What is the downside of long term use (years) of omeprazole?

Long term use may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine.
Low magnesium levels have also been associated with long term use and levels should be tested periodically.
It is important to use the lowest doses and shortest duration of treatment necessary for the condition being treated.

Long term use for me was shortness of breath, pain in joints, gurgling in throat, nausea and coughing every morning, sinus infections, urinary tract infections and a "hiccuping" affect... rushed to hospital with breathing problem and CT Scan showed lungs were like shattered glass... I stopped the omeprazole and all of the above problems stopped! No more infections at all! But I am taking a zantac#150mg each day and the heartburn is so bad. So I take an omeprazole every so often and of course it helps tremendously but I immediately get the shortness of breath and my sinus' start on me... there are no anwers for a remedy except the outpatient procedure to have the muscle corrected and I am not ready to take myself there yet. But almost! This is all from long term use which I thought was only 8 years but I found it is more like 12 years I had been on omeprazole.
AquariusAnneCa