Does prednisone make you tired or sleepy?

Yes and no. I am on 40 mgs right now. I was on 60 2 weeks ago. On 60 i was awake 36 hrs straight 3× a week. Now, i am so exhausted and foggy brain. Hyper not eating, exhausted eating. One piece of advice: NEVER BUY SWEAT PANTS DUE TO CLOTHES GETTING TO TIGHT. I did that 30 yrs ago when I first had to do steroids and i gained 25 lbs in 2 month. 50lbs. in a year.. I should have just stopped eating when pants got tight but the hunger is very strong. In the last 2 months, I have only gained 4 lb no sweats, jeans only. Peace.

Yes. I have adrenal insufficiency too and taking prednisone makes me feel very weak. I have been to my doctor about this and they shrug their shoulders leaving me to try to figure this out in my own.They don't believe me, it's disheartening. Has anyone that has figured this out?

I was given a 5 day course of Prednisone to help with laryngitis due to a severe upper respiratory tract infection. First day, didn't notice anything different - granted I already felt crappy. Took the second one and crashed. I barely made it to my bed and then drifted in and out of sleep for several hours. There is no way I can take this and then go to work.

It can. Prednisone makes me exhausted and weak to the point where I can barely function.

I have been on prednisone for adrenal insufficiency since January of 2018. I am exhausted. The more I take, the worse it gets so I have to say, it gets old hearing that it is not the prednisone that is doing it. Sure it is. I do not even feel this tired without it. It's crazy how tired I am. All I keep hearing regarding the adrenal insufficiency is, you are not on enough. The higher the dose, the worse I feel, so I disagree. I am indoors sleeping due to prednisone.

I am exhausted on it and like someone else said, I can't make decisions or think. It's like an anesthesia type feeling. It's awful.

I don't know why people say, it can't be the prednisone. Sure it can!

Six days ago, I started a very low dose of prednisone (2.5mg), for undetermined autoimmune disease. There have been several times in the past, where I've taken a taper-pack, which I tolerated quite well. This low does is making me feel very peculiar-- spaced out and kinda tired, as if I'm my brain can't make decisions.

OMG!!! This stuff is kicking my butt!!! I almost just nose dived into my keyboard at work!!!
I feel like someone gave me a sedative. If I start drooling on myself, I am done...

Yes, I am on a round of prednisone now for severe asthma (exasperated) 40mg for a few days, 30 for a few, 20 on so on. I was nervous because my friend said it made his heart race. And the doctor told me to watch the carbs because of weight gain. Today is my first dose and I am tired and loopy, heart rates fine, no sweating etc... I guess everyone's body reacts different.

I took Prednisone for the first time about 45 mins ago and I'm having trouble keeping my eyes open. I'm thinking I should avoid taking it before driving in the morning but it's unfortunate to have to miss a dose.

I googled this subject because I have just taken prednisolone (for a skin rash) for the second time, and as last time it has wiped me out and I had to go to bed. Clearly not all bodies react in the same way - I'm relieved to find I'm not the only one!

For most people this is not the case. Prednisone works with the adrenaline system therefore for most people they are more edgy, have a hard time sitting still and difficulty sleeping. Some will gain weight and or have a swollen face often referred to as "moon face due to fluid retention. These symtoms are usually for people who gave been on it a while. A 5-7 day z pack will not cause these problems. Most will either have no trouble sleeping or will not be able to sleep or fall asleep easily. I have read that, for long term use, it has a stimulant effect, I have been on it for the better part of 30 yrs and sleep has always been hard to get.

Does predisone make me sleepy and or tired?

I am taking Prednisone for PMR, 3 mg per day. I noticed rather quickly that my sleep improved dramatically. I attributed this to the fact that, thanks to the Pred, I was no longer in pain with body movements. However lately I have been sleeping longer and longer at times--8 1/2 hours last night--and this afternoon while working on my computer I got sleepy and took a half hour nap. Not due to food as I'd had a very light lunch.

On prednisone i felt on a high and had insomnia, the sleepyness and extreme fatique happened after my course had finished, then reoccuring chest infections, muscle pain, lethargic... this drug is lethal... i have to go back on them at a high dose to clear up chest infections that dont respond to antibiotics... its a vicious cycle... now im on 5mg per day just to stop the joint aches from crippling me.

I'm currently on a course of Prednisone to treat sciatica, and I'm having a hard time staying away for more than 3-4 hours at a time. I'm on vacation this week so I'm napping several times a day, but wouldn't be able to take this during a normal work week, just cannot stay awake long enough to function normally.