Hello. I have just started (4 days in) taking Pristiq to help with my GAD anxiety which can also slip into depression. I have 100mg tablets and the doctor is getting me to go with 1/4 tablet (25mg) for the first 7 days, then 1/2 tablet (50mg) for the next 10 days, then will go back and see her. A couple of questions and observations:

1. I have seen some info regarding Pristiq being a "slow release" medication and that I should take the tablet whole but my doctor wants me to split the dose to "taper on". Is this ok?

2. I have seen very small glimpses of some normality and I think that is due to me accepting medication is needed. The majority of the time my anxiety is high with a knot in my stomach for no reason, irrational fear, no motivation, and no excitement. Do you think these glimpses will increase as I continue to take and get to my 50mg dose?

3. I have heard the first 4 - 6 weeks is the toughest, any advice how to survive this journey. I feel like I am teetering on a cliff of insanity and just cant get away from myself.

4. Any other pristiq users who have been on it for a while who feel great? (Eg. Being able to feel happy, joy, excited, expectant etc instead of non-motivated or fearful?)

Thanks.