I take 100mg of Seroquel twice a day, for schizophrenia.
Why can't I have grapefruit while taking seroquel?
Question posted by Bridie Jo Dennison on 24 Oct 2013
Last updated on 24 October 2013 by WildcatVet
Answers
WildcatVet
24 Oct 2013
Hi, Bridie! Just FYI, other fruit juices ~ orange, apple, grape, etc. ~ will not cause an interaction.
Best wishes, WCV
Cloch
24 Oct 2013
It has to do with the metabolism of Seroquel. Seroquel is metabolized in your liver by CYP3a4 enzymes. Grapefruit is a protent inhibitor of these enzymes. Taking the two together causes seroquel to accumulate and leads to potential side-effects.
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seroquel, schizophrenia, grapefruit
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