How long does sertraline need to be work?

Hi, Angie!
Each time you increase your dose it takes your metabolism a little while to adjust to it... usually just a couple of weeks. 100mg is a good middle of the road dosage that may be therapeutic for you.
Give it a bit more time and, as jak said, try to distract yourself with long walks, reading, watching a movie, hobbies, anything you enjoy to take your mind off your symptoms. If you're really struggling let your doctor know.
Try not to worry too much as anxiety is just going to breed more anxiety.
Best regards and you should be feeling better soon now.

Hi! I'm not sure how long you have been on the 100mg dose. It can take about three weeks to really settle into your system and be effective. Sometimes the doctor can prescribe additional medication to help with the anxiety as the sertraline does take awhile to work. Definitely communicate your concerns with your doctor. Try walking outside, yoga and breathing exercises to help as you wait for the medication to be fully effective. Take care.