Has anyone taking zoloft experienced muscle and body aches while on the medication? I am an avid exerciser and I have pulled and strained several muscles since starting the meds. I also am in a constant state of overall muscle achey-ness and stiffness. It seem very coincidental to me that it al started after the zoloft and has persisted since.
Zoloft and muscle aches and soreness?
Question posted by verve on 28 Oct 2010
Last updated on 14 November 2022 by Anonymous
9 Answers
I took generic Zoloft (Sertraline) 25mg for about 6 weeks and it helped my mental issue. I then started getting headaches, blurred vision in my left eye, and muscle and joint pain. I stopped taking it and 2 months later the pain is still pretty bad. I had no pain before taking it. Nothing else changed in my life during this period so I am 100% sure that it is the meds. I went to my chiropractor for an adjustment and he said he couldn’t believe how tight and locked up my neck and back were.
Long shot, but if verve is around. I’d love to know how long after going off Zoloft it took for this to get better.
I’m experience something similar, have been off of Zoloft for a week but am not feeling better.
Yes, very bad muscle aches, couldn't hold my head up, chewing and swallowing was almost impossible. Walked hunched over because I couldn't stand up straight. Generic Zoloft has ruined my posture terribly. Doing exercises to try to correct. It took only three months 50 mg a day to become disfigured.
I am having the same symptoms. I too had a minor injury (pulled a muscle in my back) prior to starting the Zoloft and it has never really healed. Lately, I've noticed soreness in my thighs - like you said - it feels like after a workout.
I'm at 150mgs now. I'll talk to my doctor about it when I see her next. But it's good to know that if it gets to be too much I can make it go away by stopping the pills. A shame though because so far Zoloft has been way better than the Effexor I was on before. Ah well they do say that there can be quite a process of discovering the right drug or mix.
Glad to hear you feel better.
You know, I had some general aches and pains before starting this drug, as I was recovering from what my doctor called a virus, but what I believe to be mold exposure sickness. Either way, I had some general aches and pains. After starting this med about 6 weeks ago, I noticed the awful leg cramps. My doctor thinks it's unlikely, but I feel that the zoloft is playing a part. I have cut my dose down to 12.5 and would like to stop it altogether. Would you mind telling me how much you were taking and how long it took before you felt it was out of your system?
Sorry, for the late reply!! This e-mail got shuffled to the bottom of the stack, so to speak and I just remembered it.
My zoloft experience was not very cut and dry. I had been on Lexapro for 5 years and it was wonderful for me, until the last year or so, when it slowly stopped working. My Dr. had me start coming off the Lex slowly as I was starting on the the Zoloft slowly. So the whole experience was a bit of a mishmash in my brain. I had some side effects and my Dr. kept bumping up my dosage, thinking that that would make it better some how... after a couple months I was at 150mgs. I believe. I am a petit person so thats kind of a lot. Anyway when we decided it wasn't working she started having me taper off of it and with her permission I went completely off with out going on to another med. I just wanted to clear my system out before I started taking something else.
Once I was off it the detox process took several weeks and was very brutal! I know it's not recommended to go completely off but I just needed to and I am glad I did. It was not the right medicine for me and my rough time going off of it might have been from that.
I will say this, everyone reacts to these meds differently, thats why it's so hard to find the right one. Honest Dr. will tell you that no one really understands a lot about these meds and there is no way to know which one is going to be right for some one. It's trial and error. My Dr. told me she had never had anyone have muscle aches and cramps and pain, but that on these meds "anythings possible".
I am now on effexor and it is working well for my anxiety, but I do have some body ache and muscle pain. It's less than it was on zoloft and it is worth the relief I am getting from anxiety.
I hope this helps some how! Feel free to ask more questions. I am glad to share my experience!
To anyone interested in this question, I am off the Zoloft now and the problem is gone. I am still dealing with the aftermath of what ever it did to my muscles (i.e.- pulled groin muscle and strained neck muscle are still healing) but I am no longer feeling the aches and stiffness I was and I haven't injured anything new since I have been off of the Zoloft.
Clearly this is no scientific conclusion, but I am totally convinced that all of it was from the Zoloft.
I am glad to hear your better! They are finding more and more evidence that medicines that effect your seratonin level also effect your muscles and bowels... I agree it was prob Zoloft.
Wishing you a happy Holiday!!
Hello there. I started taking Zoloft years ago and had what you describe My calve muscles especially and hamstrings were very tight. They did not connect it Zoloft use back then. I just lived with it and thought it was Fibromyalgia. In retrospect it was the Zoloft all along.
I got very ill with Serotonin syndrome last year and the muscle stiffness progressed to spasms and hyper reflexes, and ended with me going into "seizures' of uncontrollable jerking all over my body.
I quit taking Zoloft and the muscles returned to normal. I had also been diagnosed with irritable bowel syndrome and that went away too.
