... all day, still very nauseated and wondering whether to take another one tonight. How long is nausea expected to last? Dr. has switched me to this from 100 Mg zoloft for panic/anxiety disorder
Just started on 10mg Brintellix last night, very nauseated, sleepy this morning. Have not felt good?
Question posted by angelwoz on 26 May 2014
Last updated on 24 October 2017
10 Answers
Heins
24 Oct 2017
It was prescribed to me Brintellix.
So far I have fatigue and starting with the nausea. I´m on my 5th take with only 5mg. I have read many reviews on the internet and saw it was a "normal" side effect. My weight is low, I´m only 53kg and this nausea for sure will decrease my appetitte and in consequence I will get more skinny :(
I take also 12.5 mg of ambien in the night.
My anxiety is still the same, and doctor says we are slow but still on track.
Did the nausea vanish for you?
WildcatVet
24 Oct 2017
Hi, Heins! Side effects from Brintellix (Trintellix or vortioxetine) and most other antidepressants generally only last a few days to a week or so, but they get better every day.
You are not alone: *Very common (10% or more): Nausea (up to 42%)*
Try taking it with some milk, yogurt, soda crackers, ginger ale or any bland, mild food. You could also try taking it at bedtime.
Don't worry about getting skinny... you won't... the side effects won't last that long. Worrying only makes your anxiety worse! :-)
Best regards and I hope you feel better quickly.
MRaeH
5 Feb 2017
For anyone struggling with the nausea I get it! I ended up in the hospital from vomiting so much and I NEVER throw up... in fact the fear of it is often the cause of my anxiety. My doctor prescribed me zofran and it's made a world of a difference!
kohouse
15 Sep 2016
Tums may help.
clendeninp8054
11 Sep 2016
i am on 5mg No nausea but a little trouble sleeping... Maybe you could ask your doctor for compazine for the nausea brintellix is in the same family as zoloft... have you tried that?
happivan
28 Aug 2016
I have been taking 5mg in the morning for 2 months now and am still dealing with terrible nausea for the first 3-4 hours of the morning. Have the feeling that I need to crawl back in bed and lie down. Going to ask the doctor to switch to something else. Was supposed to move to 10mg after 2 weeks and never did because of the nausea. Came off Fluoxetine after 5yrs on it and can tell that Trintelix is nowhere close in efficacy to it.
angel99903
25 Oct 2014
My mom/ best friend just died this past Monday from pancreatic cancer!!! So i went to the doctor today n she gave me samples of 10mg brintellix, .5clonopins, n ambiens to sleep is it oooook to take all these together??? N should i start the brintellix tonight or in the morning???
Sumo
25 Oct 2014
There is a drug interaction feature on this site. Type in drugs & it will tell you. I know the brint & klonopin are fine not sure about ambien. Been on brint 6 weeks. Take in morn with food, no nausea but diarrhea. Take pepto for that. Good luck. So sorry about your Mom.
clendeninp8054
11 Sep 2016
So sorry for your mom and the pain you are going through My husband and I had cancer at the same time. He died last year at 44 I am still fighting with mine. I don't there is one medication out there that can fix broken hearts...
clendeninp8054
11 Sep 2016
think
WantMeBack2
15 Sep 2014
I just started Brintellix today, 10 mg, with a large lunch. I am slightly nauseated now, 3 hours later, not too severe. I will update my progress, and look forward to reading others experiences - thank you for sharing.
I have never posted in a forum like this, so please forgive my naiveté.
I was on Lexapro 10 mg for 6 years for GAD and Anxiety. Which worked pretty well, up until a couple of months ago. I became extremely depressed and for the first time in my life had suicidal thoughts. My pdoc tried increasing Lexapro to 20 mg - made anxiety worse, and I was very tired, so he decided to switch me to Brintellix and gave me Klonopin for anxiety attacks. the tapering off the Lexapro was one week - very dizzy and fatigued.
I am very interested in how others are tolerating this "new" drug, and whether it is helping BOTH the depression and anxiety, as well as side effects that come, and perhaps taper. I don't know how long its supposed to take to either feel better, or stop having side effects.
Its gotten so bad that I applied for short term disability for 8 weeks from work, thinking that if it takes weeks to determine efficacy, it could take another several weeks to try something else. I had no idea that there was a shortage of Psychiatrists - I was quite surprised when my pdoc told me there were no Psychiatrists in my area accepting new patients! Hopefully that will not affect my STD request, but I am certainly becoming more aware of the ins and outs of psychiatric care (good episode last night on 60 mins on shortage of available beds for inpatient and access to outpatient.
thanks everyone. Wishing everyone happiness without anxiety.
