol

References

1.

Lindberg C, Boréus LO, de Château P, et al. Transfer of terbutaline into breast milk. Eur J Respir Dis Suppl. 1984;134:87–91. [PubMed: 6586490]

2.

McDonald CF, Burdon JGW. Asthma in pregnancy and lactation. A position paper for the Thoracic Society of Australia and New Zealand. Med J Aust. 1996;165:485–8. [PubMed: 8937369]

3.

Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001;56:325–8. [PMC free article: PMC1746013] [PubMed: 11254828]

4.

Taddio A, Ito S. Drugs and breast-feeding. In, Koren G, ed. Maternal-fetal toxicology. A clinician's guide. 3rd ed. New York. Marcel Dekker. 2001:177-32.

Substance Name

Vilanterol

CAS Registry Number

503068-34-6

Drug Class

Breast Feeding

Lactation

Beta Adrenergic Agonists

Bronchodilator Agents