Seroquel XR - can serouel make u wet the bed?

yes, frequent urination can cause bed wetting in certain patients

Serious Seroquel Side Effects
Some side effects with Seroquel are potentially serious and should be reported immediately to your healthcare provider. These include, but are not limited to:

• Signs of diabetes, such as high blood sugar, increased thirst, frequent urination, or extreme hunger (see Seroquel and Diabetes)

https://www.drugs.com/sfx/seroquel-side-effects.html

Note: The frequent urination... Could cause bed wetting.