I have wanted to stop as I wonder if it is still helping me? I occasionally feel depressed but nothing like before Prozac. My concern is I have been on Prozac for greater than 30 years. Does it get better or is this a lifetime problem? I have been off one month and now I am feeling irritable, angry and mild anxiety. Are these side effects of stopping? Should I go back on Prozac or will these go away?
How long do side effects last after stopping Prozac? I have recently weaned off it.
Question posted by rn87 on 21 Aug 2010
Last updated on 11 February 2020 by Cburke4365
18 Answers
As per my doctor I stopped 20 mg. of Prozac after 8 months of use on December 31. This week my chest has been hurting due to anxiety. Just wondering how long until this drug is totally out of my system and is This a side effect from coming off. If so how long until they subside? TIA
I have cut back on Prozac [40mg] after 33 years of use because it has led to Tardive Dyskenesia, and my doctor is hoping a reduction in Prozac will reduce the symptoms of TD. Even after only a couple of weeks, I am beginning to have all the symptoms of withdrawal.
The person above described my history and symptoms. what other response are you looking for?
I also am having the same symtems as you are. I was on Prozac 40 mg Dailey for two years. I stopped taking the medication in December and it is now March. I am going through all these symptoms also the tiredness agitations and brain zaps. This will get better with time it used to be so much worse. What was everyday is now weaning down. I still feel anger and sadness overcome me, I just keep fighting it. I want off the medication more than anything. Keep at it eventually it will be better.
I was recently tajen off of prozac and put on zymbalta, i had to get the prozac out of my sustom first and had been on it for several years. It took two weeks for it to completely get out of my system and for me, i only delt with mild paronoia and sleelessness til i started my new meds... my sugestion would be to keep a daily diary as i did to monitor how you r doing that way you can dicuss it with youre dr. As coming off of any anti-deptesent/pjychotic drug, can be differnt for everyone
How is the zymbalta working for you. I’m coming off of Prozac but am on Wellbutrin. The Wellbutrin doesn’t seem to work as well but the weight gain and low sex drive is my reason for the switch
The zymbalta seems to wrk realy well, been on 30 mg. As far a welbutrian i dnt know about it. I seem to be haveing a better reaction to the zymbalta and i sleep better at nite as well as my anxity is less. I would suggest you talk with your dr as not all meds are for everyone and the med can make things worse as i have learned from personal experince... merry christmas
I would steer clear of Cymbalta. I was on it for a year and it took me 6 months to get weened off it. Every time I tried to stop, the brain zaps were so bad, I would have to take a small does just to get rid of the zaps. I would open the Cymbalta capsule and count out the pellets to ween off. But when I had gone from 162 pellets down to 20, I still had zaps and dizziness. I had to use Prozac just to get off Cymbalta. It was the only thing that helped the excruciating brain zaps. I was only on Prozac for a month and only took it every three days. It def helped the withdrawals but now that I’ve stopped Prozac, they’re back. I’ve been off Prozac for about a month now and the brain zaps are back full force. I got off Cymbalta bc I gained 75 pounds in one year while on it. This medicine (both Cymbalta and Prozac) are meds from hell and I wouldn’t recommend them to anyone. I had good luck with Wellbutrin for depression.
It takes about 6 weeks to see the good effects but it was good for me. I only tried Cymbalta for my fibromyalgia, which didn’t help me whatsoever. Worst experience ever!!! Stay away from Cymbalta. It’s way worse than Prozac. I have no idea how long it will take for the zaps, dizziness, headaches, fatigue and lethargy to stop. I feel like the withdrawal effects should be gone by now, but no. If anyone can tell me how long the withdrawal symptoms will last after your last dose, I would LOVE to know. I can’t take it and want to know how long this torture will last.
Hi everyone, wish I'd found this guide four months ago. After over 10 years taking 20mg fluoxetine I have finally came off them. Although I'd had no problems whilst taking them I always felt as if I didn't experience real emotions. Finally I started weaning myself off by taking one every other day then cut them out totally. Was ok for first few weeks then I started to experience episodes of sweating, really bad irritability and aches in legs, back and arms. The fatigue was the worst and this has only just started to improve.
There was points where I felt desperate to start taking the pills again but I perservered and I feel practically normal now. Good Luck to you all, it can be done !!
hello heath64. I'm so glad I read your post. I too have stopped taking Prozac after 10 years. ive been stopped 6 weeks today and I have to say its been a bit of a fight. I'm finding dizziness is awful, and tiredness as well-but I will keep going. your post has given me a lot of hope, and I'm just taking a day at a time and hopefully the light at the end of the tunnel will be in sight soon. big thanks to everyone who posted about Prozac. god bless you all.
Thank you for giving me hope. I tapered off over 2 months. I’ve been off completely for a month and I am having issues with concentration and arm and leg pains. Also have no energy. I do cry more easily but that could just be part of my mild depression. Due to the side effects of weigh gain and low sex drive the dr put me on Wellbutrin and then after a month I started tapering off Prozac. I am tempted to start back again but hopefully my withdrawal symptoms will stop soon.
