Hi, Skdennis! There are two potential interactions you should be aware of: low sodium levels (hyponatremia) and a rare condition called serotonin syndrome. Your doctor has likely determined that the benefits of these medications outweigh the risks but you should be alert for any unusual symptoms you might experience. These links will go into the details for you. If you have further concerns you should discuss them with your doctor. If more than one doctor has prescribed them be sure they both know all the medications you're taking.