So far the side effects I've had are minimal. I feel tired sometimes and take a nap (twice in one week). The first day I took a morning and evening dose I felt a little loopy. This will be my second day with two pills, I'll see if the loopy feeling happens again. I do notice that I don't feel like I have to eat every treat that is placed before me right now. With all the Christmas goodies around that is a good thing!