Generic Kynmobi Availability
Last updated on Apr 10, 2025.
Kynmobi is a brand name of apomorphine, approved by the FDA in the following formulation(s):
KYNMOBI (apomorphine hydrochloride - film;sublingual)
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Manufacturer: SUMITOMO PHARMA AM
Approval date: May 21, 2020
Strength(s): 10MG (discontinued) [RLD], 15MG (discontinued) [RLD], 20MG (discontinued) [RLD], 25MG (discontinued) [RLD], 30MG (discontinued) [RLD]
All of the above formulations have been discontinued.
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Kynmobi. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: Generic Drug FAQ.
Related patents
Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.
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Sublingual apomorphine
Patent 10,420,763
Issued: September 24, 2019
Inventor(s): Giovinazzo Anthony John & Hedden David Bruce & De Somer Marc L. & Bryson Nathan John
Assignee(s): Sunovion Pharmaceuticals Inc.Disclosed are sublingual formulations of apomorphine, and methods of treating Parkinson's disease therewith. The sublingual formulations are films or strips having a first portion comprising apomorphine particles comprising an acid addition salt of apomorphine and a second portion comprising a pH neutralizing agent.
Patent expiration dates:
- June 11, 2030✓✓
- June 11, 2030
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Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa
Patent 10,449,146
Issued: October 22, 2019
Inventor(s): Barnhart Scott David & Koons Michael Clinton & Hariharan Madhu Sudan & Dubow Jordan & Bilbault Thierry & Giovinazzo Anthony John
Assignee(s): Sunovion Pharmaceuticals Inc.Methods and pharmaceutical unit dosage forms for treating Parkinson's disease in a subject (e.g., an “off” episode in a subject having Parkinson's disease) are described. The pharmaceutical unit dosage forms are films having a first portion including particles containing an acid addition salt of apomorphine and a second portion containing a pH neutralizing agent. The pharmaceutical unit dosage forms can be flexible and have toughness greater than 100 g×mm. The methods can involve administering to a subject having Parkinson's disease a therapeutic dose sufficient to produce an apomorphine plasma concentrate of at least 2.64 ng/mL within 45 minutes after the administration. The subject may be identified as having low uptake, medium uptake, or high uptake of apomorphine administered via oral mucosa.
Patent expiration dates:
- April 19, 2036✓
- April 19, 2036
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Sublingual and buccal film compositions
Patent 10,821,074
Issued: November 3, 2020
Inventor(s): Myers Garry L. & Hilbert Samuel D. & Boone Bill J. & Bogue B. Arlie & Sanghvi Pradeep & Hariharan Madhusudan
Assignee(s): AQUESTIVE THERAPEUTICS, INC.The present invention relates to products and methods for treatment of various symptoms in a patient, including treatment of pain suffered by a patient. The invention more particularly relates to self-supporting dosage forms which provide an active agent while providing sufficient buccal adhesion of the dosage form. Further, the present invention provides a dosage form which is useful in reducing the likelihood of diversion abuse of the active agent.
Patent expiration dates:
- August 7, 2029✓
- August 7, 2029
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Methods of treating Parkinson's disease by administration of apomorphine to an oral mucosa
Patent 10,959,943
Issued: March 30, 2021
Inventor(s): Barnhart Scott David & Koons Michael Clinton & Hariharan Madhu Sudan & Dubow Jordan & Bilbault Thierry & Giovinazzo Anthony John
Assignee(s): Sunovion Pharmaceuticals Inc.Methods and pharmaceutical unit dosage forms for treating Parkinson's disease in a subject (e.g., an “off” episode in a subject having Parkinson's disease) are described. The pharmaceutical unit dosage forms are films having a first portion including particles containing an acid addition salt of apomorphine and a second portion containing a pH neutralizing agent. The pharmaceutical unit dosage forms can be flexible and have toughness greater than 100 g×mm. The methods can involve administering to a subject having Parkinson's disease a therapeutic dose sufficient to produce an apomorphine plasma concentrate of at least 2.64 ng/mL within 45 minutes after the administration. The subject may be identified as having low uptake, medium uptake, or high uptake of apomorphine administered via oral mucosa.
Patent expiration dates:
- April 19, 2036✓
- April 19, 2036
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Sublingual films
Patent 11,419,769
Issued: August 23, 2022
Inventor(s): Bryson Nathan John & Giovinazzo Anthony John & Barnhart Scott David & Koons Michael Clinton
Assignee(s): Sunovion Pharmaceuticals Inc.The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
Patent expiration dates:
- December 16, 2031✓✓
- December 16, 2031
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Sublingual films
Patent 8,414,922
Issued: April 9, 2013
Inventor(s): Bryson; Nathan John et al.