I came off fluoxetine about a month ago and for the past week have been experiencing flu like symptoms. Severe fatigue, walking to the toilet drains all my energy, aches in my joints, fever, headaches. I was rushed to the ER two days ago as my heart started racing and I started shaking uncontrollably. My bloods showed nothing unusual but i have a crp level of 3 which means that my body is fighting something. Could this be from stopping the fluoxetine? I did taper down my dose over about a month
Just to add my 5 cents worth, I too have recently decided to stop taking prozac. Been on them for about 10 years at 40mg a day.
First 2 weeks I didn't notice anything out the ordinary, but now in weeks 3/4 I have always got this banging headache which comes and goes, the occasional period of extreme sweats. And last of all a feeling in my head that I can't really describe, it feels like when I exert myself,stand or do any lite physical activity, that all the blood rushes from my head. I don't really know how else to describe it. But that's my experience thus far, hopefully it subsides. Anyone else had similar?
Prozac stays in your system for 25 days! I have been on a 40mg dose off and on for six years. I am going off it again now, but this time I'm doing it in a way that won't leave me in the hospital. Withdrawal symptoms include tiredness, irritability, CRAMPING, insomnia. Basically it's like being on your period 24/7, but the full side effects don't hit you until a month or 4 months later. It really depends on the amount and duration you've been taking Prozac. Remember unlike other anti-depressants Prozac will stay in your system for 25 days so you won't feel any withdrawal symptoms the day or two or week after you stop.
I am wheening off this powerful drug slowly and listening to my body. Once a day to a few times a week, once a week, twice a month, once a month, and finally.. Never again!
Okay has anyone found out if it is just the withdrawal that makes you feel like the Incredible Hulk, whole body he could feel like it was going to tingle its way out of your skin or is this the depression we felt before Prozac?
:) Hannah
A few more details
I have taken Prozac on and off for about 12 years but never stopped without getting on something else like lexapro. I can't even remember exactly what my depression looked like before Prozac so how do I know if this is withdrawal or who I actually am without it
-Hannah
I agree with you Hannah. I have been on them so long that I’m not sure what my normal was before them.
The rebound effect of depression/anxiety returning when stopping antidepressants is very common because the drug doesn't *cure* the illness ~ it controls the symptoms.
Unless someone is experiencing unbearable side effects I've never understood why they need to feel they must stop their medications.
Side effects of weight gain and low sex drive, which causes trouble in my relationship and makes me feel self conscious. This is my reason for coming off. Most of us are aware that we cannot be cured but just can’t live with the side effects. I am aware that some people with severe mental illness come off of it because they think they are cured but most of us struggle to deal with the side effect and are looking for help from others, like maybe suggestions of other medications.
I have been taking 20mg a day for 15 years. With my doctor's guidance, I recently tapered the dosage, and took the last tablet 3 weeks ago.
The first 2 weeks were great, but now I feel hollow, drained, dis-interested in life. Obviously, I cannot say whether this stage will pass, so cannot give a direct answer to your question, but at least I can say that I am there with you, and the hope that one day I will be free of both the drug and the withdrawal effects is enough for me to hold onto for now. If it shapes up to be a lifetime problem then it's back to the tablets for me.
I have been on 20 mg Prozac for 20 years. As I am aging, I would like to get off it. I ran out so started to get off it. In 4 days my refills came and I took one. I plan on one every 4 days for a week, then 2 a week for two weeks then quit. I am feeling super tired. I have talked to my doctor and he thinks this will be ok. If it isn't, can I go back on them?
Hi me too,
I had been taking prozac for a number of years and weaned myself off in February. It have been irritable my body aches, my feet hurt to walk on when I first start walking. I get some horrible feelings at times. I cry and feel sad. It is going on 5 months and I fear it will stay lime this. I read someone's post that said it was a year and a half and they still felt these symptoms. I hope that won't be my case because I am going to continue drug free!
If anyone out there can say they made it through the side effects of long term use to be medication free please post. I feel that my life has been taken from me. I thank others for posting the side effects of prozac use, and trying to be free of it. Good luck to all. Again, please post if you made it through the withdrawals and how long (months or years) it took for you.
High Five! So proud of you!!!
Wanted to research weaning off of Prozac due to my sudden bouts of crying and feeling anxious and irritable. This is not like me to be this way. I just start crying for no apparent reason. I had been on a fairly low dose of Prozac and a month ago my doctor thought I was doing well and could probably taper off. So, he cut the dosage down to half - now just 10 mg. I have to force myself to do things around the house - again, not like the normal me. I had been on Effexor for years and they should have named in "Side-effectsor". Getting off it was absolutely horrible with what I call "Brain zaps". So, from what I am reading my decrease in mg is probably causing the problems I am having. Now I'm wondering if I should just get back to 20 mg. The only problem with that is I would feel that I am going backwards and not sticking to getting off the meds. Having a hard time distinguishing if my feelings are due to the decrease in Fluoxitine or depression returning. Any suggestions would be welcome. Thank you!
