I have been on Trintellix for about 3 months now. Started out on 5mg and was take up to 10mg. When I started the 10mg I started to get nauseous but would never vomit. I would take it at night because of this side effect. It has helped with depression and anxiety.
Last week all of a sudden I got bloated and had very bad stomach pain and diarrhea. I had this for 4 days. I had no changes to any medications. I was not running a fever or vomiting.
My primary suggested that I go back down to the 5mg and see how I do. I took the 5mg for one night and the next day I started feeling better.
But last night I took the 10mg thinking that it would be all right. Well, this morning I have the same stomach pain and diarrhea.
My question is, can you get side effects after being on the medication for 3 months, just all of a sudden?
Trintellix - stomach pain and diarrhea?
Question posted by LauraStrong51918 on 5 Sep 2019
Last updated on 15 January 2020 by MonkeysMommy2008
Answers
I started a few months before you taking 10 mg. The nausea wasn't bad at first but when it didn't go away, I figured it must be something else (I had read the side effects would go away after a few weeks). Plus, it wasn't every time I took it, so I stopped associating it with Trintellix. In October, 5 month after starting, the nausea started to escalate to vomiting. I'm one of those that don't go to the doctor unless I am dying and the vomiting was not daily or anything, so I didn't do anything about until October 20th. I had the worst pain ever in my stomach and was doubled-over in pain. Pretty soon I started vomiting but it wouldn't stop and then the diarrhea started. I figured it was some really bad food poisoning but all I had that day was canned soup. Anyway, it would not stop and the pain was unbearable, so my husband took me to the ER. I was there for two days and they could find nothing wrong after running a bunch of tests. I felt fine once I was discharged, so I went back to work. I was talking to a friend at work and she said "hey, didn't you say you started taking Trintellix awhile back?". I told her that I was taking it and she proceeded to tell me that two of her relatives ended up in the ER with the same exact symptoms and were taken off Trintellix. They had no issues after that, so I stopped taking it immediately. I have had no stomach issues whatsoever since October 20th.
The answer to your question is yes, you can get side effects after 3 months. - at least that has been my experience. I took Trintellix successfully for almost a year. At first I lost weight, and I had extreme constipation problems. I felt good as far as anxiety goes, but I started to get bloated, belly bloat, and started holding fluids, especially in my face and around my midsection. I reached a point where I could no longer tolerate the side effects, although I had had almost a good year on it, despite the constipation which I treated with Miralax, dulcolax, and probiotics. I put on 10 pounds, which I am still carrying around and quite frustrated about...
Related topics
depression, diarrhea, pain, nausea/vomiting, major depressive disorder, stomach pain, stomach, trintellix
Further information
- Trintellix uses and safety info
- Trintellix prescribing info & package insert (for Health Professionals)
- Side effects of Trintellix (detailed)
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