I've been on Trulicity for 3 weeks now, and most of the side effects are manageable (some transient nausea and sour stomach), but for me the worst is the fatigue. I am exhausted and can barely keep my eyes open, it's as if I have no force or energy at all. All I want to do is sleep. Also I have noticed puffy translucent bags under my eyes, and the skin on my face looks almost sunburnt. I am supposed to bump up to the 1.5 dosage next week, but am a bit afraid to do so.
Monday 20 June will be my third dose. Like you I also fight fatigue. While I have had an issue with this for some time, it is much more pronounced now. I can easily fall asleep at my desk or during meetings. In the evenings I am looking to sleep by 7:30 or so.
According to the literature, this may pass. For now, I rely on 5 Hour Energy to keep me alert. It does help, a little.
If you eventually find the fatigue passing, or find some brilliant kind of answer to hold it at bay, do please let me know!