I got a cortisone shot in my knee yesterday. I had no pain from the shot or around my knee for 2 hours. Then my leg from the just above the ankle to my thigh started to ache in extreme pain , I could hardly walk, I could not straighten my leg at the knee, and near the sight of the injection became feverous. I took two advil and put ice packs on my leg, but the symtoms did not start subsiding for almost 16 hours. Now it is just hard to bend my knee. Is this a common side effect. I had never had a cortisone shot before