Drinking heavy one night on Cymbalta?

I looked up Cymbalta on this website and it said to avoid alcohol because it could increase the risk for liver damage although a couple of drinks probably won't hurt as long as it isn't everyday. Its your choice. try talking to your doctor or a pharmacist. Hope I was of some help.

Hangover from hell is all I have to say. I mean, bed ridden for at least a day

The drug interaction checker warns of a moderate interaction between the two but that is based on Cymbalta possibly causing liver issues and adding alcohol which can potentially cause liver issues. Chucks advice sounds reasonable to me.

Very bad Combination but you don't want to do this often don't take the Cymbalta on the day you're going to be drinking and you will feel so bad the next day take it again the next day. normally if you did this with Cymbalta, my friend, you would feel like hell. otherwise, that is your choices no alcohol or hold the Cymbalta and don't get used to doing this you may still feel like crap on the day you restart the Cymbalta. one or the other my friend and have your friends look for extra sedation and cut you off a bit early or the alcohol hitting you harder. to cut you off. Enjoy and don't make a habit of this chuck1957

I am not trying to deter you, I was once your age and enjoyed those opportunities. Now I cannot afford the event or the alcohol so it easy for me to give advice. I wouldn't do but as they say "noir mileage may vary".