Sumo
23 Sep 2014
I was told to take in morning with food. 10mg @d. Haven't had any nausea. Two weeks & have had 3 days of the trots. I know all these meds take time and we all react different. I'm on klonopin, 5mg, 3 times@d. Bad anxiety also. Makes me very drowsy. I had to go thru ER to get to a psychiatrist. Amazing! I also have serotonin syndrome, so my drugs are limited. I am so hoping this is the ONE! Life has sucked lately. Wish us all well & hopefully we can help each other out. Sounds like we can all use help!
angelwoz
23 Sep 2014
I only stayed on the brintellix for 2 months. The dr and I both decided it wasn't working for me. Was then switched to Viibryd which made my anxiety/depression worse. Dr started me on Paxil 2 1/2 weeks ago. Still feeling nausea, foggy headed, dizzy and anxious. Very tired of trying new meds that I don't tolerate well and not seeing any positive results. I too am thinking of applying for time off from work or disability. Between the depression, anxiety and side effects from meds it is overwhelming and hard for me to make it through the day at work. Searching for answers...
angel1662
26 May 2014
hello angelwoz
I am sorry you r not feeling well ... I am on brintellix and have been for about 2 mths now..I started at 5/ then went to 10/ now am on 20 mg's I get akethesia from alot of the older ssri's/snri's so my psych decided to try me on this one... I didn't get the akathesia..I did get the nausea,but I fought threw it/ it has gone away... no more nausea..when I would get nauseated I would eat a couple crackers or a mint..As far as it making me sleepy in the morning never had that issue at all..but as we all no we r all different..I take my in the daytime at a certain x each day, but keep it consistent... if you just started it my advice would be to stick it out for the nausea does go away... and there is always something you can take for nausea... especially if it turns out this is going to be the med that works for you one day is just not enought time you need up to 6 to 8 weeks on this med to reach it's thereputic level... good luck and keep us posted..
angelwoz
26 May 2014
Thank you. I'm trying to stay positive but this nausea is almost unbearable. I can't hardly eat anything which is making me feel weak, no energy at all. ;(
sthrift2
12 June 2014
Angelwoz,
Wondering how the Brintellix is working out for you. Did your nausea ever subside? I just started 2 days ago and I'm miserable with the nausea but hate to give up too soon. Thanks for sharing.
angelwoz
12 June 2014
The nausea is better but I have only been taking 5 MG for the past 2 1/2 weeks. I am experiencing a lot if other side effects that are bothersome also; bruising, headaches, dizziness, memory is foggy and I am forgetful, which is not normal for me.
I am dreading moving up to a higher dose.
I can't tell if it's really doing me any good or not.
Would love to hear more responses.
I was given this medicine for GAD not depression.
Thanks
angel1662
14 June 2014
hello sthrift2
I have been on brintellix for over 2 mths now... everyone is different as you well no..you have only been on it for 2 days so I say you have to give it up to 6 wks to reach it's therapeutic level... I started at 5 mg's a wk later on 10/ now am on 20 mg's... when I first started yes the nausea was bad but nothing I couldn't handle... and as time went on it has subsided completely... I say give it time dear..It's helping me..hope it helps you..GOD BLESS..
angelwoz
14 June 2014
Anyone experiencing other side effects besides nausea? Bruising, headaches, dizziness, BP issues?
Aratph
25 Oct 2014
I have just started taking 10mg Brintellix and I'm so nausea. I feel really bad, I have no desire to do anything. I was taking Lexapro and I felt fine except for sleepy so I took it at night. So when I went to my doctor, he said Brintellix is better... less side effects and no weight gain.
nikkijo
16 Nov 2014
I too am on my third day of 10mg Brint... first two days I took it in the morning and OMG the nausea is Brutal! I am going to try taking it tonight at bedtime to see if that helps. I am trying to "push thru" and get to the 6-8 week point to give it a fair shot... I was on 60 mg of Cymbalta and we are switching to Brint to see if it helps me not gain more weight and possibly will "let me" lose weight... I am not on it for depression, I sustained a brain injury 13 years ago in a car accident (level 3 TBI) and Cymbalta helped me to keep things on an "even keal" due to the chemical imbalance caused by the TBI.
Oandlomom
7 Feb 2015
Zofran is amazing for nausea. Only side effect I get is a moderate headache which is easily taken care of with Advil.
Inactive
26 May 2014
The nausea should subside in about a week. My doctor told me to cut the 10 mg and only take 5 mg the first week, by doing so I had less side effects such as nausea.
angelwoz
26 May 2014
Thank you. The nausea is overwhelming :(
Is anyone else on here taking it for panic and anxiety?
Inactive
26 May 2014
If you start a new question and ask about panic etc. Other members will see it.
Can you cut your pills in half and only take 5 mg? Your nausea should go away if you cut to 5mg.
nicnickk
14 Jan 2015
Does Brintillix help for panic and anxiety?
Inactive
14 Jan 2015
Hello nicnickk, it didn't help me with anxiety, but I didn't give it the full 8 weeks as some members suggested. I hope you find the right medication as anxiety and panic is so horrible. Try starting a new question asking if brintlx helps with anxiety and panic attacks and hopefully you'll get more answers. Good luck!
kaismama
26 May 2014
It will wear off soon. You should probably be taking it in the morning.
angelwoz
26 May 2014
Pharmasist suggested taking it at night to help with the nausea.
MA07
2 June 2017
I agree take it in the morning for sure
Related topics
zoloft, anxiety, panic disorder, nausea/vomiting, brintellix
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- Zoloft uses and safety info
- Zoloft prescribing info & package insert (for Health Professionals)
- Side effects of Zoloft (detailed)
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