No information is available on the use of givinostat during breastfeeding. Because it is 96% bound to human plasma proteins, amounts in milk are likely to be very low. If a mother requires givinostat, it is not a reason to discontinue breastfeeding. Until more data become available, givinostat should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Monitor the breastfed infant for diarrhea, vomiting, bruising, excessive bleeding from cuts, and blood in the stool.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Givinostat
CAS Registry Number
497833-27-9
Drug Class
Breast Feeding
Lactation
Milk, Human
Histone Deacetylase Inhibitors
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
