I started using Efudex for about a week, applying it in the morning and again at night, which I don't think I should have done, but it worked quite well. Because of business obligations I discontinued it for 2 weeks, and my skin recovered and looked much better than at first. Now I've resumed on a once a day or once every two days schedule, and after a week my skin is very red and blotchy (as expected), but around one eye it is very red, skin broken, and crusty, and I'm getting a little swelling on my lips. These are both signs to stop and recover, so that's what I plan to do. Does anyone know what the effects are of 1 week on 2 weeks off (repeat) versus 8 weeks of continuous treatment?