I have been taking 50mg of sertraline for anxiety for 16 days and the side effects are still really bad. Sweating, hot flushes, headaches, nausea, waves of anxiety and panic, running to the loo and generally feeling awful. The doctor doesn't know if this will settle or if I have Serotonin Toxicity so they are unsure if to take me off them. It seems a shame to be three weeks in and to have to now try something new. I have never felt so bad. Has anyone had a similar experience??
Sertraline - How long do the side effects last?
Question posted by Joanne888 on 18 Oct 2014
Last updated on 26 November 2024 (4 weeks ago) by Mtnsgirl
42 Answers
I took Sertraline 50 also which was a low dose Had all the side effects you mentioned It is different for everyone but usually takes a couple of months to level off Also every time they increase the dosage the side effects kick back in Some people are lucky they have few I will say that it was starting to help me with panic attacks and anxiety I weaned off it Trying not to take ssris as I do not tolerate them well However it’s hard They have to try and see which one works for you so it could mean a change They want me to try Lexapro next Sometimes it takes a few months but then it really has helped many feel so much better It is trial and error and very tough to go thru!! I understand how u feel
Do not give up, push through it, it took about 2/3 months, definitely a game changer. I would look through the reviews everyday this gave me hope to get through the worst off , Always said I would come back, as this helped immensely. I did have to push myself to do this throughout. Even a little at a time. This built up over time giving me my motivation n love for life again. Make a point of getting out, stick to it. I didn’t want to do anything. I made myself do it. Hating every minute of it, just did it. Even doing the smallest thing each day, will get you back to you. Believe you can do it, cause you can. It will just get better each. Do lots of positive affirmations even if you don’t believe it. Take it from me it works. It worked for me. I do some volunteering, I have starting seeing someone. I got myself out off my negative thinking replace it with a positive eventually you will start to believe it n get stronger ever day. Be good to yourself. Goodluck, you can do this cause your stronger than you think x
Hi , I have been taking Sertraline for 22 days and have the exact side effects , except the anxiety and trembling last fro 5am til late at night , I have asked my Doctor how long this will last and she couldnt tell me , I can hardly function
Does any people in this group can says any positive comments about sertraline. I’m been on 25 mg 3 months and want to up 50 mg.
It's my 6th day on sertriline. During the night I woke up feeling calm no anxiety and panic. Woke up this morning it's through the roof panic anxiety intrusive thoughts I feel I'm going crazy please tell me it will get better I'm on 50mg I'm also tapering off mirtazapine 15mg at night
I’m on day 21, 50mg increased to 100mg a week ago. The side effects are horrific and I don’t know if I can continue with the meds. Constantly nauseous or vomiting, insomnia, sweats…..it’s just awful and no signs of letting up.
Did you have these side effects on 50mg or just when you increased your dose to 100mg?
Yes but not as bad, I could still go to work, now I can’t. I’m thinking of stopping the tablets, I’m so I’ll.
Thank you for answering, I feel alone with the nausea
From my own experience, and I am not a medical professional, it took roughly 5-8 weeks for symptoms to settle and to feel better. I started off at 25mg and on day seven moved up to 50mg, that was when my symptoms started. For me it was insomnia, diarrhoea and a funny tummy. By six weeks all those symptoms resolved.
I am always surprised when doctors increase the dose before allowing the 4-8 weeks that it normally takes for the medication to work. My doctor reassessed me at the eight week mark once She could see that the medication was working.
It sounds as though the jump from 50mg to 100 was too much for you to handle. If it were me I would ask my doctor to reconsider taking me back to 50 and allowing time for it to work before making any more adjustments. With the 25mg tablets availability it might be easier to jump to 75mg if 50 is not helping.
Are you taking the tablets at night? I found the insomnia was worse when I did that so switched to lunchtime. I also do much better taking them after a good meal rather than on an empty stomach.
There is the possibility that sertraline is not right for you but again I would say it is best to continue for the 4-8 week period before making a decision. In saying that if your doctor is concerned about the symptoms he might suggest otherwise.
