I've been on lamotrigine for bipolar 2 for 3 weeks now. I started at 25mg for one week, 50mg for one week, and now 75mg for one week. Tomorrow I am starting 100mg, which my doctor thinks my therapeutic dosage would be. (I'm a 24 year old woman). So far, i feel no difference. I dont have worsening, or better symptoms. I'm on no other medication. Hoping for a change soon.
How long for Lamictal/lamotrigine for bipolar 2 to work?
Question posted by Anonymous on 15 May 2017
Last updated on 25 March 2022
3 Answers
I have Bipolar II, the milder form. My experience with Lamictal was not good. At 400mg daily it sent me into mania. Everyone one is different. I wanted to share my experience and hope it will be helpful.
Yes it definitely takes 4-6 weeks to start to notice anything. After you're up to 100mg give it a few weeks. I didn't feel any effects until 200mg. Everyone's body reacts different. It does get very frustrating to go through the waiting game. Best of luck!
How many weeks after reaching 200 mg did it take you to feel a difference? I’ve titrate up to 200 mg over 3 months and have now been on the 200 for 3.5 weeks. Don’t feel much.
Hi, k! It can take as long as 4 ~ 6 weeks of usage to reach therapeutic levels and you're only now getting into the therapeutic dose range (maximum maintenance dosage is 200mg/day). Perhaps giving it time at a sufficient dose will bring about good results.
@wildcatvet does it take 4-6 weeks once you’re at 200 mg?
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lamictal, therapeutic, bipolar disorder, lamotrigine
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