Has anyone had night sweats & trouble staying asleep while taking Cymbalta & Wellbutrin or Pristiq?

You might want to watch out for this unusual side effect I had with Pristiq. I was getting great results with it to treat my depression, but I started getting bloody stools. I am sure it was from the Pristiq, as I tried starting it again a few months later, two more times, and the same exact thing happened. I wasn't taking any other medications.

Been on Pristiq for several years. On high dosage as well. I am doing great from the clinical standpoint and emotional standpoint. I do have night sweats and also have lots of nightmares, but in the long run, I am depression free!!! If you've been clinically depressed, then the side effects of the medication that works for you is a minimal sacrifice!

I have terrible nightsweats with the Cymbalta. I was switched to Pristiq and found it did nothing to me, did not help with the depression or anything. And of course i wake alot at night but I don't know if its my pain or the meds. Good luck and keep searching!

I could not take Cymbalta either. I felt like my mind was flying at night. It was awful! Then I started swelling up really bad in my hands, feet and face so I stopped it.

HI first of all what are you doin on both? And Wellbutrin can keep you up at night you have to take that early. I recommend to be taken off Wellbutrin, I had too many side effects do to the drug. I am on Cymbalta and have NO side effects. I take it in the morning. It can cause drowsiness but unaware of that effect on me. I think the nights sweats are from Wellbutrin NOT the Cymbalta. I have experienced it. Ask the doctor to be taken off of that as I am not a doctor but have been on many drugs and know side effects, trust me. To me Cymbalta is a life saver... I have no side effects to my knowledge, but do take in morning ok. I hope I helped you.

When I was on Wellbutrin, it had a distinct stimulating effect on me that was just part of the drugs effects for me. Pristiq also had a stimulating effect on me as well only for the first couple of days, then it went away. I no longer take either one of these, and take Effexor due to cost and no mental health insurance, and that one makes me sleepy! Never had the sweats. Just my experiences with these meds, and hope that it is helpful!
Jeff K

Hey ashes,

I recently switched to Pristiq from Cymbalta. I have had no problems with night sweats but I did have some problems at first with getting to sleep and some nausea. I have been on the Pristiq now for 6 weeks and am side effect free.

When I took Cymbalta I had a problem with excessive sweating. I have not had a problem with staying a sleep though. In fact, I liked to sleep too much and that is one reason I switched to the Pristiq. Each of us is different and therefore react differently to the meds.

Read about Pristiq by plugging it into the search window above and get a feel for it. It is similar to Effexor but has less side effects is the way my doctor described it. I have to point out that increased sweating is a common side effect of all of these antidepressants.

Keep me posted as to how you do if you decied to make the switch,

Laurie