Today I am med free and slightly depressed but I would rather deal with the depression than ruin my body and mind with Zoloft.Thats just my opinion, of course.
I am sorry to hear this, but a bit relieved also! =P I am very active and it has been so hard not to be mobile and active. I am only 33!
I agree with you, at this point my anxiety an panic disorder will be a welcome relief from all that the zoloft has done to me! I was on Lexipro for 5 years and it worked wonders for me, until 6 months ago when it seemed to just not be effective any longer. My anxiety returned and my Dr. switched me to zoloft, it has been a grab bag of wackiness since then! I am going off of it currently so that's good.
What is life if not an adventure right? =)
This is my second year of taking zoloft (seasonally for SAD) and I woke up with my fibro aches. THIS year I suspect it's related to the zoloft - LAST year I made no connection. It didn't take much searching to find this thread. I'm contacting my doctor and starting to back off of it today. I'll TRY to get an update posted here if the pain reverses itself. Thanks for sharing! (zoloft has comments that it's used as a treatment for fibro).
Meanom
I have been taking zoloft for a couple of years now and have developed severe neck and shoulder stiffness and pain and also restless legs. I didn't realize it could be anything to do with zoloft but i do now. I will be coming off it pronto. Thanks
I am currently on 100 ml of Zoloft. I have terrible body stiffness. Has anyone else felt with this? It’s been a month since starting. Neck and back were still but it’s continued to get worse. I need to probably change meds but don’t know what to do next, as I have tried a ton of them and never can continue due to side effects.
I finally got off Zoloft after five years and now I have "feelings" again and more energy and am happier. As far as stiffness including joint or connective tissue pain I swear by Glucosamine, even once a day works and there are no side effects.
Very stiff (rigid) muscles is a serious side effect, do contact your Doctor immediately and let him / her know what you are experinecing.
For future reference:
Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have any of these serious side effects:
very stiff (rigid) muscles, high fever, sweating, fast or uneven heartbeats, tremors, overactive reflexes;
nausea, vomiting, diarrhea, loss of appetite, feeling unsteady, loss of coordination; or
headache, trouble concentrating, memory problems, weakness, confusion, hallucinations, fainting, seizure, shallow breathing or breathing that stops.
Less serious side effects may include:
drowsiness, dizziness, tired feeling;
mild nausea, stomach pain, upset stomach, constipation;
dry mouth;
changes in appetite or weight;
sleep problems (insomnia); or
decreased sex drive, impotence, or difficulty having an orgasm.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
Take care and I hope you get well soon.
Thanks.
What I am experiencing is more of a mild dull ache. It just feels like I over exercised but, it's felt this way for over a month and a half now.
I am already in the process of going off of the zoloft because of other side effects. It really didn't do good things for me at all! I was more curious at this point. I am hoping as I wean of of the zoloft this pain and achiness will go away.
Thank you for responding!
I am more than happy to help you, and you are welcome.
Take care
Been on zoloft for several years. The longer I was on it, the more side effects kept showing up. Two of the most troublesome were left arm triceps and bicep muscle aches along with a tendinitis/arthritis like symptom in my elbow. This elbow ache, also in the left arm was 24/7. Occasionally, I would get "sympathy pains" of the same nature in the right arm. The final straw was my blood pressure shooting up rather suddenly. My BP is normal at 130/80 and always has been... give or take a few points.
Finally I quit and slowly phased it out. I was taking 50mg and eased back weekly. The elbow ache eased up and disappeared (after 2 years of 24/7) within 2 days. The high blood pressure eased off and went back to the normal range within 4-5 days. The muscle appears to be the last to go, of all symptoms... it's been 6 weeks now and they are easing up and will hopefully be gone in another week.
Other symptoms included:
1. Weight gain of 30 pounds (now dropping)
2. Sleeping too much. Back to normal of 7-8 hours nightly)
3. No initiative/get-up-and-go. (Greatly improved... get more done now in one day than I use to in a week)
4. Excess flem in air passages (now gone)
5. Excess growth of finger and toe-nails along with streaky lines under them. (disappearing as the nails grow out)
6. Excess thirst, hence water retention... (now gone)
7. Skid marks on the skivvies... constantly. :-) (now gone)
8.Reaction and excess sweating in warm... not hot... weather. In the 80's. (Gone)
9. Hard to think straight and remember things. (Gone)
vfinn- Thanks for your comment. I am learning more and more that these meds effect us in so many ways! The zoloft was not good for me at all and I am off of it now. It seems like a lot of the anti-anxiety meds effect my muscles and cause soreness and pain. I am on effexor now and it has a similar effect on me, it also has helped my anxiety and panic too. So for now I ice and take advil, and deal with the pain because it's SO much better than anxiety!
Related topics
zoloft, panic disorder, social anxiety disorder, anxiety and stress
Further information
- Zoloft uses and safety info
- Zoloft prescribing info & package insert (for Health Professionals)
- Side effects of Zoloft (detailed)
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