When is the best time to take Zoloft?

I've been on Zoloft for 20 years and always take in morning.Its worked like that for me.

I would actually recommend taking it at night time. That time worked best for me.

I was told to take it early. Its suppose to "set your day to be a good one. I was having trouble sleeping and that's he said... AM... Hope this helps!

HI! I'm sure you've received a lot of good information on Zoloft. I used to take it myself and I agree with you, that it does make you dopey. I always took mine at night. It helped me sleep and I felt better the next day. Antidepressants slow your nervous system down and help you concentrate and "worry" so much about anything and everything. I hope this helps!

I would tAlk to the doctor to see if it's okay to take it at night.

yes I feel sleepy at work in the morning, if I take it then.

Hello I take my Zoloft every morning. I'm on 100mg. Some say it makes them sleepy but it don't make me sleepy. But everybody's different.

Hello I started taking Zoloft 6 weeks ago I was fine the first few weeks absolutely no side effects just a bit thirsty. Then last week I started getting extremely tired and dizzy spells I even had to go for a nap during the day.
Has this happened anyone before ? Should I change the time I take it to night time.? Thank you for your help

I am just starting zoloft but when I was on paxil I had insomnia even though I took it in the mornings. My doc prescribed 50mg trazodone, which is also for depression and anxiety, to help me fall asleep. I take that with a 250 mg of magnesium and a 10 mg of time release melatonin to help me stay asleep. It works. Give it a try.

You can take it anytime of day you choose. If you're tired in the morning maybe it will help you rest easier at night. Just try to take it at the same time everyday.

In the morning.

Be careful of the possible side effect of Zoloft. This group of antidepressants can cause tinnitus or ringing in the ears.

I have been taking Zoloft for several years and have found it to be the best antidepressant as well as anxiety.
I take mine 3x a day.. You will eventually get over making you sleepy. When I only took one dose a day I took it at night
Hang in there It will make you feel better. Good luck

Take it in the AM first, then if you have no ill effects during the day (most often nausea or drowsiness) after two weeks (allow time for the side effects to lessen as your body adapts to the drug), then continue with AM dosing. Only if you have problems with tolerability should you switch to supper or bed time dosing.

All SSRI drugs affect sleep architecture, and while sertraline stays at a relatively steady state in the system (half life is ~26hrs on average), there will always be a bump in serum level after a dose, which is best not placed during the time of day when you want to sleep.

We do not fully understand the effects of SSRIs on sleep, but in theory these changes in sleep architecture could be causally related to increased fatigue that is seen in those taking this class of medications.

This is a minor concern, so don't worry if you have to take the drug in the evening. It's a tweak, not a big deal.

Zoloft may be taken morning or evening, with or without food, or the dosage may be split if directed by your doctor. It should be taken at the same time each day.