In the package insert, male infertility is indicated as a possible side effect of the drug. On the other hand, it is known as an anti-oxidant, which may be beneficial for fertility. Thus, should allopurinol be avoided by men who have low sperm quality or the other way round?
Why allopurinol would cause male infertility?
Question posted by DereviaS on 4 Aug 2010
Last updated on 8 August 2010
Added 5 Aug 2010:
What's the possible mechanism of this side effect?
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Answers
Inactive
5 Aug 2010
Uses
Allopurinol (Zyloprim) is a prescription medication approved for preventing:
Gout attacks
High uric acid levels due to cancer treatment
Prevent elevation of blood uric acid in patients undergoing chemotherapy for the treatment of certain cancers and in patients with recurrent calcium kidney stones.
This drug is not used to treat male infertility.-It is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronic gout.
Off-Label Allopurinol Uses
Mouth sores due to chemotherapy (used in a mouthwash form)
Prostatitis (inflammation of the prostate gland)
Leishmaniasis (a parasitic infection)
Take care
DereviaS
5 Aug 2010
Thanks. Actually, the indications are well known. The question was whether and how the drug causes infertility, rather than whether it is used for treatment thereof.
Inactive
6 Aug 2010
Ok, No one has all the answers, I do not..I am here to help as much as I can I am a humble person, in this support group we are friends we are a virtual family, we do not try and prove who knows more or less... I do not care about the points. You knew the answer to your question..but still you posted it, I only tried to help, and you are new to this site..maybe you are trying to impress me (us) ... but that is not the way it works..my new friend... this time you have upset me and will not be humble cliik on my avatar (my face / logo ) and then on my stats.- So you know who I am.
Inactive
6 Aug 2010
By the way you ask and comment , I pick up that you must be a bodybuilder.-
DereviaS
6 Aug 2010
No, I didn't know the answer, I don't know now either. I am a user of this medicine and I'm anxious about this side effect. Sorry.
Related topics
Further information
- Allopurinol uses and safety info
- Allopurinol prescribing info & package insert (for Health Professionals)
- Side effects of Allopurinol (detailed)
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