I was on Prozac this last year along with an anti-anxiety med and before that Effexor for many years ... I weened off Effexor years ago and weened off off Prozac about 3 months now. the process was feeling great at the beginning. but now I want to sleep and the time and alienate my self from everything. Don't want to go to work... really being a recluse... Yet I've always been know to be social,etc.. I know being active, excercing is the answer,but I just don't care. my body aches and am sore everyday. I also have really crazy dreams that seem some weird dreams every night... I'm a mess...
I was on Prozac for 18 years , I increased to 40mgs 10 years ago. I started to realise six months ago that I was struggling to deal with issues 'normally' like I was wading through treacle, everything felt such hard work - a friend suggested that the Prozac was the problem and that it was slowing me down - I spoke to my gp and I weaned myself down to 20mg over a month - what a difference - I have clarity in my problem solving - I'm not tired as much or ' not bothered ' I did get some woozy feelings after 2 weeks but not much and it went within a month . I'm around 4 months in now - still taking 20mg and am planning to go to 10mg over the summer ( natural sun therapy I'm hoping ) I don't feel as frustrated with myself as if I can't do something I know it's not because I'm too doped up to try it . Prozac worked for me but once you feel weighed down by it I think the dose should be decreased - I'm so much better now
Hi
I have just found this post as I’m looking for help I’ve been off Prozac for 2 months and am experiencing the same symptoms as you have you got through it now if so could you help me understand what it’s like and how long it took you please
Have you recovered by now??
Hello i have taken prozac fluoxetine 10 mg capsules for about 4 to 5 years. I actually stopped taking them a couple months ago I would say 4. I have been feeling angry, moody, sadish lately and have been having really horrible headaches. I take ibuprofen, advil, and aleve alot so the headaches will stop. My sleeping schedule has been off. I'm tired and have really bad aches on my body(the back aches have been really bad and body aches). I'm wondering if this has to do with stopping the medication because it's been 4 months already or more so If so I thought it would stop but it seems only to be getting worse. I sometimes feel just bypolar in a way. And I am thinking of starting to take the medication again because of the mood swings but I had weight gain because of the medication. I feel it had effects on my body appearance. When i stopped taking meds my weight gain has caused me to have depression.
So I just don't want to take them if they are going to cause that. I will also see a doc I just wanted to know if anyone has similar problems :/
I forgot to add i have been having reallu really bad Anxiety and stress. I get very emotional. I just feel lwronsomething wrong with me in a way. Maybe causes of stopping the medications. I also moticed when i was taking the meds for a bit i hadnt been taking them regulary and i was having the same symptoms or withdrawals... The meds were not helping me as much as the first twi years.. I had felt angry and sad and just bypolar irritated while being in them the last year ... Maybe the dosage needed to be changed i really don't know.
I am just recently looking at your post. What you have wrote... Is exactly what has happened to me. I was on 40 mg for about 2 years. I wanted off. I quit and about 4 months later I experienced flu like symptoms. When they would not go away I decided to see a dr and they could find nothing wrong with me. For 1 1/2 years now I have fought body tingles, head aches, weight gain and EXTREME fatigue. I have just recently went back on a low dose of fluoxetine and the symptoms are going away. I actually went back on it just to see if that was what it was. Any information you have will be helpful.
Hello. I have experienced a lot of the same withdrawal symptoms you have. I was on fluoxetine for about 5 years taking 20mg a day. About 5 months ago I decided I didn't need it and was on it longer than I anticipated. I didn't really wean myself off like I should have but stopped taking it in January. I noticed extreme irritability. Everything and everyone was getting on my nerves. I was getting more mad easily and wanted to cry for no reason. I stuck it out hoping it would pass and it did but as of the end of February I started noticing horrible back and shoulder pain. I go to the gym regularly so I thought I may have hurt my back there but that wasn't the case. My neck started to get so stiff I could barely move it and my shoulders were constantly on fire. I seen 2 different orthopedic doctors, have multiple x rays, an MRI, did physical therapy, massages, acupuncture, and went to the chiropractor and still feel the same.
I am convinced now that this is long term effects of fluoxetine. My arms sometimes get tingly and numb when I lay a certain way and I have never had this before. I see my primary doc this coming week hoping he can give me some answers but at this point this is just ridiculous and I feel as if I'll always feel this way. The pain is so debilitating at times and in the morning is the worse trying to get out of bed. No one has figured out what is going on. I even had lots of blood work done making sure I don't have an auto immune disease and thank fully I don't but it's almost worse not knowing a direct answer. I've been debating going back on fluoxetine but I've already come this far without taking it. I'm not depressed because I'm not on it anymore, I'm depressed because I want this body aches and pains to go away. I've literally tried everything and nothing has helped. If I would have known this medication would have caused these withdrawal symptoms months later I would have never taken this drug.
Did it go away for you?
HI, I have been on prozac 60 mg for a very long time, several years, and I am planning to stay with it but I am interested in how the weaning goes. I also take wellbutrin XL to amplify the prozac and Lamictial as a stabilizer. Please let me know how you do, I may have to wean one day and all the info I can acquire is an asset. Good luck to you and stay in close contact with your health professionals. Tige
Related topics
prozac, depression, side effect, anxiety and stress
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- Prozac uses and safety info
- Prozac prescribing info & package insert (for Health Professionals)
- Side effects of Prozac (detailed)
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