I take them in the morning. Had an hours sleep last night. Just in my dressing gown all day. I’ve lost nearly a stone in 3 weeks because I can’t keep any food down. I will be ringing the Dr at 8am when they open tomorrow after the bank holiday. It’s no way to live like this. Thanks for your reply, it does help.
The side effects are unpleasant and it doesn’t seem fair that something designed to help you can make you feel so unwell in the first few weeks. Read the reviews here, many people experience similar side effects and for most it does past. I wish I could fast forward you a few weeks in order to show you the brighter side.
In the meantime if you can get some magnesium powder and add it to a glass of water before bed it is a good, natural sleep aid. Sending virtual hugs to you. Let us know how you go with your doctor
My doctor started me on 25mg for a week, it was perfect. No side effects. Even started to feel my mood becoming better. I switched to 50mg that 2nd week. OH MY!! It was terrible. Migraine for hours, anxiety increased. I took 50mg for 2-3 days and my doctor switched me back to 25 mg. No migraines. Anxiety isn't as bad. My mood is better. I'm not ruminating as much. I'm in my 3rd week, so I'm looking forward to feeling the full therapeutic effect. I've taken Prozac, and a few other antidepressant drugs, and never felt a major change. Zoloft so far is great. When I was on the 50mg I was going to try to stick it out, but it didn't seem worth it if I'm so miserable, but my doctor said not everyone needs the higher doses. Zoloft is good so far!
I just finished my 1 week of Zoloft at 25mg... just started 50mg 2 days ago... I was on Prozac for 3 weeks and I was having body sensations, palpitations etc... I hated it so they switched me to Zoloft... I have been getting the body sensations and a lot of anxiety. I am riding through it but the palpitations scared me, Cardiologist said I was fine after wearing a heart monitor... all the things I am reading are reassuring... this is what these SSR's do... they gave me lorazepam in case I have a sever attack... I hope the Zoloft works because after years on Lexapro, a few weeks on Prozac and now Zoloft I am getting to the point that I'd rather stop all this stuff.
I’ve been on sertraline for 4 months, I’ve been experiencing numb feet. Does anyone have these symptoms?
I’ve been on 25mg sertraline for 3 weeks and the side effects are horrible for me. I wake up with bad anxiety, hot flashes, and very nauseous. I can’t eat anything.. My anxiety is at its highest it’s ever been. My dr wants to change me to Prozac but I’m very scared that the outcome will be the same.
Can anyone give me insight i have took sertraline for a month but wasn't really consistent at first but right at a month i got a high fever that lasted for 6 hours .then 5 days later night sweats im still dealing with for going on 5 days.i went to my doctor and she told me to stop taking it. I have fear of other health problems happening and uneasy about doctors appt today. And im wondering have some else had these problems
I have been taking sertraline 100mg for about 3 months now and I feel worse my sleep is terrible I have terrible tremors in my legs and arms dizziness sleepy no energy and more its awful, I'm now cutting down and getting put on something else fingers crossed it works
Hey I'm 36 and been on them for 2 week 100mg the first week was great now I feel the same as u I feel live I cant breathe my backs hot cant sleep cant eat anxiety right eye has blurred vision
I was taking 100mg of sertraline and that made me feel exactly how Your describing it. So my doctor switched me to the 50mg sertraline and I only had side effects the first day I took it. So I would maybe ask for a lower dosage.? This is my 4th anxiety medication they prescribed me. Sometimes you just have to try new meds to see which ones work but you have to be patient it takes time.
Wish I had a more positive response for you but it took just over a month for a lot of the systems to go away. It worked well for me, I stopped taking it this past Oct. What didn't go away was drowsiness and a little bit of a sexual side effect.
Everyone is different but I was not at your level during the first month. Wish I could say stick it out but I'm no doctor. From what I was told the first couple of months are tough but I needed to be patient.
I started at 25mg then 50 and eventually 100mg. I was tappered off in Aug last year though Oct when I stopped.
Best of luck and take care!
Related topics
hyperhidrosis, headache, anxiety, panic disorder, nausea/vomiting, hot flashes, sertraline, side effect
Further information
- Sertraline uses and safety info
- Sertraline prescribing info & package insert (for Health Professionals)
- Side effects of Sertraline (detailed)
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