What is the difference between prednisone and methylPrednisolone?

Prednisone is used for treating auto immune responses such as Inflammation of tissue in the body. Muscles or muscular related structures.

Methylprednisolone affects inflammation in skin tissue such as hives, dermatitis and related conditions. As the GI system is also skin derived it may help there as well.

Often the latter is given before infusions as it reduces the chances of an allergic response by shutting down the response to foreign cells.