Drugs containing Corticotropin: Acthar, ACTH, H.P. Acthar Gel
Corticotropin Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the clinical use of corticotropin during breastfeeding. Because it is a relatively large molecule with a molecular weight of 4541 Da, it is unlikely to appear in breastmilk. Absorption by the infant is unlikely because it would probably be destroyed in the infant's gastrointestinal tract and poorly absorbed orally. It also has a half-life of only 10 to 15 minutes. Based on animal data, an increase in breastmilk cortisol levels might be expected after administration of corticotropin to a nursing mother.[1]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Pearlman W. Glucocorticoids in milk: A review. Endocrinol Exp 1983;17:165-74. [PubMed: 6317337]
Substance Identification
Substance Name
Corticotropin
CAS Registry Number
9002-60-2
Drug Class
Breast Feeding
Lactation
Milk, Human
Adrenocorticotropic Hormone
ACTH
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