Assignee(s): Cynapsus Therapeutics, Inc. (Toronto, CA); ARx, LLC (Glen Rock, PA)The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
Patent expiration dates:
- December 16, 2031✓✓
- December 16, 2031
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Sublingual films
Patent 8,846,074
Issued: September 30, 2014
Inventor(s): Bryson; Nathan John et al.
Assignee(s): Cynapsus Therapeutics, Inc. (Toronto, CA); ARx, LLC (Glen Rock, PA)The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
Patent expiration dates:
- December 16, 2031✓✓
- December 16, 2031
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Sublingual apomorphine
Patent 9,044,475
Issued: June 2, 2015
Inventor(s): Giovinazzo Anthony John & Hedden David Bruce & de Somer Marc L. & Bryson Nathan John
Assignee(s): Cynapsus Therapeutics, Inc.The invention features sublingual formulations of apomorphine that is a mucoadhesive polymer film or a strip having a first portion including an acid addition salt of apomorphine and a second portion including a pH neutralizing agent, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders by administering sublingually the film or strip.
Patent expiration dates:
- June 11, 2030✓
- June 11, 2030
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Sublingual films
Patent 9,283,219
Issued: March 15, 2016
Inventor(s): Bryson Nathan John & Giovinazzo Anthony John & Barnhart Scott David & Koons Michael Clinton
Assignee(s): Cynapsus Therapeutics, Inc.The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
Patent expiration dates:
- June 11, 2030✓✓
- June 11, 2030
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Sublingual apomorphine
Patent 9,326,981
Issued: May 3, 2016
Inventor(s): Giovinazzo Anthony John & Hedden David Bruce & De Somer Marc L. & Bryson Nathan John
Assignee(s): Cynapsus Therapeutics, Inc.The invention features methods involving the use of sublingual film formulations of apomorphine for treating Parkinson's disease. The methods involve providing the sublingual film formulation and administering the sublingual film formulation sublingually in the mouth of a subject by contacting sublingual mucosal tissue with the film.
Patent expiration dates:
- June 11, 2030✓
- June 11, 2030
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Sublingual apomorphine
Patent 9,669,019
Issued: June 6, 2017
Inventor(s): Giovinazzo Anthony John & Hedden David Bruce & De Somer Marc L. & Bryson Nathan John
Assignee(s): Sunovion Pharmaceuticals Inc.Disclosed are sublingual formulations of apomorphine in unit dosage form formulated for sublingual administration, where the unit dosage form is a mucoadhesive film containing a pH neutralizing agent and apomorphine particles containing an acid addition salt of apomorphine, and where the mucoadhesive film is formed by the steps of: (i) combining a film-forming mucoadhesive polymer, apomorphine particles comprising an acid addition salt of apomorphine, and a solvent to form a mixture; and (ii) pouring the mixture onto a surface and evaporating some of the solvent to form a first film comprising the apomorphine particles, where the steps further include contacting or impregnating the first film or mixture with a pH neutralizing agent to produce the mucoadhesive film containing the apomorphine particles and the pH neutralizing agent.
Patent expiration dates:
- June 11, 2030✓✓
- June 11, 2030
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Sublingual apomorphine
Patent 9,669,021
Issued: June 6, 2017
Inventor(s): Giovinazzo Anthony John & Hedden David Bruce & De Somer Marc L. & Bryson Nathan John
Assignee(s): Sunovion Pharmaceuticals Inc.Disclosed are methods of treating Parkinson's disease by (i) providing a pharmaceutical composition in unit dosage form that is a film having a first portion including apomorphine particles containing an acid addition salt of apomorphine and a second portion containing a pH neutralizing agent, where the film contains the acid addition salt of apomorphine in an amount effective to treat Parkinson's disease, and (ii) administering the film by placing the film sublingually in the mouth of the subject and contacting sublingual mucosal tissue with the film.
Patent expiration dates:
- June 11, 2030✓
- June 11, 2030
More about Kynmobi (apomorphine)
- Kynmobi consumer information
- Check interactions
- Compare alternatives
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: dopaminergic antiparkinsonism agents
- Breastfeeding
Related treatment guides
Glossary
Term | Definition |
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Drug Patent | A drug patent is assigned by the U.S. Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation. |
Drug Exclusivity | Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant. |
RLD | A Reference Listed Drug (RLD) is an approved drug product to which new generic versions are compared to show that they are bioequivalent. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application (ANDA). By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart. |
Further information
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