... I keep having 1 to 3 days with no bm or very unproductive BMs. Then I'll have a very, very "productive" bm, followed by hours of diarrhea! It is so frustrating. Usually I'll just try to drink water and wait it out. Sometimes I'll give up and take Immodium. Either way, the cycle seems to continue. My constipation before being on Linzess was so bad that I tried enemas and everything else otc to help. I am told I have IBS, Psoriatic Arthritis and Fibromyalgia. When I was in my early 20's I had constant diarrhea. It lasted years. It was made worse with certain foods and I was trying to stay thin at the time, which didn't help, being that most of the "healthy" foods that I was eating were also bad for my IBS. I had a few good years, and then I got pregnant when I was 29. The entire pregnancy I was nauseous so I hardly ate. I got in a car accident after I had my daughter and my health went on a downward spiral. I was treated for my back, herniated disks from the accident and nerve damage in my leg. I was then told I had psoriatic arthritis and have been on methotrexate. I'm not sure if that is causing the problem. It's frustrating with Linzess bc it does work, and then it's followed by diarrhea! I almost don't want to tell the doctor bc the constipation was so terrible, I don't know what's worse! Anyone else have experience with this? Should I call the doctor? Wait until my next appointment? Should I be concerned?